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Contents Volume 12 Issue 8 August 26, 2020

Therapeutic and Diagnostic Guidelines

Hunting down the dominating subclone of cancer stem cells as a potential new therapeutic target in multiple myeloma: An artificial intelligence perspective

Lisa X Lee, Shengwen Calvin Li

World J Stem Cells 12(8):706-720. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.706

Abstract (968) | Core Tip (979) | Full Article (HTML) (4538) | Figures (1-6) (638) | Tables (1-2) (535) | Full Article (PDF)-7784K (563) | Audio-984K (16) | Peer-Review Report-259K (189) | Answering Reviewers-157K (184) | Received: 05/18/2020 | Revised: 07/08/2020 | Accepted: 08/13/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (23) | Total Visits (13505) | Similar Articles (81) | Timeline of Article Publication (3) | Authors Evaluation (2) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Opinion Review

Off-the-shelf mesenchymal stem cells from human umbilical cord tissue can significantly improve symptoms in COVID-19 patients: An analysis of evidential relations

Phuc Van Pham, Ngoc Bich Vu

World J Stem Cells 12(8):721-730. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.721

Abstract (962) | Core Tip (1561) | Full Article (HTML) (4149) | Figures (1-2) (1023) | Full Article (PDF)-1966K (524) | Audio-694K (10) | Peer-Review Report-856K (219) | Answering Reviewers-122K (186) | Received: 05/06/2020 | Revised: 05/21/2020 | Accepted: 08/01/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (13187) | Similar Articles (844) | Timeline of Article Publication (3) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Review

Mesenchymal stromal cells as potential immunomodulatory players in severe acute respiratory distress syndrome induced by SARS-CoV-2 infection

Panagiotis Mallis, Efstathios Michalopoulos, Theofanis Chatzistamatiou, Catherine Stavropoulos-Giokas

World J Stem Cells 12(8):731-751. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.731

Abstract (998) | Core Tip (962) | Full Article (HTML) (5385) | Figures (1-2) (702) | Tables (1-3) (487) | Full Article (PDF)-2698K (690) | Audio-820K (6) | Peer-Review Report-281K (170) | Answering Reviewers-307K (199) | Supplementary Material-85K (213) | Received: 05/15/2020 | Revised: 06/10/2020 | Accepted: 07/19/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (21) | Total Visits (14989) | Similar Articles (91) | Timeline of Article Publication (7) | Authors Evaluation (1) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Practical choice for robust and efficient differentiation of human pluripotent stem cells

Mei Fang, Li-Ping Liu, Hang Zhou, Yu-Mei Li, Yun-Wen Zheng

World J Stem Cells 12(8):752-760. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.752

Abstract (1020) | Core Tip (917) | Full Article (HTML) (3785) | Tables (1-1) (508) | Full Article (PDF)-778K (477) | Audio-615K (2) | Peer-Review Report-155K (193) | Answering Reviewers-50K (187) | Received: 03/28/2020 | Revised: 04/30/2020 | Accepted: 07/01/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (10862) | Similar Articles (42) | Timeline of Article Publication (3) | Authors Evaluation (3) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Human embryonic stem cells as an in vitro model for studying developmental origins of type 2 diabetes

Andy Chun-Hang Chen, Kai Fai Lee, William Shu Biu Yeung, Yin Lau Lee

World J Stem Cells 12(8):761-775. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.761

Abstract (1063) | Core Tip (1029) | Full Article (HTML) (4125) | Figures (1-1) (603) | Tables (1-1) (531) | Full Article (PDF)-1144K (495) | Audio-639K (12) | Peer-Review Report-197K (180) | Answering Reviewers-166K (173) | Received: 03/12/2020 | Revised: 04/28/2020 | Accepted: 06/14/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (8) | Total Visits (12285) | Similar Articles (122) | Timeline of Article Publication (2) | Authors Evaluation (4) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Autophagy in fate determination of mesenchymal stem cells and bone remodeling

Xiao-Dan Chen, Jia-Li Tan, Yi Feng, Li-Jia Huang, Mei Zhang, Bin Cheng

World J Stem Cells 12(8):776-786. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.776

Abstract (920) | Core Tip (896) | Full Article (HTML) (4941) | Figures (1-2) (1003) | Full Article (PDF)-2329K (462) | Audio-372K (0) | Peer-Review Report-199K (152) | Answering Reviewers-301K (208) | Received: 02/28/2020 | Revised: 05/17/2020 | Accepted: 06/20/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (16) | Total Visits (14295) | Similar Articles (243) | Timeline of Article Publication (3) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Stem cell therapy for Alzheimer's disease

Xin-Yu Liu, Lin-Po Yang, Lan Zhao

World J Stem Cells 12(8):787-802. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.787

Abstract (1340) | Core Tip (1140) | Full Article (HTML) (17768) | Tables (1-1) (656) | Full Article (PDF)-848K (1250) | Audio-2632K (130) | Peer-Review Report-233K (226) | Answering Reviewers-147K (239) | Received: 02/28/2020 | Revised: 04/10/2020 | Accepted: 07/26/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (117) | Total Visits (27192) | Similar Articles (77) | Timeline of Article Publication (11) | Authors Evaluation (7) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Exosomes derived from stem cells as an emerging therapeutic strategy for intervertebral disc degeneration

Zhi-Lei Hu, Hai-Yin Li, Xian Chang, Yue-Yang Li, Chen-Hao Liu, Xiao-Xin Gao, Yu Zhai, Yu-Xuan Chen, Chang-Qing Li

World J Stem Cells 12(8):803-813. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.803

Abstract (1138) | Core Tip (900) | Full Article (HTML) (5086) | Figures (1-1) (577) | Tables (1-2) (1025) | Full Article (PDF)-1435K (492) | Audio-1354K (14) | Peer-Review Report-288K (201) | Answering Reviewers-868K (344) | Received: 02/27/2020 | Revised: 06/09/2020 | Accepted: 07/05/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (38) | Total Visits (16209) | Similar Articles (144) | Timeline of Article Publication (0) | Authors Evaluation (3) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Mesenchymal stem cell-derived exosomes: Toward cell-free therapeutic strategies in regenerative medicine

Zhan-Jun Ma, Jing-Jing Yang, Yu-Bao Lu, Zhao-Yang Liu, Xue-Xi Wang

World J Stem Cells 12(8):814-840. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.814

Abstract (1085) | Core Tip (1107) | Full Article (HTML) (11404) | Figures (1-4) (1870) | Tables (1-3) (594) | Full Article (PDF)-7358K (881) | Audio-612K (17) | Peer-Review Report-191K (238) | Answering Reviewers-109K (214) | Received: 03/15/2020 | Revised: 04/23/2020 | Accepted: 06/27/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (83) | Total Visits (22371) | Similar Articles (63) | Timeline of Article Publication (5) | Authors Evaluation (7) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Basic Study

Assessment of tobacco heating system 2.4 on osteogenic differentiation of mesenchymal stem cells and primary human osteoblasts compared to conventional cigarettes

Romina H Aspera-Werz, Sabrina Ehnert, Monja Müller, Sheng Zhu, Tao Chen, Weidong Weng, Johann Jacoby, Andreas K Nussler

World J Stem Cells 12(8):841-856. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.841

Abstract (1150) | Core Tip (941) | Article Highlights (1742) | Full Article (HTML) (5459) | Figures (1-6) (527) | Full Article (PDF)-3471K (677) | Audio-2826K (15) | Peer-Review Report-242K (219) | Answering Reviewers-918K (378) | Received: 02/25/2020 | Revised: 07/17/2020 | Accepted: 08/01/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (18) | Total Visits (17438) | Similar Articles (138) | Timeline of Article Publication (4) | Authors Evaluation (7) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Human embryonic stem cell-derived mesenchymal stem cells improved premature ovarian failure

Khadijeh Bahrehbar, Mojtaba Rezazadeh Valojerdi, Fereshteh Esfandiari, Rouhollah Fathi, Seyedeh-Nafiseh Hassani, Hossein Baharvand

World J Stem Cells 12(8):857-878. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.857

Abstract (1207) | Core Tip (1034) | Article Highlights (1017) | Full Article (HTML) (7704) | Figures (1-5) (568) | Full Article (PDF)-13177K (764) | Audio-327K (6) | Peer-Review Report-197K (221) | Answering Reviewers-120K (227) | Supplementary Material-1400K (214) | Received: 02/22/2020 | Revised: 06/01/2020 | Accepted: 07/19/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (68) | Total Visits (18164) | Similar Articles (15) | Timeline of Article Publication (4) | Authors Evaluation (3) | Article Quality Tracking (0) | What about the content of this article? (0) | Cite |

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Systematic Reviews

Role of mesenchymal stem cell derived extracellular vesicles in autoimmunity: A systematic review

Jing-Hua Wang, Xiao-Ling Liu, Jian-Mei Sun, Jing-Han Yang, Dong-Hua Xu, Shu-Shan Yan

World J Stem Cells 12(8):879-896. Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.879

Abstract (978) | Core Tip (975) | Article Highlights (1044) | Full Article (HTML) (5732) | Figures (1-3) (702) | Tables (1-2) (532) | Full Article (PDF)-12603K (569) | Audio-1069K (20) | Peer-Review Report-242K (198) | Answering Reviewers-85K (224) | Received: 03/04/2020 | Revised: 07/02/2020 | Accepted: 07/19/2020 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (36) | Total Visits (16040) | Similar Articles (36) | Timeline of Article Publication (2) | Authors Evaluation (3) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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