Baishideng Publishing Group

Zhang ZH, Yue SY, Su M, Zhang HL, Wu QC, Li ZL, Zhang NJ, Hao ZY, Li M, Huang HJ, Ma J, Liu YY, Wang H. Overweight in mediating the association between depression and new-onset diabetes: A population-based research from Health and Retirement Study. World J Diabetes 2025; 16(3): 100245

"A short processing time is preferable. The format and edition of the manuscript is great. The online system can modify the reference ..." [Read more]

"A short processing time is preferable. The format and edition of the manuscript is great. The online system can modify the reference style. Peer review time is appropriate and a great help for improving the manuscript, and reviewers provide good feedback. The submission system is good. Overall, the publication process is fine. It is optional for authors to submit their manuscripts. " [Collapse]

Zhang CY, Liu S, Sui YX, Yang M. Nucleotide-binding domain, leucine-rich repeat, and pyrin domain-containing protein 3 inflammasome: From action mechanism to therapeutic target in clinical trials. World J Gastrointest Oncol 2025; 17(2): 100094

"No specific comments.It is our pleasure to receive this invitation to submit the manuscript titled “Preoperative gastric retention ..." [Read more]

"No specific comments.It is our pleasure to receive this invitation to submit the manuscript titled “Preoperative gastric retention in endoscopic retrograde cholangiopancreatography patients: assessing risks and optimizing outcomes” to the Editorial section of World Journal of Gastrointestinal Surgery. Endoscopic retrograde cholangiopancreatography (ERCP) remains a pivotal diagnostic and therapeutic tool in the management of pancreatic and biliary diseases. ERCP-related adverse events primarily include post-ERCP pancreatitis, cholangitis, bleeding, and perforation. Preoperative gastric retention and its associated adverse events have not been adequately recognized. Jia and colleagues conducted a retrospective analysis on patients who underwent ERCP preparation, analyzed factors influencing preoperative gastric retention in ERCP and established a predictive model to predict the occurrence of preoperative gastric retention in ERCP. We shared our opinion about this predictive model. First, further prediction of different degrees of gastric retention may be more beneficial. Second, we ponder whether this predictive model can be generalized to predictions of gastric retention before different endoscopic procedures. Third, large retrospective datasets and prospective clinical validation are needed to improve the prediction model. " [Collapse]

Zhou NY, Hu B. Preoperative gastric retention in endoscopic retrograde cholangiopancreatography patients: Assessing risks and optimizing outcomes. World J Gastrointest Surg 2024; 16(12): 3655-3657

"Thank the reviewers and editors for their professional advice. . Your careful evaluation and insightful comments have greatly enhanced ..." [Read more]

"Thank the reviewers and editors for their professional advice. . Your careful evaluation and insightful comments have greatly enhanced the quality and integrity of the manuscript. The language modification certification seems unnecessary. Because AI can improve language very well nowadays. We have to spend additional money to get the certification. Thus, We hope the editors will consider cancelling the language certification. " [Collapse]

Xia Y, Hu Y, Ma JH. Premixed insulin: Advantages, disadvantages, and future. World J Diabetes 2025; 16(3): 102526

"You're doing a great job. The magazine is rich and diverse, covers a wide range of fields, and the articles are of high quality, depth ..." [Read more]

"You're doing a great job. The magazine is rich and diverse, covers a wide range of fields, and the articles are of high quality, depth and breadth. The layout design is beautiful and generous, and the reading experience is excellent. Each issue has new ideas and makes people full of expectations. For readers, it is not only a source of information, but also an inspiration of ideas, which is highly recommended. " [Collapse]

Liao XH, Sun YM, Chen HB. New classification of gastric polyps: An in-depth analysis and critical evaluation. World J Gastroenterol 2025; 31(7): 101467

"Thank you very much for your recognition of our work, and help us publish our findings.Help us adjust the deficiencies in the ..." [Read more]

"Thank you very much for your recognition of our work, and help us publish our findings.Help us adjust the deficiencies in the article,and all the procession are very smooth and effecient.I am very happy to finish the publication of this article with you.We will continue to submiss our study in future, and We look forward to more cooperation in future. " [Collapse]

Chen XH, Xia W, Ma JB, Chen J, Hu J, Shi X, Yu JJ, Gong J, Liu L, Sun YA, Liu ZG. Rare mixed dementia: A case report. World J Radiol 2025; 17(1): 102579

"I am extremely grateful to the World Journal of Diabetes for their professional support and efficient services throughout the ..." [Read more]

"I am extremely grateful to the World Journal of Diabetes for their professional support and efficient services throughout the submission process. The submission system was user-friendly and straightforward, making the entire experience seamless. The peer review process was thorough and constructive, with detailed feedback from reviewers that provided valuable insights and improvements for our research. Additionally, the editorial team demonstrated excellent communication and offered patient guidance, ensuring a smooth and pleasant submission journey. This experience not only deepened my understanding of academic writing and research presentation but also inspired new ideas and growth in our scholarly pursuits. Thank you again to the World Journal of Diabetes for providing such a high-quality platform for researchers! " [Collapse]

Liu MJ, Pei JY, Zeng C, Xing Y, Zhang YF, Tang PQ, Deng SM, Hu XQ. Triglyceride-glucose related indices as predictors for major adverse cardiovascular events and overall mortality in type-2 diabetes mellitus patients. World J Diabetes 2025; 16(3): 101488

"What impresses me most is that the submission system is concise and detailed, which enables you to know exactly what stage your ..." [Read more]

"What impresses me most is that the submission system is concise and detailed, which enables you to know exactly what stage your manuscript is at. In addition, the Editors are very prompt in processing the manuscripts, although the process of inviting a sufficient number of reviewers can be a bit tough, due to the fact that a number of reviewers are not very receptive to reviewing the manuscripts. " [Collapse]

Yang YJ, Zhou XC, Tian HR, Liang FX. Electroacupuncture relieves type 2 diabetes by regulating gut microbiome. World J Diabetes 2025; 16(3): 103032

""I recently submitted a manuscript through the online submission system and I must say, the experience was exceptionally smooth and ..." [Read more]

""I recently submitted a manuscript through the online submission system and I must say, the experience was exceptionally smooth and efficient. The platform was user-friendly and well-organized, guiding me step-by-step through the submission process. I appreciated how clearly the requirements were outlined, with detailed instructions for formatting, uploading documents, and filling out necessary metadata. The system's automated checks ensured that my files were properly formatted before submission, saving me potential delays. Additionally, the communication from the editorial office was prompt and professional. I received confirmation emails at every critical stage, including submission, peer review, and decision-making, which kept me informed and reassured throughout the process. The interface also allowed for easy tracking of my manuscript's progress, with clear updates on where it stood in the review cycle. The responsiveness of the support team was another highlight—they quickly addressed any questions I had, making the overall process stress-free. In summary, the online submission system was a pleasure to use, reflecting the journal's commitment to efficiency and author satisfaction. I would highly recommend this journal to colleagues for future submissions." " [Collapse]

Latsios G, Sanidas E, Velliou M, Nikitas G, Bounas P, Parisis C, Synetos A, Toutouzas K, Tsioufis C. Cardiac arrest: Pre-hospital strategies to facilitate successful resuscitation and improve recovery rates. World J Cardiol 2025; 17(1): 100782

""I recently submitted a manuscript through the online submission system and I must say, the experience was exceptionally smooth and ..." [Read more]

Latsios G, Dimitroglou Y, Lazaros G, Alexopoulos N, Tolis I, Aggeli C, Tsioufis C. Differentiating between immune checkpoint inhibitor-induced myocarditis and cardiac metastasis in a cardio-oncology patient presenting with myocardial infarction: A case report. World J Radiol 2025; 17(1): 100794

"A satisfying submission experience. The entire process was not only smooth but also enriching. I had the chance to enhance my skills, ..." [Read more]

"A satisfying submission experience. The entire process was not only smooth but also enriching. I had the chance to enhance my skills, learn from valuable feedback, and refine my work. The opportunity to contribute to such a meaningful platform was incredibly rewarding. I felt both challenged and supported throughout the journey, and it motivated me to continue improving. Overall, it was an unforgettable experience that contributed significantly to my personal and professional growth." " [Collapse]

Le XY, Feng JB, Guo Y, Zhou YQ, Li CM. Predicting preoperative lymph node metastasis in esophageal cancer: Advancement and challenges. World J Clin Oncol 2025; 16(3): 102863

"Good experience. Professional and ethical approach. Prompt publication. The communication via email can be improved. Clarity in working ..." [Read more]

"Good experience. Professional and ethical approach. Prompt publication. The communication via email can be improved. Clarity in working style. Grateful to the BPG for providing this opportunity to me. Thankful for the article invitation. Innovative techniques utilized for publication. Transparent working process. All editors did a splendid job. Coordinated effort and in depth review by the reviewers. " [Collapse]

Sharma A, Jain R, Satija J, Sharma A, Sharma A, Shekhawat S. Cluster sampling methodology to evaluate immunization coverage. World J Methodol 2024; 14(3): 92344

"I am deeply satisfied with my experience of submitting and publishing with your esteemed journal. The editorial team demonstrated ..." [Read more]

"I am deeply satisfied with my experience of submitting and publishing with your esteemed journal. The editorial team demonstrated a high level of professionalism and rigor throughout the entire publication process. Their work was efficient, and communication was prompt, providing great support and convenience to authors. The peer review process was strict, well-structured, and constructive, with insightful and detailed comments that significantly enhanced the scientific quality and academic value of my manuscript. Although the journal is still in the process of further establishing its prominence in the academic community, I believe it excels in submission experience, editorial efficiency, and review quality, providing an efficient and reliable platform for researchers. I would recommend this journal to researchers in related fields and encourage scholars to consider submitting their work here. I sincerely thank the journal for providing me with this valuable opportunity to publish my work. I look forward to future collaborations with the journal to contribute more high-quality research. " [Collapse]

Ma HR, Zhang D, Li L, Qi L, Wang L, Li YT, Wang YR. Targeted maintenance therapy for a young woman with cervical rhabdomyosarcoma: A case report and review of literature. World J Clin Oncol 2025; 16(3): 101909

"Author's Comments of [World Journal of Clinical Oncology] I am truly delighted to have had the opportunity to publish my article in ..." [Read more]

"Author's Comments of [World Journal of Clinical Oncology] I am truly delighted to have had the opportunity to publish my article in World Journal of Clinical Oncology. This journal has established a remarkable reputation in the academic community, and I feel honored to be one of its published authors. The journal's influence is undeniable. It consistently features high-quality research across a wide range of topics, which not only keeps the readers updated with the latest trends in the field but also sets a high standard for academic works. It serves as a crucial platform for scholars to disseminate their findings and contribute to the advancement of knowledge. The editorial team deserves special mention. They are highly professional, efficient, and dedicated. From the moment I submitted my manuscript, I received prompt responses. The initial review process was thorough, and the feedback provided was constructive and valuable. The editors' suggestions significantly improved the quality of my article, helping me to present my research more clearly and effectively. Moreover, the publication process was smooth and well-organized. The team was always available to answer my questions and guide me through each step, which made the entire experience stress-free. I really appreciate their support and assistance. In conclusion, I have had an excellent experience working with World Journal of Clinical Oncology. I would highly recommend this journal to other researchers. I look forward to the possibility of contributing to it again in the future. Zuyuan Chen 2025-01-21 " [Collapse]

Pang YY, Chen ZY, Zeng DT, Li DM, Li Q, Huang WY, Li B, Luo JY, Chi BT, Huang Q, Feng ZB, He RQ. Checkpoint kinase 1 in colorectal cancer: Upregulation of expression and promotion of cell proliferation. World J Clin Oncol 2025; 16(3): 101725

"The World Journal of Clinical Oncology demonstrates a high level of academic credibility, publishing research that is clinically ..." [Read more]

"The World Journal of Clinical Oncology demonstrates a high level of academic credibility, publishing research that is clinically significant and impactful. The peer review process was rigorous and constructive, with detailed feedback that greatly improved the quality of our manuscript. The editorial team was highly professional and maintained excellent communication throughout the submission and publication process. Overall, we had a positive and efficient publication experience. We appreciate the journal's dedication to academic excellence and look forward to submitting future studies " [Collapse]

Lin ZP, Zou XG, Huang DB, Chen Y, Lin JW, Li XQ, Zhang J. Efficacy and safety of C-arm computed tomography-guided microwave ablation with percutaneous osteoplasty for flat bone metastases. World J Clin Oncol 2025; 16(3): 101681

"The editors and staff of the World Journal of Clinical Cases are highly professional and patient. They assist authors in a fair and ..." [Read more]

"The editors and staff of the World Journal of Clinical Cases are highly professional and patient. They assist authors in a fair and transparent manner to make corrections and meet publication requirements, while also respecting the authors' expertise and maintaining the integrity of the article. This is a journal worth reading and submitting to. " [Collapse]

Fan Y, Yu JH, Chen YH. Improved super-elastic Ti-Ni alloy wire for the angle class III patient with anterior open bite: A case report. World J Clin Cases 2025; 13(15): 101884

"The journal editor's revisions and proofreading of my paper have improved the image quality of my paper. The downside is that there ..." [Read more]

"The journal editor's revisions and proofreading of my paper have improved the image quality of my paper. The downside is that there is only one reviewer in peer review, and it would be nice if there were 2-3 reviewers. Although the reviewers have made positive comments about the quality of the paper, I hope that the reviewers will come up with constructive revisions to further improve the quality of the paper. " [Collapse]

Zhao JH, Wang JJ, Li YW. Granulomatosis with polyangiitis induced by the anti-programmed cell death-1 inhibitor tislelizumab: A case report. World J Clin Cases 2025; 13(15): 103239

"Sodium-glucose cotransporter-2 (SGLT2) inhibitors are innovative antidiabetic agents that lower blood glucose by promoting its ..." [Read more]

"Sodium-glucose cotransporter-2 (SGLT2) inhibitors are innovative antidiabetic agents that lower blood glucose by promoting its excretion via the kidneys. Beyond their glucose-lowering effects, SGLT2 inhibitors have demonstrated significant cardiovascular benefits in clinical trials. Emerging basic science research indicates that SGLT2 inhibitors also positively impact pulmonary vascular health. They enhance the function of pulmonary vascular endothelial cells, inhibit the proliferation and migration of pulmonary smooth muscle cells, reverse pulmonary arterial remodeling, and help maintain hemodynamic stability. This review consolidates current findings on the mechanisms by which SGLT2 inhibitors improve pulmonary vascular cell function and arterial remodeling, suggesting new therapeutic possibilities for pulmonary vascular diseases. " [Collapse]

Zhang JJ, Ye XR, Liu XS, Zhang HL, Qiao Q. Impact of sodium-glucose cotransporter-2 inhibitors on pulmonary vascular cell function and arterial remodeling. World J Cardiol 2025; 17(1): 101491

"I was very satisfied with the peer review, editorial review, publication and other procedures in the publishing process, during which ..." [Read more]

"I was very satisfied with the peer review, editorial review, publication and other procedures in the publishing process, during which all questions were communicated to me by email as soon as possible and correct revisions were made in time. If there is an opportunity, I hope to continue to have in-depth cooperation with the World Journal of Cardiology in the future and publish our manuscript on it. " [Collapse]

Wang JN, Zhou YY, Yu YW, Chen J. Profiling and bioinformatics analyses of circular RNAs in myocardial ischemia/reperfusion injury model in mice. World J Cardiol 2025; 17(1): 102147

"Many thanks to the journal editors and reviewers. I have no further comments. The process is a bit lengthy, and many documents must ..." [Read more]

"Many thanks to the journal editors and reviewers. I have no further comments. The process is a bit lengthy, and many documents must be submitted. I hope to make it easier by eliminating unnecessary documents. Thanks again for the usual support, and looking forward to submitting more articles Best regards Abdulqadir " [Collapse]

Farsakoury R, Nashwan AJ. Revitalizing upper blepharoplasty: Preserving volume. World J Clin Cases 2025; 13(15): 100563

17943 items Read more >>

Article Quality Tracking-Peer-Review

"Overall, this article possesses both notable strengths and areas ripe for enhancement. The experimental methodologies are exhaustively ..." [Read more]

"Overall, this article possesses both notable strengths and areas ripe for enhancement. The experimental methodologies are exhaustively described, encompassing processes from tissue chip handling to cell-based assays such as CCK8, transfection, and western blot. These procedures are sufficiently detailed to allow fellow researchers to replicate the experiments. The results appear credible and authenticate the hypothesis that OCT4 influences pancreatic cancer cell behavior. The figures and tables are generally well-structured and clearly convey the data, albeit with some figure legends that could benefit from further elaboration. The biostatistical data seems appropriate, utilizing suitable statistical tests. However, a significant limitation lies in the absence of a thorough exploration of the clinical implications. Furthermore, the study's generalizability might be constrained due to the utilization of only one cell line (BxPC-3). Additionally, the lack of in-vivo validation represents a notable drawback." [Collapse]

"Upon evaluating the article, it becomes evident that the author has taken several commendable steps to ensure the ethical integrity ..." [Read more]

"Upon evaluating the article, it becomes evident that the author has taken several commendable steps to ensure the ethical integrity of the research, as evidenced by the provided ethical approval, although the inclusion of an approval number would further strengthen transparency. The experimental method described is effective and detailed enough to allow for replication by fellow researchers, which is crucial for the validation of scientific findings. The results presented are credible, partially validating the theory or hypothesis proposed. The figures and tables are well-constructed and annotated, facilitating easy comprehension of the data. Furthermore, the biostatistical analysis adheres to standard practices, ensuring the accuracy of the conclusions drawn. However, despite these strengths, the study has some drawbacks. Notably, the research is somewhat basic, lacking an in-depth exploration of the underlying mechanisms. To enhance the contribution of the study, the author could consider incorporating additional experiments or analyses to delve deeper into these mechanisms. Overall, while the article demonstrates a solid foundation in terms of methodology and results, further development is needed to address the existing gaps and elevate the research to a higher level of significance." [Collapse]

Li J, Wang ZY, Jin Y, Xu J, Ya YJ, Wan TQ, Li X, Wang X. Transmembrane channel-like 5 drives hepatocellular carcinoma progression by regulating epithelial-mesenchymal transition. World J Clin Oncol 2025; 16(3): 94091

"This editorial provides a timely and insightful discussion on how ChatGPT and other AI tools could transform diabetes management. ..." [Read more]

"This editorial provides a timely and insightful discussion on how ChatGPT and other AI tools could transform diabetes management. It effectively highlights their potential in patient education, dietary guidance, and clinical decision support while also acknowledging critical ethical and accuracy concerns. The discussion on diabetic retinopathy screening, obesity assessment, and AI-generated treatment recommendations is particularly relevant, showing the growing role of AI in healthcare. However, some key gaps remain. First, there is no clear evaluation of how well ChatGPT actually performs in diabetes care compared to existing tools or human experts. More studies testing its accuracy and reliability in real-world scenarios are needed. Second, while the paper mentions challenges like data privacy and AI errors, it does not propose specific solutions. Future research should explore ways to fine-tune AI models using diabetes-specific data and ensure medical supervision of AI recommendations. Finally, a broader comparison of ChatGPT with other AI models like Google Bard and Microsoft Bing would add depth to the discussion. Going forward, research should focus on validating AI tools in clinical practice, ensuring they improve patient outcomes rather than just providing information. More AI models specialized in diabetes could also help make these tools safer and more reliable. Overall, while this editorial is a valuable contribution, it would benefit from a more structured analysis of AI’s real-world effectiveness and ethical safeguards." [Collapse]

Sridhar GR, Gumpeny L. Prospects and perils of ChatGPT in diabetes. World J Diabetes 2025; 16(3): 98408

"Authors studied the role of serum retinol-binding protein (RBP) as a potential biomarker for lower limb atherosclerosis in individuals ..." [Read more]

"Authors studied the role of serum retinol-binding protein (RBP) as a potential biomarker for lower limb atherosclerosis in individuals with type 2 diabetes mellitus (T2DM). RBP, a primary transport protein for vitamin A, has been implicated in metabolic and inflammatory processes, yet its association with diabetes-related vascular complications, particularly lower limb atherosclerosis, remains unclear. Authors reported a linear correlation between RBP levels and lower limb atherosclerosis risk. The inclusion of 4,428 patients enhances the statistical power and generalizability of the findings. Identification of serum RBP as a biomarker for lower limb atherosclerosis may guide risk stratification and early intervention in T2DM patients. However, several limitations were notable: - The absence of follow-up data precludes the assessment of changes in RBP levels over time and their impact on disease progression. - The study’s retrospective nature limits its ability to establish causal relationships between serum RBP levels and atherosclerosis. - The study does not explore interactions between RBP and other biomarkers or pathways involved in atherosclerosis. - Authors did not evaluate interventions to modulate RBP levels or their impact on atherosclerosis risk reduction. " [Collapse]

Zhang YL, Peng GL, Leng WL, Lian Y, Cheng LQ, Li X, Wang YL, Zhou L, Long M. Association between serum retinol-binding protein and lower limb atherosclerosis risk in type 2 diabetes mellitus. World J Diabetes 2025; 16(3): 98590

"This study identifies key risk factors for diabetic foot (DF) in hospitalized patients with type 2 diabetes and develops a predictive ..." [Read more]

"This study identifies key risk factors for diabetic foot (DF) in hospitalized patients with type 2 diabetes and develops a predictive model with strong discrimination (AUC = 0.797). Notably, it reveals a U-shaped relationship between fasting plasma glucose (FPG) and DF and highlights serum albumin as a protective factor. However, the model lacks external validation and is limited to a single-center dataset, raising concerns about generalizability. Missing data on HbA1c and medication use may affect the comprehensiveness of the findings, and further prospective, multicenter studies are needed to confirm causality. Despite these limitations, the study provides valuable insights that could guide early risk assessment and prevention strategies for DF in clinical practice." [Collapse]

Li MZ, Tang F, Liu YF, Lao JH, Yang Y, Cao J, Song R, Wu P, Wang YB. Risk factors and a predictive model of diabetic foot in hospitalized patients with type 2 diabetes. World J Diabetes 2025; 16(3): 95644

"Authors studied the role of LEF1 and related RNAs in the pathogenesis of diabetic retinopathy (DR), focusing on their regulatory ..." [Read more]

"Authors studied the role of LEF1 and related RNAs in the pathogenesis of diabetic retinopathy (DR), focusing on their regulatory effects on endoplasmic reticulum (ER) stress, inflammation, and ferroptosis in retinal cells. By elucidating the molecular mechanisms underlying DR progression, the study aims to identify potential therapeutic targets. Authors found that streptozotocin-induced diabetic rats showed improvement in retinal health with LEF1 knockdown, as observed in reduced retinal damage (via HE staining) and inflammation. The study relies solely on cellular and animal models, which may not fully replicate human DR pathology. Moreover, impact of LEF1 knockdown on long-term DR progression and retinal function remains unaddressed. In addition, authors identified potential targets, but they did not comment on the feasibility, safety, or efficacy of translating LEF1 knockdown or related interventions into clinical treatments. Authors focused on GRP78 but did not explore other key players in ER stress pathways, which may also influence DR progression." [Collapse]

Luo YY, Ba XY, Wang L, Zhang YP, Xu H, Chen PQ, Zhang LB, Han J, Luo H. LEF1 influences diabetic retinopathy and retinal pigment epithelial cell ferroptosis via the miR-495-3p/GRP78 axis through lnc-MGC. World J Diabetes 2025; 16(3): 92003

"1. The narration of sequence of events after trauma is not easily understandable. Details regarding presentation and imaging findings ..." [Read more]

"1. The narration of sequence of events after trauma is not easily understandable. Details regarding presentation and imaging findings can help in better understanding. 2. Was the cause for peritonitis identified during the first surgery? 3. The dense adhesions probably dveeloped after the bowel involvement followed by sepsis which resulted in adhesions which were dense 4. The stoma non functioning was probably due to adhesive bowel obstruction secondary to bands, fibrosis and sequelae. 5. Preventive aspect may include early diagnosis, elimination of sepsis and aggressive lavage to prevent adhesion formation" [Collapse]

Xu R, Sun LX, Chen Y, Ding C, Zhang M, Chen TF, Kong LY. Stoma occlusion caused by abdominal cocoon after abdominal abscess surgery: A case report. World J Clin Cases 2025; 13(15): 98608

"1. Were other differentials for postop hypoventilation considered? List includes incomplete reversal of neuromuscular blocking agents, ..." [Read more]

"1. Were other differentials for postop hypoventilation considered? List includes incomplete reversal of neuromuscular blocking agents, opioid use, Acetyl choline esterase deficiency, background respiratory insufficiency, etc 2. Uncommon factors can include multifactorial causes such as viral, drug induced, neuromuscular disorders. 3. Metabolic disorders, storage disorders, late presenting neuropathy / myopathy, acquired progressive musculoskeletal disorders are other disorders to consider in the evaluation. 4. Inclusion of an algorithm / table would enhance the understanding " [Collapse]

Park SY, Hong SM, Lee HY, Kim MY, Lee HK, Han JY, Cho HJ, Oh SI, Lee H. Mitochondrial myopathy revealed postoperative acute respiratory failure: A case report. World J Clin Cases 2025; 13(15): 102691

"There are many causes of acute pancreatitis, but the three major causes are alcohol-related, biliary tract disease, and idiopathic ..." [Read more]

"There are many causes of acute pancreatitis, but the three major causes are alcohol-related, biliary tract disease, and idiopathic pancreatitis of unknown etiology. In Japan, these account for 20.4%, 26.6%, and 40.0% of cases, respectively.5) Other causes are rare, and the proportion of cases caused by hyperparathyroidism is also extremely low. The mechanism by which primary hyperparathyroidism causes acute pancreatitis is as follows: 1. Hypercalcemia causes pancreatic stones to form in the pancreatic duct, causing blockage, and the pancreas becomes inflamed. 1. The theory that high calcium ions promote the activation of intrapancreatic trypsinogen to trypsin, which causes pancreatitis. 2. The theory that high calcium ions promote the activation of intrapancreatic trypsinogen to trypsin, which causes pancreatitis. 3. The theory that excessive secretion of parathyroid hormone directly causes pancreatitis. However, none of these theories can explain everything, Especially during pregnancy., How old were the patients in question? Which of the above mechanisms is most likely to cause pancreatitis? " [Collapse]

Luong TV, Le LD, Nguyen NVD, Dang HNN. Persistent challenges in the diagnosis of acute pancreatitis due to primary hyperparathyroidism during pregnancy. World J Gastroenterol 2025; 31(7): 100973

"Thank you for the opportunity of appraising the quality of the following manuscript: 1 Ethics: Not applicable given manuscript ..." [Read more]

"Thank you for the opportunity of appraising the quality of the following manuscript: 1 Ethics: Not applicable given manuscript type 2 Methods: Not applicable given manuscript type 3 Results: Not applicable given manuscript type 4 Figures and tables: The tables/figures add to the readability of the manuscript 5 Biostatistics: Not applicable given manuscript type 6 References: The included references are appropriate and up to date 7 Language: This is a concise/well-written review 8 Caveats or drawbacks: None " [Collapse]

Liao XH, Sun YM, Chen HB. New classification of gastric polyps: An in-depth analysis and critical evaluation. World J Gastroenterol 2025; 31(7): 101467

"Important study, but a little bit general and not very distinctive. I would have tried to find time ranges and limits within which ..." [Read more]

"Important study, but a little bit general and not very distinctive. I would have tried to find time ranges and limits within which treatments of specific kinds in particular populations with regard to the etiology of the obstruction would have given best results, and types and rates of morbidities that would be expected at any time point. This gives a good guide to the clinician to choose the best approach in different conditions." [Collapse]

Gembillo G, Spadaro G, Santoro D. Link between obstructive uropathy and acute kidney injury. World J Nephrol 2025; 14(1): 99120

"Pancreatic primitive neuroectodermal tumors: Clinical features, treatment, and influencing factors World J Gastrointest Oncol ..." [Read more]

"Pancreatic primitive neuroectodermal tumors: Clinical features, treatment, and influencing factors World J Gastrointest Oncol 2025; 17(2): 97298 [DOI: 10.4251/wjgo.v17.i2.97298] The topic of this manuscript is crucial to the readers of this journal and those interested in pancreatic tumours. However, I have a few comments to the authors The paper is not clearly written, The abstract aim is not consistent with the methods. You need to explain why you searched the literature if you have mentioned the aim to analyse 30 patients. Later, I realised that this was a mini literature review. The authors must very early state that this is a mini-review of the literature, and when you refer to 30 patients, you must state that 30 patients were reported in the literature as case reports. The title should also indicate that it is a mini-review. It cannot fulfil the criteria of a Systematic Review. You should, in the introduction, show a comparison between pancreatic neuroendocrine tumours and primary neuroectodermal tumours of the pancreas. The inclusion of the Ewings tumours in the table is not well justified and can be debated. These two cases should have been excluded. Also, I have concern about the number given for PRESPERO registration it is not functioning and typing the tumour type also does not show your protocol or any related matters. The aims and the methods section should state that this is a mini-review, The country of each case should be stated in the table. The language of the manuscript needs editing. " [Collapse]

He YF, Wang HZ, Hu XD, Liu JQ, Li HM, Wang J, Lu SF. Pancreatic primitive neuroectodermal tumors: Clinical features, treatment, and influencing factors. World J Gastrointest Oncol 2025; 17(2): 97298

"Prognostic value of inflammatory markers in predicting recurrence-free survival in gastrointestinal stromal tumor patients: A ..." [Read more]

"Prognostic value of inflammatory markers in predicting recurrence-free survival in gastrointestinal stromal tumor patients: A nomogram-based approach World J Gastrointest Oncol 2025; 17(2): 94956 [DOI: 10.4251/wjgo.v17.i2.94956] I congratulate the authors on publishing the above-titled manuscript. The authors are targeting an important research question in gastrointestinal oncology, and they used several biomarkers to provide an answer to their research question. I have three comments- 1. Introduction- The justification from the literature for selecting the inflammatory-driven tumourigenesis / biomarkers should have been explained in-depth, showing the scientific grounds for selecting each and their accuracy, sensitivity, specificity, PPV, and NPP as per published studies. The statement, " and in other malignant diseases," needs a reference. 2. More details in the method section under Blood Sample and analysis should be provided. Only Ref 11 was given. Methods of measurement should be stated. 3.It would be ideal to compare this method with another method published in the literature. However, maybe in a retrospective study, such a comparison is difficult. If the authors plan for another non-retrospective, they may compare this method with a method published in the literature and compare the parameters for each. " [Collapse]

Zhao JL, Wang MY, Lv YZ, Zhou YJ. Prognostic value of inflammatory markers in predicting recurrence-free survival in gastrointestinal stromal tumor patients: A nomogram-based approach. World J Gastrointest Oncol 2025; 17(2): 94956

"1. Why was the child formula fed? Was it formula / cow milk? 2. Did the child have any abnormal facies on examination? 3. Esoinophils ..." [Read more]

"1. Why was the child formula fed? Was it formula / cow milk? 2. Did the child have any abnormal facies on examination? 3. Esoinophils can be expressed as part of the differential count or absolute eosinophil count for better understanding 4. The history taking to include the type / volume / nature of feeds as a routine 5. Learning point also can include feeding which can aid in the diagnosis, especially in atypical clinical features not co relating with the overall suspicion and diagnosis" [Collapse]

Jiang HH, Tang Q, Huang L, Yun X, Shan QW, Chen XQ. Severe upper gastrointestinal hemorrhage due to milk protein allergy: A case report. World J Clin Cases 2025; 13(14): 104039

"1. In the history, "tender lymphadenopathy with draining lymph nodes" points to atypical features not fitting with the picture of ..." [Read more]

"1. In the history, "tender lymphadenopathy with draining lymph nodes" points to atypical features not fitting with the picture of Inflammatory Bowel Disease 2. Atypical history combined with non classical scopy findings probably to raise suspicion and point to a different diagnosis 3. The occupation is not mentioned. It may be relevant, given the final diagnosis. 4. Marital status is probably another indirect clue. 5. The history to consider inclution of the above relevant details to avoid misdiagnosis " [Collapse]

Khoury KM, Jradi A, Karam K, Fiani E. Lymphogranuloma venereum proctosigmoiditis misdiagnosed as inflammatory bowel disease: A case report. World J Clin Cases 2025; 13(14): 102791

"1. The title can include recipient extubation for clarity 2. The operating time appears to be different for both the groups. Did ..." [Read more]

"1. The title can include recipient extubation for clarity 2. The operating time appears to be different for both the groups. Did prolonged surgical time have a bearing on extubation? 3. Diffcult anatomy / reconstruction - was it given consideration during the analysis? 4. Was the surgeon factor considered across the groups - senior / junior? 5. What about the anesthesia team - was it the same across the groups? 6. Limiting factors - non randomisation / surgeon / anesthetist factors" [Collapse]

Jeon S, Lim DG, Kim H, You SB, Kim HJ, Yoon JP, Yang K, Park SJ, Ri HS. Relevant clinical factors for early extubation in living-donor liver transplantation: A single-center retrospective cohort study. World J Clin Cases 2025; 13(14): 102693

"Unveiling expression patterns, mechanisms, and therapeutic opportunities of transmembrane protein 106C: From pan-cancers to ..." [Read more]

"Unveiling expression patterns, mechanisms, and therapeutic opportunities of transmembrane protein 106C: From pan-cancers to hepatocellular carcinoma World J Gastrointest Oncol 2025; 17(2): 92437 [DOI:10.4251/wjgo.v17.i2.92437] I congratulate the authors on publishing the above-titled manuscript. The authors are targeting an important research question, and they used several tools to provide an answer from the 34 cancers they tested, including hepatocellular carcinoma. I have three comments- The title is not clear - "From pan-cancers to hepatocellular carcinoma"- it showed be instead testing 34 cancers, including hepatocellular carcinoma". We use "pan-cancer analysis", not from ..to, as stated. These 34 cancers should be stated in the introduction or the methods. I see some mentioned in the note under Figures 1 and 2. Informing the readers about them early is crucial. also, why they were selected. There is a bias in selecting references. Nearly most references (total 37) are by Chinese authors, may be you need to look into the broader English literature and include references from the USA, the UK, Canada, Europe, Japan, South Korea, Australia and New Zealand. Thank you." [Collapse]

Li JD, He RQ, Dang YW, Huang ZG, Xiong DD, Zhang L, Du XF, Chen G. Unveiling expression patterns, mechanisms, and therapeutic opportunities of transmembrane protein 106C: From pan-cancers to hepatocellular carcinoma. World J Gastrointest Oncol 2025; 17(2): 92437

"Cost-effective treatment strategies for liver fibrosis/cirrhosis are limited. Many clinical trials have shown that stem cells might ..." [Read more]

"Cost-effective treatment strategies for liver fibrosis/cirrhosis are limited. Many clinical trials have shown that stem cells might be a potential therapeutic approach here. This study presented the first bibliometric analysis of stem cell therapy for liver fibrosis/cirrhosis. This is useful information for future research on problems and trends in stem cell therapy for liver fibrosis/cirrhosis. " [Collapse]

Zhu WY, Li X, Xie JL, Lu Q, Ma YJ, Zhu ZJ, Liu J. Hotspots and trends in stem cell therapy for liver fibrosis and cirrhosis: A bibliometric analysis. World J Hepatol 2025; 17(1): 96105

"Fecal transplantation appears to be effective for refractory Crohn's disease, but please mention the intestinal flora before and after ..." [Read more]

"Fecal transplantation appears to be effective for refractory Crohn's disease, but please mention the intestinal flora before and after the procedure, and the short-chain fatty acids lactic acid, butyric acid, and acetic acid. Also, please describe contraindications for fecal transplantation for refractory Crohn's disease.How long do the effects of fecal transplants last?" [Collapse]

Ozbey D, Saribas S, Kocazeybek B. Gut microbiota in Crohn’s disease pathogenesis. World J Gastroenterol 2025; 31(6): 101266

"1 Ethics: Yes, the ethical approval form provided by the author that meets the requirements 2 Methods: Experimental method effective ..." [Read more]

"1 Ethics: Yes, the ethical approval form provided by the author that meets the requirements 2 Methods: Experimental method effective and well described by authors 3 Results: Yes, the results true and authentic. it is validated very well. 4 Figures and tables: Good quality and well constructive 5 Biostatistics: Yes, validated and perfect biostatistics data 6 References: Recent and relevant to the topic 7 Language: Good quality of language in article correctly, clearly and concisely without any grammatical and spelling mistakes. 8 Caveats or drawbacks: No obsvious caveats or drawbacks for the results noted" [Collapse]

Ba MQ, Zheng WL, Zhang YL, Zhang LL, Chen JJ, Ma J, Huang JL. Construction of a nomogram prediction model for early postoperative stoma complications of colorectal cancer. World J Gastrointest Surg 2025; 17(1): 100547

15075 items Read more >>

Peer-Reviewers and Manuscript Statistics

Editorial board members: 2763

Peer-reviewers: 27954

Manuscripts received today: 7

Manuscript reviews today: 14

Unhandled manuscripts today: 147

Active peer-reviewers today: 4099

Reviewer acceptance today: 29

Reviewer refusals today: 69

Total accepted manuscripts: 34684

Total rejected manuscripts: 40248

Total peer-reviewers: 3925034

Total submissions: 33001

Baishideng Publishing Group (BPG) publishes 47 peer-reviewed, open-access journals covering a broad range of topics in clinical medicine, as well as several topics in biochemistry and molecular biology, relevant to human health today.

BPG Journals

Reference Citation Analysis

BPG E-Books

BPG Blog

All Journal Articles

Nallakumarasamy A, Shrivastava S, Rangarajan RV, Jeyaraman N, Devadas AG, Ramasubramanian S, Jeyaraman M. Optimizing bone marrow harvesting sites for enhanced mesenchymal stem cell yield and efficacy in knee osteoarthritis treatment. World J Methodol 2025; 15(2): 101458

2025-06-20 | Browse: 1534 | Download: 202

Tüsüz Önata E, Özdemir Ö. Fecal microbiota transplantation in allergic diseases. World J Methodol 2025; 15(2): 101430

2025-06-20 | Browse: 1325 | Download: 170

Chauhan S, Chauhan R, Bhasin P, Bhasin M. Magnification: The game changer in dentistry. World J Methodol 2025; 15(2): 100937

2025-06-20 | Browse: 1427 | Download: 210

Sinha RK, Sinha S, Nishant P, Morya AK, Singh A. Telemedicine and public health–pearls and pitfalls. World J Methodol 2025; 15(2): 100632

2025-06-20 | Browse: 1206 | Download: 192

Deng L, Zhou R, Zhang X, Peng YH. Global trend of review articles focused on cardiopulmonary bypass: Perspectives from bibliometrics. World J Methodol 2025; 15(2): 100432

2025-06-20 | Browse: 1799 | Download: 237

Akhtar M, Nashwan AJ. Evaluating Wharton’s jelly-derived stem cell therapy in autism: Insights from a case study. World J Methodol 2025; 15(2): 100074

2025-06-20 | Browse: 1393 | Download: 184

Wu KA, Pottayil F, Jing C, Choudhury A, Anastasio AT. Surgical site soft tissue thickness as a predictor of complications following arthroplasty. World J Methodol 2025; 15(2): 99959

2025-06-20 | Browse: 1169 | Download: 162

Tayal V, Mandal A, Haque M I, Mishra A, Kalra BS, Roy V. Anticonvulsant potential of rosuvastatin in combination with carbamazepine and valproate in animal models of epilepsy. World J Methodol 2025; 15(2): 99580

2025-06-20 | Browse: 1303 | Download: 226

Cheng CY, Hao WR, Cheng TH. Advancements in diabetic retinopathy: Insights and future directions. World J Methodol 2025; 15(2): 99454

2025-06-20 | Browse: 1170 | Download: 171

Anand R, Nag DS, Patel R, Sharma P, Uppalapati VK, Singh UK. Comparative efficacy of hyperbaric bupivacaine vs hyperbaric ropivacaine in spinal anesthesia for cesarean section: A meta-analysis. World J Methodol 2025; 15(2): 99300

2025-06-20 | Browse: 1434 | Download: 228

Cheng CY, Hao WR, Cheng TH. Enhancing the outcomes of diabetic vitrectomy with pharmacological adjuvants. World J Methodol 2025; 15(2): 98912

2025-06-20 | Browse: 1069 | Download: 180

Grewal H, Dhillon G, Buddhavarapu V, Verma RK, Munjal RS, Sharma P, Sidhu G, Kashyap R, Surani S. Strategic insights of telehealth platforms and strengths, weaknesses, opportunities, and threats analysis of Amazon's clinical endeavors. World J Methodol 2025; 15(2): 98513

2025-06-20 | Browse: 1351 | Download: 205

Bećirović E, Bećirović M, Šegalo S, Bećirović A, Hadžić S, Ljuca K, Papić E, Ferhatbegović L, Ejubović M, Jagodić Ejubović A, Kovčić A, Šljivo A, Begagić E. Hemogram-derived ratios as prognostic markers for major adverse cardiovascular events in patients with non-ST-segment elevation myocardial infarction. World J Methodol 2025; 15(2): 98143

2025-06-20 | Browse: 1425 | Download: 294

Jeyaraman N, Jeyaraman M, Ramasubramanian S, Balaji S, Muthu S. Voices that matter: The impact of patient-reported outcome measures on clinical decision-making. World J Methodol 2025; 15(2): 98066

2025-06-20 | Browse: 1288 | Download: 203

Kolovou A, Gkougkoulias AN, Stefanou N, Samaila EM, Tsekoura M, Vlychou M, Matzaroglou C, Dailiana ZH. Musculoskeletal disorders in nursing staff. World J Methodol 2025; 15(2): 98043

2025-06-20 | Browse: 1094 | Download: 181

Muthu S, Vadranapu S. Variations in quantifying patient reported outcome measures to estimate treatment effect. World J Methodol 2025; 15(2): 97078

2025-06-20 | Browse: 1283 | Download: 199

Au SCL, Chong SSY. Prognostic factors in acute central retinal artery occlusion treated with hyperbaric oxygen: The Hong Kong study report number five. World J Methodol 2025; 15(2): 96777

2025-06-20 | Browse: 1366 | Download: 274

Jeyaraman N, Jeyaraman M, Ramasubramanian S, Balaji S, Nallakumarasamy A. Visualizing medicine: The case for implementing graphical abstracts in clinical reporting. World J Methodol 2025; 15(2): 95966

2025-06-20 | Browse: 1307 | Download: 189

Manjunatha BS, Handge KT, Shah VS, Al-Thobaiti YE, Pateel DGS. Immunohistochemical expression of matrix metalloproteinase-9 and 13 in oral squamous cell carcinoma and their role in predicting lymph node metastasis. World J Methodol 2025; 15(2): 94514

2025-06-20 | Browse: 1187 | Download: 235

Hetta HF, Ahmed R, Ramadan YN, Fathy H, Khorshid M, Mabrouk MM, Hashem M. Gut virome: New key players in the pathogenesis of inflammatory bowel disease. World J Methodol 2025; 15(2): 92592

2025-06-20 | Browse: 1492 | Download: 189

57382 items Read more >>

Featured Articles

Wei FF, Zhang J, Jia Z, Yao ZC, Chen CQ. Furmonertinib re-challenge for epidermal growth factor receptor-mutant lung adenocarcinoma after osimertinib-induced interstitial lung disease: A case report. World J Clin Oncol 2025; 16(3): 101766

2025-01-21 | Browse: 5 | Download: 13

Yan HC, Liu Y, Feng Y, Li JM, Sheng LM, Chen X, Xie YP, Li N. Efficacy of disitamab vedotin-containing therapy in metastatic colorectal cancer: A case report. World J Clin Oncol 2025; 16(3): 99527

2025-01-21 | Browse: 4 | Download: 0

2025-01-21 | Browse: 14 | Download: 0

Park H. Validation of the prognostic model for palliative radiotherapy in older patients with cancer. World J Clin Oncol 2025; 16(3): 101705

2025-01-21 | Browse: 4 | Download: 9

Huang Y, Wang XY, Huang JY, Huang ZW. Incorporation of human β-defensin-1 into immunoliposomes to facilitate targeted autophagy therapy of colon carcinoma. World J Clin Oncol 2025; 16(3): 101098

2025-01-21 | Browse: 3 | Download: 0

Chen XH, Xia W, Ma JB, Chen J, Hu J, Shi X, Yu JJ, Gong J, Liu L, Sun YA, Liu ZG. Rare mixed dementia: A case report. World J Radiol 2025; 17(1): 102579

2025-01-21 | Browse: 0 | Download: 0

2025-01-21 | Browse: 3 | Download: 0

Zhang HP, Bao L, Wu JJ, Zhou YQ. Independent risk factors for twin pregnancy adverse fetal outcomes before 28 gestational week by first trimester ultrasound screening. World J Radiol 2025; 17(1): 103111

2025-01-21 | Browse: 2 | Download: 0

Chang CC, Qiao LH, Zhang ZQ, Tian X, Zhang Y, Cheng WW, Wang X, Yang Q. High-resolution direct magnetic resonance imaging fistulography with hydrogen peroxide for diagnosing anorectal fistula: A preliminary retrospective study. World J Radiol 2025; 17(1): 101221

2025-01-21 | Browse: 3 | Download: 0

Fazlollahi F, Makary MS. Precision oncology: The role of minimally-invasive ablation therapy in the management of solid organ tumors. World J Radiol 2025; 17(1): 98618

2025-01-21 | Browse: 3 | Download: 7

Nie LJ, Cheng Z, He YX, Yan QH, Sun YH, Yang XY, Tian J, Zhu PF, Yu JY, Zhou HP, Zhou XQ. Role of duodenal mucosal resurfacing in controlling diabetes in rats. World J Diabetes 2025; 16(3): 102277

2025-01-21 | Browse: 9 | Download: 20

Liang LF, Zhao JQ, Wu YF, Chen HJ, Huang T, Lu XH. SMAD specific E3 ubiquitin protein ligase 1 accelerates diabetic macular edema progression by WNT inhibitory factor 1. World J Diabetes 2025; 16(3): 101328

2025-01-21 | Browse: 8 | Download: 25

Wu YK, Liu M, Zhou HL, He X, Wei J, Hua WH, Li HJ, Yuan QH, Xie YF. O-GlcNAc transferase regulates macrophage polarization in diabetic periodontitis: in vivo and in vitro study.. World J Diabetes 2025; 16(3): 95092

2025-01-21 | Browse: 7 | Download: 29

Luo YY, Ba XY, Wang L, Zhang YP, Xu H, Chen PQ, Zhang LB, Han J, Luo H. LEF1 influences diabetic retinopathy and retinal pigment epithelial cell ferroptosis via the miR-495-3p/GRP78 axis through lnc-MGC. World J Diabetes 2025; 16(3): 92003

2025-01-21 | Browse: 6 | Download: 26

2025-01-21 | Browse: 6 | Download: 12

Zhao JH, Wang JJ, Li YW. Granulomatosis with polyangiitis induced by the anti-programmed cell death-1 inhibitor tislelizumab: A case report. World J Clin Cases 2025; 13(15): 103239

2025-01-21 | Browse: 5 | Download: 15

2025-01-21 | Browse: 12 | Download: 1

Fan Y, Yu JH, Chen YH. Improved super-elastic Ti-Ni alloy wire for the angle class III patient with anterior open bite: A case report. World J Clin Cases 2025; 13(15): 101884

2025-01-21 | Browse: 6 | Download: 0

So H, Jang SI, Ko SW, Yoon SB, Lee YS, Bang S, Kim M, Choi HJ. Effect of brush rinse on the diagnostic accuracy of biliary stricture evaluation: A multicenter trial. World J Clin Cases 2025; 13(15): 99212

2025-01-21 | Browse: 5 | Download: 1

Boini A, Grasso V, Taher H, Gumbs AA. Artificial intelligence and the impact of multiomics on the reporting of case reports. World J Clin Cases 2025; 13(15): 101188

2025-01-21 | Browse: 4 | Download: 9

9184 items Read more >>

Keyword Search Published Articles Processes

Case report

2852

Case report

1462

Hepatocellular carcinoma

1386

Gastric cancer

965

Colorectal cancer

943

Inflammatory bowel disease

705

COVID-19

699

Prognosis

670

Liver transplantation

607

Treatment

552

Ulcerative colitis

547

Diagnosis

517

Helicobacter pylori

507

Crohn’s disease

501

Cirrhosis

475

Endoscopy

475

Meta-analysis

454

Magnetic resonance imaging

440

Pancreatic cancer

436

Surgery

423

66593 items Read more >>

Reader Comments

"As a colorectal surgeon interested in colorectal cancer and the microbiome, I found this study highly relevant. The authors ..." [Read more]

"As a colorectal surgeon interested in colorectal cancer and the microbiome, I found this study highly relevant. The authors effectively highlight differences in mucosa-associated colonic microbiota between colorectal cancer (CRC) and non-CRC patients in Indonesia. A key strength is the focus on mucosal rather than fecal microbiota, providing a clearer picture of the tumor microenvironment. The use of 16S rRNA sequencing with Oxford Nanopore Technologies enables detailed bacterial diversity analysis at the genus and species levels. The study confirms the increased presence of Fusobacterium nucleatum and Bacteroides fragilis in CRC patients, supporting the link between microbial dysbiosis and carcinogenesis. The diagnostic potential of these bacterial markers is particularly noteworthy. Further research with larger sample sizes and functional analyses, such as metagenomics or metabolomics, would enhance understanding of microbiota’s role in CRC. Additionally, while this study offers important insights for Asia, global research is needed to assess regional differences and their impact on CRC diagnostics and treatment. " [Collapse]

Darnindro N, Abdullah M, Sukartini N, Rumende CM, Pitarini A, Nursyirwan SA, Fauzi A, Makmun D, Nelwan EJ, Shatri H, Rinaldi I, Tanadi C. Differences in diversity and composition of mucosa-associated colonic microbiota in colorectal cancer and non-colorectal cancer in Indonesia. World J Gastroenterol 2025; 31(7): 100051

"The manuscript is very clinically relevant. Here's a suggestion. Authors should provide the data on patients undergoing colonoscopy ..." [Read more]

"The manuscript is very clinically relevant. Here's a suggestion. Authors should provide the data on patients undergoing colonoscopy prior to capsule endoscopy examination. The retention rate of capsule endoscopy at 72 hours was 42.2%, which is still relatively high.It helps to reduce capsule retention in the colon after colonoscopy examination. " [Collapse]

O'Hara FJ, Costigan C, McNamara D. Extended 72-hour patency capsule protocol improves functional patency rates in high-risk patients undergoing capsule endoscopy. World J Gastrointest Endosc 2024; 16(12): 661-667

"This case report highlights the importance of en-bloc resection without fragmentation during endoscopic procedures and the challenges ..." [Read more]

"This case report highlights the importance of en-bloc resection without fragmentation during endoscopic procedures and the challenges of endoscopic treatment for anal canal cancer. Traditionally, anal lesions have been primarily managed by surgeons, but ESD-related technique is performed mainly by the gastrointestinal endoscopists of internal medicine. Future collaboration between internal medicine and surgery departments will be crucial. Surgery for anal cancer can significantly decrease patients' quality of life, which is why the authors' dedication to endoscopic treatment and follow-up is commendable. Anal canal cancer is rare, and it will be essential to determine which cases are suitable for endoscopic therapy in the future. With the increasing prevalence of inflammatory bowel diseases in Asian regions, a rise in anal cancer cases associated with conditions like Crohn's disease is anticipated. Further case reports in this field are desirable. " [Collapse]

Kinoshita M, Maruyama T, Hike S, Hirosuna T, Kainuma S, Kinoshita K, Nakano A, Ohira G, Uesato M, Matsubara H. Complete resection of recurrent anal canal cancer using endoscopic submucosal dissection and transanal resection: A case report. World J Gastrointest Endosc 2025; 17(1): 101119

"This is an excellent and insightful article. The authors have provided a comprehensive overview of the most impactful studies in the ..." [Read more]

"This is an excellent and insightful article. The authors have provided a comprehensive overview of the most impactful studies in the field of gastrointestinal endoscopy. It has greatly enhanced my understanding of the current research landscape and has inspired me to define more focused and meaningful directions for my own research in this area. " [Collapse]

Sui J, Luo JS, Xiong C, Tang CY, Peng YH, Zhou R. Bibliometric analysis on the top one hundred cited studies on gastrointestinal endoscopy. World J Gastrointest Endosc 2025; 17(1): 100219

"This paper examines the differences in proficiency of AI tools for IBD patients and is considered a critical study for the inevitable ..." [Read more]

"This paper examines the differences in proficiency of AI tools for IBD patients and is considered a critical study for the inevitable future utilization of large language models in healthcare. However, it is merely a comparative study of large language models, and it remains unclear whether it contributes to improving IBD patients' literacy. Regarding patient education, Crohn's disease and ulcerative colitis belong to different categories, making it challenging to evaluate IBD as a whole comprehensively. Separate evaluations for ulcerative colitis and Crohn's disease patients would be preferable. Furthermore, large language models alone are insufficient for shared decision-making that considers patients' social backgrounds for treatment selection, including biological agents (especially for Crohn's disease). Simply improving knowledge on several items through large language models may not be enough for clinical application. Future evaluations using large language models should address these points. " [Collapse]

Zhang Y, Wan XH, Kong QZ, Liu H, Liu J, Guo J, Yang XY, Zuo XL, Li YQ. Evaluating large language models as patient education tools for inflammatory bowel disease: A comparative study. World J Gastroenterol 2025; 31(6): 102090

"Dear editor, this is a review that summarizes the most recent evidence focused on the safety of the peroral endoscopic myotomy (POEM). ..." [Read more]

"Dear editor, this is a review that summarizes the most recent evidence focused on the safety of the peroral endoscopic myotomy (POEM). The manuscript is well written. However, I found some inaccuracies in the background. The style, language and grammar are appropriate. Since there are no figures or tables in the paper I answered no to the dedicated questions. Although the safety of POEM is well explained, superficial informations were provided on the precision and the post-procedural management. Therefore, I would focus the article mainly on the safety, explaining better the post-procedural management. " [Collapse]

Christodoulidis G, Tsagkidou K, Koumarelas KE, Kouliou MN. Advances and challenges in peroral endoscopic myotomy: Safety, precision, and post-procedure management. World J Gastroenterol 2025; 31(5): 97574

"This case is an extensively worked-up and well-written report. Best regards to the team. Stroke is not a clear-cut biophysics in ..." [Read more]

"This case is an extensively worked-up and well-written report. Best regards to the team. Stroke is not a clear-cut biophysics in neurology, with challenges in the clinical-radiological correlation encountered so often in clinical practice. As in this case, the work-up in SPECT could not convincingly determine theexact biomechanism of the clinical phenomena. However, it opened up information for future scopes of research into lacunar strokes. DSA, functional MRI, and Perfusion mismatch studies can also help in this type of situations. In contrast, the treatment is fairly less complicated in lacunar stroke. " [Collapse]

Tsai YH, Chen YH, Chao TC, Lin LF, Chang ST. New type of lacunar stroke presenting in brain perfusion images: A case report. World J Neurol 2024; 10(1): 98672

"Fu et al.'s recent study published in the World Journal of Psychiatry examines a complex connection between parenting stress, various ..." [Read more]

"Fu et al.'s recent study published in the World Journal of Psychiatry examines a complex connection between parenting stress, various family parenting styles, and the behavioral and emotional challenges that children experience. This study highlights the need for appropriate emotional management during the preschool years, demonstrating how differences in parental stress may have a significant impact on children's early emotional health. The analytical strength of this study is really impressive. The authors use structural equation modeling (SEM) to give a detailed examination of how different parenting styles mediate the relationships between these factors. Moreover, comprehensive questionnaire data collection contributes to a better understanding of family dynamics in a variety of environments. According to the findings, parents report high levels of stress, which suggests that they face constant challenges. The study discovers a link between "hostile/coercive" parenting and problem behaviors in children, revealing the deleterious effects of negative strategies for parenting. This conclusion is consistent with previous research, which emphasizes the importance of understanding how inadequate parenting may lead to behavioral problems in children. Conversely, the negative connection with "supportive/engaged" parenting implies that positive approaches might provide large protective benefits, emphasizing the importance of specific treatments. Besides, this study emphasizes how parenting styles serve as mediators in the relationship between parental stress and children's emotional health. The data show a 28.99% mediation impact, indicating that how parents handle stress influences the behaviors of their kids through their strategies for parenting. This finding not only strengthens the foundation for designing personalized therapies, but it also emphasizes the important need to improve parental practices. Also, the study points out the importance of providing parents with evidence-based strategies for managing their emotional health, with a focus on both parental and child well-being. The study aims to establish a caring environment for preschoolers by giving practical ways to reduce stress and promoting positive parenting behaviors. It focuses on the broader impacts of various parenting styles, implying that investing in parental support systems is important for enhancing children's mental health and promoting total family happiness. This perspective is consistent with current trends in mental health initiatives and requires a comprehensive effort to address families' emotional needs, supplying the framework for future research in this important area. Although Fu et al.'s work contributes significantly to our understanding of the link between parental stress and children's behavior, future research might profit from using a longitudinal strategy. Such an approach might allow researchers to investigate the changing dynamics of parental stress and child behavior over time, leading to a more comprehensive explanation of their causal relationships. Longitudinal studies may track how changes in parental stress affect the growth path of children's behavior by following the same set of participants at different points in time. This method not only gives a more in-depth understanding of these dynamics, but it also identifies potential mediators and moderators, offering light on the underlying reasons of the connections. Finally, this strategy may help us understand how the family environment affects children's developmental achievement. " [Collapse]

Fu ZW, Li YJ, Yu R, Guo RQ, Gao LX, Zhao SX. Relationship between parenting stress and behavioral and emotional problems in preschool children: A mediation effect analysis. World J Psychiatry 2025; 15(1): 100068

"There is a need for non-invasive methods of evaluating mucosal healing in the small bowel. This study applies the principles of ..." [Read more]

"There is a need for non-invasive methods of evaluating mucosal healing in the small bowel. This study applies the principles of radiomics using small bowel CTE to develop a predictive normogram capable of predicting mucosal healing. Despite the study's stated limitations, it adds to the current literature, and extends the emerging field of radiomics in Crohn's disease. " [Collapse]

Ding H, Fang YY, Fan WJ, Zhang CY, Wang SF, Hu J, Han W, Mei Q. Computed tomography enterography-based radiomics for assessing mucosal healing in patients with small bowel Crohn's disease. World J Gastroenterol 2025; 31(3): 102283

"The article presents a strong case for the use of endoscopic ultrasound-guided gastroenterostomy (EUS-GE) in managing gastric outlet ..." [Read more]

"The article presents a strong case for the use of endoscopic ultrasound-guided gastroenterostomy (EUS-GE) in managing gastric outlet obstruction (GOO). However, a few points could be clarified to strengthen its conclusions. Specifically, it would be helpful to elaborate on the inclusion or exclusion criteria for patient selection, as well as provide data on long-term outcomes like stent patency and recurrence rates. Additionally, discussing the learning curve associated with EUS-GE and the level of expertise required for its successful implementation would offer valuable insight for broader clinical adoption. " [Collapse]

Jagielski M. Endoscopic ultrasound guided-gastroenterostomy is the best choice in the treatment of gastric outlet obstruction. World J Gastrointest Endosc 2024; 16(12): 691-693

"The manuscript is very interesting. Global burden of human disorders caused by parasites is high. The topic is hot in selected areas. ..." [Read more]

"The manuscript is very interesting. Global burden of human disorders caused by parasites is high. The topic is hot in selected areas. Those areas include not only Asia or Africa, but some parts of Eastern and Central Europe. I recommend to read the article for specialists in Hepatology, Liver surgery, including liver transplantation, Epademiology and Infectious Diuseases. " [Collapse]

Shahid Y, Emman B, Abid S. Liver parasites: A global endemic and journey from infestation to intervention. World J Gastroenterol 2025; 31(1): 101360

"This editorial pointed out the connection between adipose tissue and intestinal bacteria in Crohn's disease (CD). It is an interesting ..." [Read more]

"This editorial pointed out the connection between adipose tissue and intestinal bacteria in Crohn's disease (CD). It is an interesting paper. The authors found that Clostridium innocuum migrates to adjacent adipose tissue and remains "trapped" in the fat. As a result, immune cell migration and macrophage differentiation increase, leading to fibrosis, narrowing, and, eventually, the formation of creeping fat. Although the main cytokine release is mainly TNFα and IL-6 in adipocytes, the cytokine profile changes over time, especially in fibrosis, may be related to IL-17, and the dominant cytokines will change from IL-12 to IL-23, as previously pointed out. It is interesting to evaluate the aging adipose tissue in CD. However, it is difficult to determine the actual time of onset in patients with CD, and it is challenging to evaluate this issue. " [Collapse]

Quaglio AE, Magro DO, Imbrizi M, De Oliveira EC, Di Stasi LC, Sassaki LY. Creeping fat and gut microbiota in Crohn’s disease. World J Gastroenterol 2025; 31(1): 102042

"The authors provide evidence supporting the efficacy of serum-free cultured human umbilical cord mesenchymal stem cells (N-hUCMSCs) ..." [Read more]

"The authors provide evidence supporting the efficacy of serum-free cultured human umbilical cord mesenchymal stem cells (N-hUCMSCs) in treating knee osteoarthritis (OA). However, as the results indicate that the therapeutic effects of N-hUCMSCs, serum-cultured hUCMSCs (S-hUCMSCs), and hyaluronic acid (HA) are comparable, the rationale for prioritizing N-hUCMSCs warrants further exploration, particularly in comparison to the well-established use of HA. There are also issues with data quality and clarity 1.The study administered three injections (at 2, 4, and 6 weeks after model establishment). However, the rationale for this dosing schedule is not provided. HA dosing is not described in the manuscript. 2.The source of the N-hUCMSCs and S-hUCMSCs should be disclosed. Were these cells derived from the same donor? If not, what were the baseline characteristics of each donor (e.g., age, health status)? Such details are critical, as MSC functionality can vary significantly based on donor conditions. 3.Some results, such as those described in Figure 1 and the observation that “Uneven chondrocyte thickness, disorganized cartilage structure, and increased clefts were more pronounced in the model control group than in the blank control group,” are inappropriately placed in the methods section. These descriptions should be moved to the results section. 4. Figure 3c and 3d: Both graphs have the same y-axis label, but according to the results section, one should represent IL-6 and the other IL-1β. Figure 4a and 4b: These panels illustrate hematoxylin-eosin (HE) staining for the model and control groups. However, the HE results for the treatment groups (N-hUCMSCs, S-hUCMSCs, and HA) are missing. Including these results would provide a clearer comparison of treatment effects. 5.Figure 4d: The manuscript mentions that “The Mankin scores were significantly lower in the experimental group than in the model control group (P < 0.05),” but this result is not adequately represented in the figure. " [Collapse]

Xiao KZ, Liao G, Huang GY, Huang YL, Gu RH. Efficacy of serum-free cultured human umbilical cord mesenchymal stem cells in the treatment of knee osteoarthritis in mice. World J Stem Cells 2024; 16(11): 944-955

"he significant impact of surgical approaches on male sexual dysfunction after rectal cancer surgery is highlighted by both this letter ..." [Read more]

"he significant impact of surgical approaches on male sexual dysfunction after rectal cancer surgery is highlighted by both this letter to the editor and the latest study by Numata et al. published in Annals of Surgery1). Damage to the autonomic nervous system during rectal cancer surgery is a major cause of sexual dysfunction, with problems such as ejaculatory dysfunction, erectile dysfunction, and sexual dysfunction commonly reported. These complications are particularly common with open surgery, and previous research has also shown that the incidence of sexual dysfunction following surgery is high. However, advances in surgical techniques such as robotic surgery are expected to reduce these complications. The LANDMARC Study provided convincing evidence that robotic surgery significantly reduces the incidence of postoperative sexual dysfunction compared to laparoscopic surgery. The incidence of ejaculatory dysfunction at 12 months postoperatively was 25% in robotic surgery patients compared to 40.9% in laparoscopic surgery patients. The incidence of sexual dysfunction was 17.8% and 29%, respectively. This letter to editor alos emphasized the importance of accurate surgical technique and knowledge of pelvic nerve anatomy. It also discussed the benefits of new techniques such as robotic surgery and transanal total mesorectal excision (Ta-TME), as well as the use of intraoperative pelvic nerve monitoring. These advances enhance nerve preservation, reduce complications, and improve patients' postoperative quality of life. These findings highlight the need to adapt innovative surgical techniques in rectal cancer treatment to minimize adverse effects on sexual health while maintaining oncologic effectiveness. 1) Numata, Masakatsu, et al. "Prospective Multicenter Comprehensive Survey on Male Sexual Dysfunction following Laparoscopic, Robotic, and Transanal Approaches for Rectal Cancer (the LANDMARC Study)." Annals of Surgery: 10-1097 " [Collapse]

Kolokotronis T, Pantelis D. Urinary and sexual dysfunction after rectal cancer surgery: A surgical challenge. World J Gastroenterol 2024; 30(47): 5081-5085

"since the patient also had general anesthesia, it should be clairifed to whihc degree analgesics given for the procedure prevented ..." [Read more]

"since the patient also had general anesthesia, it should be clairifed to whihc degree analgesics given for the procedure prevented the patient from experienceing severe pain xxxx xx x x x x x x x x x x x x x x x x x x x x x x xx x x x x x xx " [Collapse]

Chen KH, Kang MY, Chang YT, Huang SY, Wu YS. Enhancing postoperative pain control by surgically-initiated rectus sheath block in abdominal aortic aneurysm open repair: A case report. World J Clin Cases 2025; 13(6): 100673

"The novelty of the topic is very important, suitable for fine rather than too broad content. The interpretation of statistical results ..." [Read more]

"The novelty of the topic is very important, suitable for fine rather than too broad content. The interpretation of statistical results needs to be rigorous, correlation does not mean causation, and the HR presented may be inaccurate. The discussion needs to be tightly focused on the results and not extend to other unwarranted conclusions. " [Collapse]

Chen DQ, Wu YX, Zhang YX, Yang HL, Huang HH, Lv JY, Xiao Q. Sarcopenia-associated factors and their bone mineral density levels in middle-aged and elderly male type 2 diabetes patients. World J Diabetes 2024; 15(12): 2285-2292

"I would like to commend the authors for their comprehensive analysis of the complex interplay between gut microbiota, mesenteric ..." [Read more]

"I would like to commend the authors for their comprehensive analysis of the complex interplay between gut microbiota, mesenteric adipose tissue (MAT), and creeping fat (CF) in the context of Crohn’s disease (CD). The manuscript provides a valuable contribution to the field. The article meticulously elucidates the profound clinical significance of the interplay between the gut microbiota and MAT/CF. The authors have not only reviewed the current body of knowledge but have also contributed novel insights into the role of MAT and CF in shaping CD phenotypes and treatment strategies.The structure of the letter is well-organized, making it easy to follow the authors' line of reasoning. The abstract succinctly captures the essence of the study, and the core tip effectively highlights the main takeaways for the reader.The exploration of fecal microbiota transplantation (FMT) as a therapeutic strategy is both timely and relevant. The authors have successfully linked the current understanding of microbial imbalances to potential clinical applications, which could influence future treatment protocols for CD. In conclusion, Hasnaoui et al. have provided a thought-provoking analysis of the role of gut microbiota and MAT/CF in CD. Their work not only advances our understanding of the disease but also offers promising avenues for therapeutic intervention. " [Collapse]

Hasnaoui A, Trigui R, Giuffrida M. Gut microbiota and mesenteric adipose tissue interactions in shaping phenotypes and treatment strategies for Crohn’s disease. World J Gastroenterol 2024; 30(46): 4969-4976

"The author suggests to use in all diabetic patients an interesting technique, the” body surface gastric mapping” (BSGM), to detect ..." [Read more]

"The author suggests to use in all diabetic patients an interesting technique, the” body surface gastric mapping” (BSGM), to detect the onset of gastric dysmotility precursor of gastroparesis, instead of invasive procedures, as gastroscopy, manometry, emptying of radiopaque markers or radioactive bolus and breath tests . The idea is interesting , but there are some observations to make. First of all the author forgot a simple, not invasive, physiologic and reliable method to measure gastric emptying, that is real-time ultrasonography, which allows the use of a normal solid–liquid meal and gives an immediate result (1). Furthermore the author did not take into account the fact that, as indicated in figure 1 of ref. 4, the cause of delayed gastric emptying in gastroparesis may be also due, not only to antral dysmotility detectable with BSGM, but also to impaired pyloric relaxation upon arrival of antral peristalsis (pylorospasm) and, sometimes, to dysmotility of duodenum, which does not accept the bolus coming from the stomach. The pylorospasm, which was observed in 14 of 24 diabetics, by Mearin et al (2) forms part of the widespread disruption of gut motility that affects some patients with diabetes. Unfortunately these pyloric and duodenal motor abnormalities are not detected by the technique of BSGM, which could find a normal antral motility, giving the impression that everything is OK, while the gastric emptying is already delayed. Therefore I would suggest to monitor the diabetic patients with the real-time ultrasonography, which is able to detect also a minimal delay in gastric emptying harbinger of gastroparesis, and, if the gastric emptying is delayed, then perform the BSGM, to see if the cause of the slowing is due to antral dysmotility. If the latter examination is negative, then the cause of delayed gastric emptying shoul be pylorospasm or duodenal dysmotility. REFERENCES 1) Bolondi L, Bortolotti M, Santi V, Calletti T, Gaiani S, Labò G. Measurement of gastric emptying time by real-time ultrasonography. Gastroenterology. 1985 Oct; 89(4):752-9.PMID:3896910. 2) Mearin F, Camilleri M, Malagelada JR. Pyloric dysfunction in diabetics with recurrent nausea and vomiting. Gastroenterology. 1986 Jun;90(6):1919-25. doi: 10.1016/0016-5085(86)90262-3. PMID: 3699409 " [Collapse]

Mori H. Early detection and intervention in diabetic gastroparesis: Role of body surface gastric mapping. World J Gastroenterol 2024; 30(45): 4836-4838

"This article presents a case report of air embolism occurring during endoscopic retrograde cholangiopancreatography (ERCP), ..." [Read more]

"This article presents a case report of air embolism occurring during endoscopic retrograde cholangiopancreatography (ERCP), emphasizing the necessity for gastroenterologists to maintain a high level of vigilance regarding this potential complication during such procedures. While ERCP is a widely used and effective diagnostic and therapeutic technique, air embolism represents a serious complication that can significantly jeopardize patient health. Consequently, this article not only reviews pertinent cases and analyzes the mechanisms, clinical manifestations, and countermeasures associated with air embolism but also underscores the importance of preventive measures that medical staff should implement to minimize the incidence of such complications during ERCP. The aim of this article is to provide a comprehensive overview of relevant knowledge, thereby enabling medical professionals to better understand and address this issue, ultimately enhancing the safety and effectiveness of clinical operations. " [Collapse]

Li JH, Luo ZK, Zhang Y, Lu TT, Deng Y, Shu RT, Yu H. Systemic air embolism associated with endoscopic retrograde cholangiopancreatography: A case report. World J Gastrointest Endosc 2024; 16(11): 617-622

"Exercise during pregnancy improve organ development in offspring with gestational diabetes mellitus Shengju Chen, Hangming Fan, Yu ..." [Read more]

Tang YB, Wang LS, Wu YH, Zhang LX, Hu LY, Wu Q, Zhou ML, Liang ZX. Effect of exercise during pregnancy on offspring development through ameliorating high glucose and hypoxia in gestational diabetes mellitus. World J Diabetes 2024; 15(11): 2203-2219

886 items Read more >>

Write to the Help Desk