Publisher Login
Manuscript Statistics
1
2
2024-09-30 | Browse: 72 | Download: 0
3
4
5
6
2024-09-30 | Browse: 58 | Download: 0
7
8
2024-09-30 | Browse: 64 | Download: 0
9
10
11
12
2024-09-29 | Browse: 83 | Download: 0
13
14
2024-09-29 | Browse: 68 | Download: 0
15
16
17
18
19
2024-09-29 | Browse: 79 | Download: 0
20
2024-09-29 | Browse: 61 | Download: 0
380 items Read more >>
1
"The online subssion system is user-friendly, and the peer review is quick and efficient. I'm satisfied with all. In a word, the journal ..."
[Read more]
"The online subssion system is user-friendly, and the peer review is quick and efficient. I'm satisfied with all. In a word, the journal is really excellent, both the content and the editors are impeccable, which is really a leader in the industry. Each issue can brings me new inspiration and thinking. "
[Collapse]
Wang XH, Chen FF, Pan J, Jiang YF, Yao MY, Mao JL, Xu YF. Impact of fast-track surgery on perioperative care in patients undergoing hepatobiliary surgery. World J Gastrointest Surg 2024; 16(10): 3155-3162
2
"First of all, I am honored to have my research published in F6publishing. I am very satisfied with the overall experience with the ..."
[Read more]
"First of all, I am honored to have my research published in F6publishing. I am very satisfied with the overall experience with the journal platform and am deeply impressed by the efficiency and professionalism throughout the review and publication process. The editorial team at F6publishing demonstrated a high level of academic expertise and a rigorous attitude. They provided detailed and constructive feedback during the review process, which greatly helped me improve and refine my paper. The review process was transparent and swift, significantly reducing the manuscript processing time, allowing me to see my work published in a relatively short time. Furthermore, the F6publishing platform itself is highly convenient and user-friendly. From manuscript submission to final publication, the entire process was supported by professional services. The platform’s workflow was clear, and the interface was simple and smooth, greatly enhancing the efficiency of manuscript handling. Overall, I am very satisfied with my publication experience at F6publishing and look forward to more opportunities for collaboration in future academic endeavors. I also highly recommend other scholars to submit their work to F6publishing, as it provides an excellent platform for academic exchange. "
[Collapse]
Yang HT, Wang FR, He N, She YH, Du YY, Shi WG, Yang J, Chen G, Zhang SZ, Cui F, Long B, Yu ZY, Zhu JM, Zhang GY. Massive simultaneous hepatic and renal perivascular epithelioid cell tumor benefitted from surgery and everolimus treatment: A case report. World J Gastrointest Surg 2024; 16(10): 3334-3342
3
"It is very lucky to submit articles to your journal. All the peer-review process is both very professional and helpful. And the ..."
[Read more]
"It is very lucky to submit articles to your journal. All the peer-review process is both very professional and helpful. And the response or comments provided by them are prompt. But I think it takes a little longer to find a proper reviewer. And we hope in the future you can find more reviewers in a comparatively short time. "
[Collapse]
Lv BJ, Zuo HJ, Li QF, Huang FF, Zhang T, Huang RX, Zheng SJ, Wan WJ, Hu K. Retinal microcirculation changes in prediabetic patients with short-term increased blood glucose using optical coherence tomography angiography. World J Radiol 2024; 16(9): 407-417
4
"I would speed up all the steps. The process is perfect, however that the time was too long, especially for the first review. ..."
[Read more]
"I would speed up all the steps. The process is perfect, however that the time was too long, especially for the first review. Unfortunately, the references updates could become old as the process continue. The reviewers should be less, but more motivated! Moreover, the English editing services should be encouraged to promote discounts for authors. "
[Collapse]
Bencini L, Annecchiarico M, Farsi M, Bartolini I, Mirasolo V, Guerra F, Coratti A. Minimally invasive surgical approach to pancreatic malignancies. World J Gastrointest Oncol 2015; 7(12): 411-421
5
"I would speed up all the steps. The process is perfect, however that the time was too long, especially for the first review. ..."
[Read more]
"I would speed up all the steps. The process is perfect, however that the time was too long, especially for the first review. Unfortunately, the references updates could become old as the process continue. The reviewers should be less, but more motivated! Moreover, the English editing services should be encouraged to promote discounts for authors. "
[Collapse]
Bencini L, Moraldi L, Bartolini I, Coratti A. Esophageal surgery in minimally invasive era. World J Gastrointest Surg 2016; 8(1): 52-64
6
"I would speed up all the steps. The process is perfect, however that the time was too long, especially for the first review. ..."
[Read more]
"I would speed up all the steps. The process is perfect, however that the time was too long, especially for the first review. Unfortunately, the references updates could become old as the process continue. The reviewers should be less, but more motivated! Moreover, the English editing services should be encouraged to promote discounts for authors. "
[Collapse]
Bencini L, Tommasi C, Manetti R, Farsi M. Modern approach to cholecysto-choledocholithiasis. World J Gastrointest Endosc 2014; 6(2): 32-40
7
"I would speed up all the steps. The process is perfect, however that the time was too long, especially for the first review. ..."
[Read more]
"I would speed up all the steps. The process is perfect, however that the time was too long, especially for the first review. Unfortunately, the references updates could become old as the process continue. The reviewers should be less, but more motivated! Moreover, the English editing services should be encouraged to promote discounts for authors. "
[Collapse]
Bencini L, Bernini M, Farsi M. Laparoscopic approach to gastrointestinal malignancies: Toward the future with caution. World J Gastroenterol 2014; 20(7): 1777-1789
8
"We thank the editor, reviewers and publication team for considering our work for publication in their esteemed journal and for the ..."
[Read more]
"We thank the editor, reviewers and publication team for considering our work for publication in their esteemed journal and for the help in improving article quality and wonderful publishing experience.I am eager to explore more opportunities to work together. Thank you once again for the wonderful opportunity and your continued support. "
[Collapse]
Liu D, Li SC. Nursing of a patient with multiple primary cancers: A case report and review of literature. World J Clin Oncol 2024; 15(10): 1315-1323
9
"Thank you for accepting and publishing our article. Although the review period is a little bit of long, APC fee is too expensive, ..."
[Read more]
"Thank you for accepting and publishing our article. Although the review period is a little bit of long, APC fee is too expensive, others are perfect. Overall, we are all satisfied with the whole submitting, revising and proofing process. We do sincerely hope your journal can be indexed in SCI soon on the future. "
[Collapse]
Lin RT, Liu PK, Chang CW, Cheng KC, Chen KJ, Chang YC. Behcet's disease-related panuveitis following COVID-19 vaccination: A case report. World J Radiol 2024; 16(9): 460-465
10
"It is a great honor to have our manuscript published in such an excellent journal. The publication process was very smooth, thanks ..."
[Read more]
"It is a great honor to have our manuscript published in such an excellent journal. The publication process was very smooth, thanks to the reviewers' comments, which improved the quality of the article. Thank you very much for the help of the editorial department, so that our article can be published smoothly "
[Collapse]
He YG, Zhang LY, Li J, Wang Z, Zhao CY, Zheng L, Huang XB. Conversion therapy in advanced perihilar cholangiocarcinoma based on patient-derived organoids: A case report. World J Gastrointest Oncol 2024; 16(10): 4274-4280
11
"Dear Editor, I am writing to express my profound satisfaction with my recent submission experience to your esteemed journal. First ..."
[Read more]
"Dear Editor, I am writing to express my profound satisfaction with my recent submission experience to your esteemed journal. First and foremost, I would like to extend my heartfelt thanks to the entire editorial team for the meticulous attention and professional handling they provided to my manuscript. From the initial submission of the draft to its eventual acceptance for publication, the entire process was not only efficient but also transparent, affording me a deeper understanding and respect for the academic publishing process. Looking forward to more opportunities for collaboration in the future to jointly advance scholarly research. Wishing you success in your work and continued prosperity for the journal. Sincerely, Yihuai He "
[Collapse]
Liang MX, Chen Y, He Y, He YH. Journey to diagnosis: An unfinished exploration of IgG4-related sclerosing cholangitis. World J Clin Cases 2024; 12(33): 6608-6612
12
"The editorial staff showed Excellent cooperation, remarkable skills and impeccable communication all of these are fundamental for ..."
[Read more]
"The editorial staff showed Excellent cooperation, remarkable skills and impeccable communication all of these are fundamental for the publishing procedure to flow without problems. The reviewers comments and corrections were spot on and helped to better the article considerably. We would like to thank everyone for a job well done and we are looking forward for the next paper "
[Collapse]
Michailidis A, Panos A, Samoladas E, Dimou G, Mingou G, Kosmoliaptsis P, Arvaniti M, Giankoulof C, Petsatodis E. Cryoablation of osteoid osteomas: Is it a valid treatment option? World J Radiol 2024; 16(9): 389-397
13
"The review process is smooth. I really appreciate and enjoy working with BPG. Looking forward to more invites . I am highly interested ..."
[Read more]
"The review process is smooth. I really appreciate and enjoy working with BPG. Looking forward to more invites . I am highly interested in GI and hepatology journals . Please let me know iif I can be sent invites for these manuscripts. The editors were friendly and were quick to response. The reviewer's comments were very insightful and have set up the manuscript for success. "
[Collapse]
Singh A, Khanna T, Mahendru D, Kahlon J, Kumar V, Sohal A, Yang J. Insights into renal and urological complications of inflammatory bowel disease. World J Nephrol 2024; 13(3): 96574
14
"I am thrilled to announce the earliest publication of my research on regenerative modalities for knee osteoarthritis. This milestone ..."
[Read more]
"I am thrilled to announce the earliest publication of my research on regenerative modalities for knee osteoarthritis. This milestone represents countless hours of dedication and hard work. I am grateful for the support and collaboration from my colleagues and mentors. This achievement motivates me to continue advancing in this vital field. Thank you for your encouragement! "
[Collapse]
Jeyaraman M, Jeyaraman N, Ramasubramanian S, Balaji S. Navigating the ethical terrain: Off-label and experimental treatments in medical case reports. World J Methodol 2025; 15(1): 94833
15
"I am thrilled to announce the earliest publication of my research on regenerative modalities for knee osteoarthritis. This milestone ..."
[Read more]
"I am thrilled to announce the earliest publication of my research on regenerative modalities for knee osteoarthritis. This milestone represents countless hours of dedication and hard work. I am grateful for the support and collaboration from my colleagues and mentors. This achievement motivates me to continue advancing in this vital field. Thank you for your encouragement! "
[Collapse]
Muthu S, Mogulesh C, Viswanathan VK, Jeyaraman N, Pai SN, Jeyaraman M, Khanna M. Is cellular therapy beneficial in management of rotator cuff tears? Meta-analysis of comparative clinical studies. World J Meta-Anal 2022; 10(3): 162-176
16
"I am thrilled to announce the earliest publication of my research on regenerative modalities for knee osteoarthritis. This milestone ..."
[Read more]
"I am thrilled to announce the earliest publication of my research on regenerative modalities for knee osteoarthritis. This milestone represents countless hours of dedication and hard work. I am grateful for the support and collaboration from my colleagues and mentors. This achievement motivates me to continue advancing in this vital field. Thank you for your encouragement! "
[Collapse]
Jeyaraman N, Jeyaraman M, Ramasubramanian S, Balaji S, Muthu S. Beyond statistical significance: Embracing minimal clinically important difference for better patient care. World J Methodol 2025; 15(1): 97814
17
"The peer-review feedback process should be more timely, fluid and transparent, and it is unnecessary and confusing to require excessive ..."
[Read more]
"The peer-review feedback process should be more timely, fluid and transparent, and it is unnecessary and confusing to require excessive editing of manuscript text and image formatting before final acceptance of the manuscript for publication. Each stage of the process from manuscript submission to publication should be made clearer, e.g., the manuscript may go through the process of submission, quality checking, initial review by the editor, external review, revision by the authors and further external review, and acceptance, proof, and official publication, which should be rigorous, standardized, and clear, and redundant manuscript status fields in the submission system could be deleted. Anyway, thank you for your contribution! "
[Collapse]
Zheng ZQ, Cai DH, Song YF. Identification of immune feature genes and intercellular profiles in diabetic cardiomyopathy. World J Diabetes 2024; 15(10): 2093-2110
18
"Thank you for World Journal of Diabetes accepted our manuscript(Potential mechanism of teneligliptin in the treatment of diabetic ..."
[Read more]
"Thank you for World Journal of Diabetes accepted our manuscript(Potential mechanism of teneligliptin in the treatment of diabetic cardiomyopathy No.94927). Unfortunately, we found that the author information in the final PDF version did not match the content in the revised manuscript. Our hospital apartment has two names, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), but the apartment of Dr. Qing-Yuan Wu and Lu-Sha Cen(corresponding author) are missing the content in parentheses. This article is very important to us because it relates to the promotion of young doctors. I am very sorry to wonder if you could update”The First Affiliated Hospital of Zhejiang Chinese Medical University” to “The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)”, we just want to add one piece of information rather than modify it. WJD is a great journal and we did not want to lose this article. We have sent an email to the editorial department, but have not received a reply. I am so sorry for our omission and look forward to receiving your reply. "
[Collapse]
Guo J, Cao Y, Wu QY, Cen LS. Potential mechanism of teneligliptin in the treatment of diabetic cardiomyopathy. World J Diabetes 2024; 15(10): 2002-2005
19
"The review process was quite lengthy, but it greatly improved the quality of my manuscript. I truly appreciate the editor's commitment ..."
[Read more]
"The review process was quite lengthy, but it greatly improved the quality of my manuscript. I truly appreciate the editor's commitment to upholding the high standards of the esteemed WJD journal. Given its strong reputation, I am enthusiastic about submitting more and more of my work to WJD in the future. "
[Collapse]
Chakraborty R, Mukherjee AK, Bala A. Interleukin-35: A key player managing pre-diabetes and chronic inflammatory type 1 autoimmune diabetes. World J Diabetes 2024; 15(10): 2147-2151
20
"1 The reviewer's detailed comments are of great help to the improvement of my article，Let me better correct the details of the article ..."
[Read more]
"1 The reviewer's detailed comments are of great help to the improvement of my article，Let me better correct the details of the article to meet the requirements of your magazine. 2 The submission process is very smooth. 3 The communication with the editor's email was smooth, and the editor editor is patient and careful，replied to the email in time. Save time for both parties. "
[Collapse]
Zhou YM, Cao YH, Guo J, Cen LS. Potential prospects of Chinese medicine application in diabetic retinopathy. World J Diabetes 2024; 15(10): 2010-2014
16522 items Read more >>
1
"I am surprised that the prepublication review did not indicate that the paper was really a textbook-type exposition of Li-Fraumeni ..."
[Read more]
"I am surprised that the prepublication review did not indicate that the paper was really a textbook-type exposition of Li-Fraumeni syndrome. Connection with the patient is "many cancers" with no further explanation. The cardiac findings are surprising. I have never seen an ASD (2 here!) without a pulmonary ejection murmur or cardiac enlargement. Thrombi on a valve also generally causes some noise."
[Collapse]
Al-Haggar MS, Abdelmoneim ZA. Tricuspid mass-curious case of Li-Fraumeni syndrome: A letter to the editor. World J Clin Cases 2024; 12(33): 6644-6646
2
"1. Scintigraphy related studies such as gastric emptying scintigraphy, intestinal transit scintigraphy and gastrointestinal bleeding ..."
[Read more]
"1. Scintigraphy related studies such as gastric emptying scintigraphy, intestinal transit scintigraphy and gastrointestinal bleeding scintigraphy have been used for various purposes. The relevant details can be included.
2. Role of SPECT / PET, especially in neuroendocrine tumours identification and management can be outlined
3. Image enhanced endoscopic techniques have been shown to identify early neoplastic lesions with greater accuracy. "
[Collapse]
Gong EJ, Bang CS. Advancements and challenges in gastrointestinal imaging. World J Clin Cases 2024; 12(33): 6591-6594
3
"1. Were the biochemical parameters, especially blood sugar profile under control? What was the medication - oral / injectible ..."
[Read more]
"1. Were the biochemical parameters, especially blood sugar profile under control? What was the medication - oral / injectible Insulin?
2. Was the patient advised adequate rest with limb elevation to achieve resolution of edema and tissue fluid accumulation?
3. What is necrectomy? Does this refer to wound debridement? Did it involve devitalised tisue and infected debris removal? Was a conservative approach considered?"
[Collapse]
Dimova A, Boroš M, Dimov S, Konjevod J, Svetec M. Platelet-rich plasma treatment for chronic wounds: A case report and literature review. World J Clin Cases 2024; 12(33): 6635-6643
4
"1. Factors relating to operator (learning, adaptation), equipment (options, probes) and patient (anatomy, build) may further help ..."
[Read more]
"1. Factors relating to operator (learning, adaptation), equipment (options, probes) and patient (anatomy, build) may further help in better classification and identification of success / failure of Artificial Intelligence in Regional Anesthesia
2. Relevant illustrations can be useful
3. Overall, the layout of the manuscript with details of the models and the indepth review is appreciable"
[Collapse]
Swain BP, Nag DS, Anand R, Kumar H, Ganguly PK, Singh N. Current evidence on artificial intelligence in regional anesthesia. World J Clin Cases 2024; 12(33): 6613-6619
5
"Interesting article, a brief review of biomarkers in CCR.
1 Ethics: The manuscript complies the ethical standard.
2 Methods: ..."
[Read more]
"Interesting article, a brief review of biomarkers in CCR.
1 Ethics: The manuscript complies the ethical standard.
2 Methods: Narrative review with easy language and well summarized.
3 Results: Does not apply.
4 Figures and tables: Does not apply
5 Biostatistics: Does not apply.
6 References: Well referenced with useful bibliography.
Is a good article but in my opinion no deserve a prize."
[Collapse]
Tez M. Inflammatory and nutritional markers in colorectal cancer: Implications for prognosis and treatment. World J Clin Oncol 2024; 15(10): 1264-1268
6
"Great article, well written:
1 Ethics: The article comply ethics statement.
2 Methods: Narrative manuscript well conected and ..."
[Read more]
"Great article, well written:
1 Ethics: The article comply ethics statement.
2 Methods: Narrative manuscript well conected and easy to read.
3 Results: No results.
4 Figures and tables: Does not apply.
5 Biostatistics: Does not apply.
6 References: Well referenced.
7 Language: Correctly, clearly and concisely.
Great article, but in my opinion is not for an award."
[Collapse]
Dursun CU, Tugcu AO, Dogru GD. Gastric metastasis of small cell lung carcinoma: A rare but noteworthy entity to consider. World J Clin Oncol 2024; 15(10): 1379-1382
7
"This study made a significant contribution by identifying potential biomarkers for diabetic cardiomyopathy (DCM) and offers a novel ..."
[Read more]
"This study made a significant contribution by identifying potential biomarkers for diabetic cardiomyopathy (DCM) and offers a novel perspective on the immune-cell interactions involved in the disease's pathology. However, the study's reliance on animal models and the absence of direct human clinical data suggest that future research should focus on validating these findings in human populations. Additionally, further exploration of the molecular mechanisms behind Penk and Rbp7 in immune cell interactions could provide deeper insights into their therapeutic potential in DCM."
[Collapse]
Zheng ZQ, Cai DH, Song YF. Identification of immune feature genes and intercellular profiles in diabetic cardiomyopathy. World J Diabetes 2024; 15(10): 2093-2110
8
"This study investigated the protective effects of asiaticoside (AC) against diabetic nephropathy (DN) using in vitro and in vivo ..."
[Read more]
"This study investigated the protective effects of asiaticoside (AC) against diabetic nephropathy (DN) using in vitro and in vivo models. The research makes a valuable contribution by demonstrating that AC can ameliorate DN by reducing inflammation, oxidative stress, and fibrosis through activation of the NRF2/HO-1 pathway. The authors have effectively elucidated AC's protective mechanisms in DN. However, some limitations should be considered. The streptozotocin-induced diabetes model may not fully recapitulate the complex pathophysiology of human DN. While the study demonstrates AC's effects on various markers, it does not provide direct evidence of improved renal function. The translation of these findings to clinical applications remains an unresolved issue. Future research could explore the long-term effects of AC treatment, investigate its efficacy in more chronic DN models, and examine potential synergistic effects with standard DN treatments. Additionally, studies in human cell lines or clinical trials would be necessary to establish AC's therapeutic potential in DN patients."
[Collapse]
Zhuang LG, Zhang R, Jin GX, Pei XY, Wang Q, Ge XX. Asiaticoside improves diabetic nephropathy by reducing inflammation, oxidative stress, and fibrosis: An in vitro and in vivo study. World J Diabetes 2024; 15(10): 2111-2122
9
"This study investigated the role of cuproptosis in acute kidney injury (AKI) following cardiopulmonary bypass (CPB) in diabetic ..."
[Read more]
"This study investigated the role of cuproptosis in acute kidney injury (AKI) following cardiopulmonary bypass (CPB) in diabetic patients, utilizing both clinical samples and animal models. Key findings include elevated copper levels, metabolic disturbances, and cuproptosis-related protein changes in diabetic patients after CPB. Animal experiments revealed significant mitochondrial damage and reduced expression of iron-sulfur cluster proteins in diabetic rat kidneys following CPB. Limitations include a small sample size in animal experiments and a lack of long-term follow-up data. Future research could consider exploring the long-term implications of cuproptosis-induced AKI and potential therapeutic strategies targeting this mechanism to prevent CPB-AKI in diabetic patients."
[Collapse]
Deng XJ, Wang YN, Lv CB, Qiu ZZ, Zhu LX, Shi JH, Sana SRGL. Effect of cuproptosis on acute kidney injury after cardiopulmonary bypass in diabetic patients. World J Diabetes 2024; 15(10): 2123-2134
10
"This case report details the successful treatment of a 72-year-old male's chronic, non-healing leg wound using autologous platelet-rich ..."
[Read more]
"This case report details the successful treatment of a 72-year-old male's chronic, non-healing leg wound using autologous platelet-rich plasma (PRP). Despite multiple antibiotic regimens and standard wound care failing to heal the wound over seven months, three PRP applications resulted in complete epithelial layer restitution. The authors suggest PRP as a beneficial treatment option for chronic wounds, particularly after other methods have proven ineffective, although further research is needed to standardize PRP protocols and assess long-term effects. The case highlights PRP's potential to reduce healing time and improve patient quality of life. A well written manuscript which shows potential use of PRP in various spheres of medical science. "
[Collapse]
Dimova A, Boroš M, Dimov S, Konjevod J, Svetec M. Platelet-rich plasma treatment for chronic wounds: A case report and literature review. World J Clin Cases 2024; 12(33): 6635-6643
11
"This systematic review with network meta-regressions effectively analyzes the combination of GLP-1 receptor agonists and SGLT-2 ..."
[Read more]
"This systematic review with network meta-regressions effectively analyzes the combination of GLP-1 receptor agonists and SGLT-2 inhibitors for cardiovascular disease prevention in type 2 diabetes. The study employs a sophisticated network meta-regression approach to estimate combination treatment effects. The review suggests potential additional cardiovascular benefits from combining GLP-1 receptor agonists and SGLT-2 inhibitors, particularly in patients with prior myocardial infarction or heart failure. While the authors address the challenge of estimating combination treatment effects, some results remain inconclusive due to wide confidence intervals. The reliance on trial-level rather than individual patient data is also a limitation. Future research using individual patient data and definitive trials is recommended to validate these findings and provide more precise estimates across patient subgroups."
[Collapse]
Zhu JJ, Wilding JPH, Gu XS. Combining GLP-1 receptor agonists and SGLT-2 inhibitors for cardiovascular disease prevention in type 2 diabetes: A systematic review with multiple network meta-regressions. World J Diabetes 2024; 15(10): 2135-2146
12
"This study analyzed the relationship between various thyroid hormone sensitivity indices, such as TFQI, TSHI, and TT4RI, and ..."
[Read more]
"This study analyzed the relationship between various thyroid hormone sensitivity indices, such as TFQI, TSHI, and TT4RI, and dyslipidemia in patients with type 2 diabetes. It revealed that impaired thyroid hormone sensitivity is independently associated with elevated non-HDL-C levels. It emphasized the importance of considering thyroid hormone resistance in managing cardiovascular risk in diabetic patients. Despite these scientific strengths, there are some limitations. As a cross-sectional observational study, it cannot definitively establish a causal relationship between thyroid hormone sensitivity and non-HDL-C levels. The study's confinement to a single hospital in China may limit the generalizability of results to a broader population. The study effectively visualized key relationships, particularly using SHAP summary plots to rank the impact of thyroid-related variables on high non-HDL-C. The biostatistics were well-executed, and the logistic regression models provided clear associations. Future research should address these limitations by conducting longitudinal studies and expanding the study population to improve clinical applicability."
[Collapse]
Duan XY, Fu JL, Sun LN, Mu ZJ, Xiu SL. Association between sensitivity to thyroid hormones and non-high-density lipoprotein cholesterol levels in patients with type 2 diabetes mellitus. World J Diabetes 2024; 15(10): 2081-2092
13
"This study on delayed treatment of diabetic foot ulcers in type 2 diabetes patients provides valuable insights into risk factors and ..."
[Read more]
"This study on delayed treatment of diabetic foot ulcers in type 2 diabetes patients provides valuable insights into risk factors and predictive models. The results highlight important associations between factors like BMI, glucose levels, HbA1c, diabetic complications, and delayed medical care with diabetic foot occurrence. The combined predictive model showed good value with an AUC of 0.933. While the study is well-conducted and presented, some limitations exist. The retrospective design limits causal inferences, and the single-center nature may impact generalizability. More exploration of reasons behind medical delays could inform intervention strategies. Future prospective multicenter trials are necessary to validate the model further and extend its applicability to a broader population. Investigating patient education and healthcare system factors contributing to delayed care could provide a more comprehensive approach to this critical issue in diabetes management."
[Collapse]
Chen H, Xi Y. Delayed treatment of diabetic foot ulcer in patients with type 2 diabetes and its prediction model. World J Diabetes 2024; 15(10): 2070-2080
14
"This review on the cGAS-STING pathway effectively discusses its role in inflammation and metabolic disorders in diabetes, particularly ..."
[Read more]
"This review on the cGAS-STING pathway effectively discusses its role in inflammation and metabolic disorders in diabetes, particularly its therapeutic potential in complications like diabetic cardiomyopathy and nephropathy. While scientifically sound, the paper primarily relies on preclinical data, lacking clinical evidence to support the findings. The figures are clear, but complex interactions could benefit from better visualization. Future research should focus on validating these insights through clinical trials and exploring long-term safety. In summary, the study offers a strong foundation but requires clinical validation to fully realize the potential of cGAS-STING targeting in diabetes management."
[Collapse]
Fan MW, Tian JL, Chen T, Zhang C, Liu XR, Zhao ZJ, Zhang SH, Chen Y. Role of cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes pathway in diabetes and its complications. World J Diabetes 2024; 15(10): 2041-2057
15
"This study on Interleukin-35 (IL-35) provides important insights into its role in modulating immune responses in pre-diabetes and ..."
[Read more]
"This study on Interleukin-35 (IL-35) provides important insights into its role in modulating immune responses in pre-diabetes and chronic autoimmune type 1 diabetes. The study's strength lies in its thorough gene-disease analysis, but the lack of experimental validation highlights a key area for improvement. The authors propose future research through interdisciplinary collaboration and advanced methodologies, but long-term clinical studies remain crucial to understanding IL-35's therapeutic potential. Overall, the findings are an important first step but require further exploration for clinical relevance."
[Collapse]
Chakraborty R, Mukherjee AK, Bala A. Interleukin-35: A key player managing pre-diabetes and chronic inflammatory type 1 autoimmune diabetes. World J Diabetes 2024; 15(10): 2147-2151
16
"This letter summarizes research on gut microbiota (GM) in diabetes mellitus (DM), highlighting the potential role of GM dysbiosis ..."
[Read more]
"This letter summarizes research on gut microbiota (GM) in diabetes mellitus (DM), highlighting the potential role of GM dysbiosis in DM pathogenesis and the promising field of GM-targeted interventions. The authors address the complex GM-DM relationship, noting substantial evidence from animal studies while acknowledging limitations in human research. They emphasize the need for studies to clarify GM-DM causality and mechanisms to develop effective therapies. The editorial stresses the importance of considering interindividual GM heterogeneity when designing interventions, suggesting that personalized approaches may be necessary. The authors call for interdisciplinary collaboration and advanced technologies to develop precise, personalized therapeutic strategies while emphasizing the need for long-term studies to evaluate GM-targeted interventions in DM management."
[Collapse]
Wang J, Wei HJ, Mao RF, Chang X. Gut microbiota modulating therapy for diabetes mellitus should be individualized. World J Diabetes 2024; 15(10): 2152-2156
17
"This editorial effectively compares bariatric surgery and glucagon-like peptide-1 receptor agonist (GLP-1RA) therapy for managing ..."
[Read more]
"This editorial effectively compares bariatric surgery and glucagon-like peptide-1 receptor agonist (GLP-1RA) therapy for managing obesity-associated type 2 diabetes, highlighting their efficacy across different age groups. The authors successfully address the safety and effectiveness of both approaches in pre-teens, teenagers, and older individuals, while noting the limited data on newer GLP-1RAs in younger populations. They also discuss the paradoxical effects of GLP-1RAs on post-bariatric surgery hypoglycemia, potentially reducing its frequency and severity. However, challenges remain, including the need for long-term comparative studies between bariatric surgery and GLP-1RAs, concerns about bone mineral density loss and muscle mass reduction with GLP-1RA use in older individuals, and the high discontinuation rates of GLP-1RA therapy. The authors suggest further research to optimize the use of both treatments, particularly in addressing their long-term efficacy, safety, and potential for combination with other interventions, such as exercise, while emphasizing the growing role of GLP-1RAs as a non-invasive alternative to bariatric surgery in managing obesity and type 2 diabetes."
[Collapse]
Jalleh RJ, Jones KL, Islam MS, Cai L, Horowitz M. Surgical or medical treatment of obesity-associated type 2 diabetes-an increasing clinical conundrum. World J Diabetes 2024; 15(10): 2036-2040
18
"This editorial effectively summarizes recent advancements in immunotherapy for type 1 diabetes, highlighting antibody-based, ..."
[Read more]
"This editorial effectively summarizes recent advancements in immunotherapy for type 1 diabetes, highlighting antibody-based, antigen-based, and stem cell-based approaches while addressing key issues such as the mechanisms and potential of various therapies, particularly teplizumab. The authors clearly explain the limitations of current therapies, including inconsistent results and narrow treatment windows. However, several challenges remain unresolved, including the need for large-scale clinical trials, high treatment costs, and difficulties in identifying suitable candidates. To address these issues, the authors propose developing more widespread screening programs, conducting longer-term follow-up studies, and exploring combination therapies and personalized approaches."
[Collapse]
Ray S, Palui R. Immunotherapy in type 1 diabetes: Novel pathway to the future ahead. World J Diabetes 2024; 15(10): 2022-2035
19
"This editorial effectively summarizes the complex role of mitochondria in diabetes and the challenges of targeting them ..."
[Read more]
"This editorial effectively summarizes the complex role of mitochondria in diabetes and the challenges of targeting them therapeutically. The authors clearly explain why mitochondria-targeted antioxidants yield inconsistent results in glycemic control but show potential in mitigating diabetic complications. Unresolved issues include the lack of preclinical models that accurately mimic human diabetes, the scarcity of large-scale clinical trials, and the need for more efficient drug delivery methods. To address these challenges, the authors propose enhancing academia-industry collaborations, exploring alternative approaches like Elamipretide and mitochondrial transplantation, and utilizing computational methods to improve drug design."
[Collapse]
Cortés-Rojo C, Vargas-Vargas MA. Don´t give up on mitochondria as a target for the treatment of diabetes and its complications. World J Diabetes 2024; 15(10): 2015-2021
20
"This editorial effectively summarizes the potential of genipin, a traditional Chinese medicine extract, in treating diabetic ..."
[Read more]
"This editorial effectively summarizes the potential of genipin, a traditional Chinese medicine extract, in treating diabetic retinopathy (DR) through intraocular injection. The authors highlight the limitations of current DR treatments and present genipin as a promising alternative, demonstrating its ability to protect retinal cells from high glucose-induced damage via the CHGA/UCP2/GLUT1 signaling pathway. The editorial successfully contextualizes the use of traditional Chinese medicine in DR treatment, discussing various extracts and their mechanisms of action. However, challenges remain, including the need for more rigorous safety studies on intraocular injections of herbal medicines, standardization of quality control measures, and large-scale clinical trials to validate efficacy. "
[Collapse]
Zhou YM, Cao YH, Guo J, Cen LS. Potential prospects of Chinese medicine application in diabetic retinopathy. World J Diabetes 2024; 15(10): 2010-2014
14859 items Read more >>
Peer-Reviewers and Manuscript Statistics
- Editorial board members
- 3029
- Peer-reviewers
- 72146
- Manuscripts received today
- 9
- Manuscript reviews today
- 21
- Unhandled manuscripts today
- 132
- Active peer-reviewers today
- 553
- Reviewer acceptance today
- 11
- Reviewer refusals today
- 34
- Total accepted manuscripts
- 33235
- Total rejected manuscripts
- 38354
- Total peer-reviewers
- 3362279
- Total submissions
- 31485
1
2025-03-20 | Browse: 286 | Download: 48
2
3
2025-03-20 | Browse: 569 | Download: 64
4
2025-03-20 | Browse: 476 | Download: 52
5
6
2025-03-20 | Browse: 498 | Download: 73
7
8
2025-03-20 | Browse: 339 | Download: 81
9
2025-03-20 | Browse: 356 | Download: 76
10
11
12
13
14
15
2024-12-20 | Browse: 1816 | Download: 150
16
2024-12-20 | Browse: 1634 | Download: 143
17
2024-12-20 | Browse: 1785 | Download: 131
18
2024-12-20 | Browse: 2211 | Download: 164
19
20
2024-12-20 | Browse: 1515 | Download: 146
55984 items Read more >>
1
2
3
2024-09-29 | Browse: 63 | Download: 73
4
5
2024-09-29 | Browse: 70 | Download: 55
6
2024-09-29 | Browse: 66 | Download: 66
7
2024-09-29 | Browse: 65 | Download: 63
8
9
10
2024-09-29 | Browse: 64 | Download: 42
11
12
13
14
15
2024-09-29 | Browse: 70 | Download: 64
16
17
2024-09-28 | Browse: 85 | Download: 98
18
2024-09-28 | Browse: 67 | Download: 87
19
20
8704 items Read more >>
63923 items Read more >>
1
"Commentary: Predictors of survival in autoimmune liver disease overlap syndromes Jian-Guo Zhang,Biao Wen Jian-Guo Zhang,Biao ..."
[Read more]
"Commentary: Predictors of survival in autoimmune liver disease overlap syndromes Jian-Guo Zhang,Biao Wen Jian-Guo Zhang,Biao Wen,Department of Gastroenterology, The First Affiliated Hospital of Chengdu Medical College, Chengdu 610000, Sichuan Province, China Author contributions:Jian-Guo Zhang wrote the original draft; Biao Wen contributed to conceptualization, writing, reviewing and editing; Jian-Guo Zhang and Biao Wen participated in drafting the manuscript; and all authors have read and approved the final version of the manuscript. ORCID number：0000-0001-5226-5981 Corresponding author:Biao Wen,MD, PhD,Assistant Professor,Department of Gastroenterology, The First Affiliated Hospital of Chengdu Medical College,No. 312, Middle Section of Baoguang Avenue, Xindu District, Chengdu 610000, Sichuan Province, China. 820695761@qq.com We perused the article authored by Jayabalan et al[1]with considerable interest and extend our congratulations to the authors for their commendable endeavor. The authors have reported a prospective investigation into the predictors of survival in patients with autoimmune liver disease overlap syndromes (AILDOS)[1]. The study's conclusion suggests that the LOS holds potential as a predictive tool for liver-related mortality in individuals with autoimmune hepatitis and primary biliary cholangitis overlap (AIH-PBC)[1]. However, several aspects of this study merit further scrutiny and discussion. Firstly, a critical exclusion criterion for the study was the prior performance of a liver transplant prior to enrollment[1]. Upon consideration, we postulated the possibility that a portion of the enrolled patients might harbor coexisting liver pathology stemming from disparate causes (including, but not limited to, alcoholic liver disease or viral hepatitis), which could introduce bias and complicate the interpretation of our results. Therefore, we advised the authors to implement rigorous exclusion criteria for such patients to uphold the accuracy and reliability of our findings. Secondly, the diagnoses of autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC), and primary sclerosing cholangitis (PSC) were established in accordance with the criteria stipulated by the International Autoimmune Hepatitis Group, the European Association for the Study of the Liver Clinical Practice Guidelines, and the American College of Gastroenterology Clinical Guidelines, respectively[1-4]. It is noteworthy that these diagnostic criteria originate from disparate geographical regions, and the progression of research concerning each disease varies across these regions. Consequently, such variability may potentially impact the precision of the study's findings. In light of this, we propose that the authors consider adopting diagnostic criteria from a uniform geographical region. Therefore, we recommend the uniform application of diagnostic guidelines or consensus recommendations established by reputable institutions in the United States for the purposes of disease ascertainment. Such standardization is poised to substantially elevate the reliability and validity of the research findings, thereby reinforcing the scientific rigor and credibility of the conducted studies.[4-6]. Thirdly, the authors confined their analysis solely to the occurrence or absence of liver-related mortality, while neglecting to account for the medical interventions undergone by the patients during the follow-up period[1]. It is imperative to elucidate the potential impact of these interventions on the study's findings. A comprehensive assessment of the medical interventions received by the patients is crucial for ensuring the accuracy and robustness of the study's conclusions. Ultimately, as highlighted by the authors, the primary limitation of this study is the relatively modest sample size[1]. Consequently, it is imperative that future research endeavors incorporate larger sample populations and adopt a multicenter design to validate the findings of the present study and further elucidate the pertinence to patients with AIH-PSC. Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported. REFERENCES 1 Jayabalan D, Huang Y, Calzadilla-Bertot L, Janjua M, de Boer B, Joseph J, Cheng W, Hazeldine S, Smith BW, MacQuillan GC, Wallace MC, Garas G, Adams LA, Jeffrey GP. Predictors of survival in autoimmune liver disease overlap syndromes. World J Hepatol 2024; 16: 1269-1277. [PMID:39351512 DOI: 10.4254/wjh.v16.i9.1269] 2 European Association for the Study of the Liver. EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis. J Hepatol 2017; 67: 145-172. [PMID: 28427765 DOI: 10.1016/j.jhep.2017.03.022] 3 Czaja AJ. Diagnosis and Management of Autoimmune Hepatitis: Current Status and Future Directions. Gut Liver 2016; 10: 177-203. [PMID:26934884 DOI: 10.5009/gnl15352] 4 Lindor KD, Kowdley KV, Harrison ME. ACG Clinical Guideline: Primary Sclerosing Cholangitis. Am J Gastroenterol 2015; 110: 646-659, 660. [PMID: 25869391 DOI: 10.1038/ajg.2015.112] 5 Mack CL, Adams D, Assis DN, Kerkar N, Manns MP, Mayo MJ, Vierling JM, Alsawas M, Murad MH, Czaja AJ. Diagnosis and Management of Autoimmune Hepatitis in Adults and Children: 2019 Practice Guidance and Guidelines From the American Association for the Study of Liver Diseases. Hepatology 2020; 72: 671-722. [PMID: 31863477 DOI: 10.1002/hep.31065] 6 Lindor KD, Bowlus CL, Boyer J, Levy C, Mayo M. Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases. Hepatology 2019; 69: 394-419. [PMID:30070375 DOI: 10.1002/hep.30145] "
[Collapse]
Jayabalan D, Huang Y, Calzadilla-Bertot L, Janjua M, de Boer B, Joseph J, Cheng W, Hazeldine S, Smith BW, MacQuillan GC, Wallace MC, Garas G, Adams LA, Jeffrey GP. Predictors of survival in autoimmune liver disease overlap syndromes. World J Hepatol 2024; 16(9): 1269-1277
2
"Comment on “Mesenchymal stem cells in wound healing: A bibliometric analysis as a powerful research tool” Shuang Wu, Hong Cai* ..."
[Read more]
"Comment on “Mesenchymal stem cells in wound healing: A bibliometric analysis as a powerful research tool” Shuang Wu, Hong Cai* Corresponding author: Hong Cai, Department of Dermatology, Air Force Medical Center, PLA, Beijing, 100142, P. R. China. ch1031@163.com Affiliation: Department of Dermatology, Department of Dermatology, Air Force Medical Center, PLA. No.30 of Fucheng Road. Beijing 100142, China. Key Words: Bibliometric analysis; Mesenchymal stem cells; Wound healing; To the Editor: We read the editorial by Vera et al [1]with great interest. In this editorial, the author conducted a keyword comparison and analysis of basic research published in BPG from 2023 to 2024, utilizing the bibliometric analysis approach of Shi et al[2]. This emphasizes the effectiveness of bibliometric analysis as a research tool. Additionally, the author examined several other articles on BPG, excluding WJSC, that were not included in Shi et al.'s bibliometric analysis. The findings indicate that although the application of bibliometric analysis in basic research remains limited, it can help identify key research directions and challenges in the field, advance the application of MSCs in the treatment of chronic wounds, and facilitate comprehensive analysis of related literature to better understand the current state of research and future development potential. First, the author conducted a keyword analysis of basic research on diabetic foot published in BPG, utilizing the bibliometric analysis by Shi et al. to highlight the value of bibliometric analysis in this field, which can provide clear directions for research hotspots. However, while Shi et al. used the Web of Science Core Collection database, the author of this article relied solely on the database affiliated with BPG for keyword comparisons. This discrepancy might introduce potential biases in the analysis results due to differences in research directions and acceptance criteria between journals[3,4]. Second, the author also pointed out limitations in Shi et al.'s bibliometric analysis: the analysis primarily focused on journals related to diabetic foot, while literature from other relevant fields was excluded from the search. This implies that some articles pertaining to stem cell therapy for diabetic foot may not have been incorporated, underscoring the necessity of expanding the search scope in future bibliometric analyses. Third, the author specifically analyzed literature on stem cell therapy for diabetic foot published in BPG during 2023-2024, while Shi et al.'s bibliometric analysis covered related literature from 2000 to 2023, thereby including a broader time span and a more extensive range of keywords. As basic research evolves, there may be past hotspot keywords that are now rarely used, or new research hotspots published in BPG that were not included in Shi et al.'s bibliometric analysis[5]. In summary, this is an editorial that employs bibliometric analysis to conduct a keyword analysis of relevant papers published in BPG from 2023 to 2024, elucidating the role of bibliometric analysis in basic research. If the analysis were to consider the acceptance criteria of different journals and the issue of timeliness more extensively, the conclusions could potentially be more compelling. References 1 Voinova VV, Vasina DV, Bonartsev AP. Mesenchymal stem cells in wound healing: A bibliometric analysis as a powerful research tool. World J Stem Cells 2024; 16: 827–831. [PMID: 39351262 DOI: 10.4252/wjsc.v16.i9.827] 2 Shi H-S, Yuan X, Wu F-F, Li X-Y, Fan W-J, Yang X, Hu X-M, Liu G-B. Research progress and challenges in stem cell therapy for diabetic foot: Bibliometric analysis and perspectives. World J Stem Cells 2024; 16: 33–53. [PMID: 38292441 DOI: 10.4252/wjsc.v16.i1.33] 3 Frank E. Authors’ Criteria for Selecting Journals. JAMA 1994; 272: 163–164. [DOI: 10.1001/jama.1994.03520020089026] 4 Garfield E. The History and Meaning of the Journal Impact Factor. JAMA 2006; 295: 90–93. [DOI: 10.1001/jama.295.1.90] 5 Tversky A, Kahneman D. Judgment under Uncertainty: Heuristics and Biases. Science 1974; 185: 1124–1131. [DOI: 10.1126/science.185.4157.1124] "
[Collapse]
Voinova VV, Vasina DV, Bonartsev AP. Mesenchymal stem cells in wound healing: A bibliometric analysis as a powerful research tool. World J Stem Cells 2024; 16(9): 827-831
3
"The article by Shen et al. offers important insights into the need for better screening practices for primary nasal tuberculosis (TB) ..."
[Read more]
"The article by Shen et al. offers important insights into the need for better screening practices for primary nasal tuberculosis (TB) in patients receiving tumor necrosis factor inhibitor (TNFi) therapy. The rarity of primary nasal TB, due to the nasal mucosa's natural defenses, along with the identified risk factors like diabetes, minimally invasive nasal surgery, and HIV, is well highlighted. We completely agree with the authors about the importance of early detection, especially in high-risk individuals. Their suggestion to increase screening frequency using the Interferon Gamma Release Assay (IGRA) makes sense. However, it’s also worth considering how practical this approach is in areas with lower TB prevalence. In regions with fewer resources, a more targeted strategy based on local TB rates and individual patient risk might be more appropriate. Another point to consider is how clinicians can best decide on the timing of these screenings. While IGRA testing is key, decisions on how often to test should also factor in a patient’s specific history, immune status, and any symptoms they might be experiencing. A one-size-fits-all approach may not work, so a more flexible screening schedule, tailored to both the patient’s needs and the region’s TB prevalence, could be even more effective. We look forward to further research in this area which will help shape future guidelines for managing TB risk in this patient group. "
[Collapse]
Shen DX, Wang YW, Lin ZM, Jin D, Ying ZH, Li C. Early screening to identify and diagnose primary nasal tuberculosis in patients with tumor necrosis factor inhibitors. World J Clin Cases 2024; 12(33): 6604-6607
4
"First, I would like to congratulate the authors for their excellent work that reports precisely the role of ultrasonography as the ..."
[Read more]
"First, I would like to congratulate the authors for their excellent work that reports precisely the role of ultrasonography as the first step in diagnosing liver echinococcus cyst. The paper is comprehensive and well-written, accompanied by many impressive imaging figures. Echinococcosis or hydatid disease is caused mainly by the dog tapeworm Echinococcus granulosus and occasionally by the fox tapeworm Echinococcus multilocularis (alveolaris). Infection by the former exhibits a rather chronic, benign course. Infection by the latter, seen in north and central Europe, Switzerland, Alaska, Canada, Russia, Japan, and China, resembles carcinoma and without treatment is ultimately fatal; there have been reports mistaking it for hepatic carcinoma. The hydatid disease predominantly affects the liver, and surgical management, despite its difficulties and high recurrence rates, is considered the cornerstone of treatment. The incidence of liver echinococcal cyst has considerably reduced across the world owing to concerted public health hygiene and sanitary measures to disrupt the parasite cycle between the main host (dog,wolf, fox) and the intermediate host (human, sheep, cow, pig), but it remains endemic in some areas.. Diagnosis is established by current imaging techniques (US, CT, MRI-MRCP), aided by serum serology tests for antibodies against hydatid antigens. Specific anti-echinococcal antibodies (IgG, IgM), detected by ELISA (with a sensitivity of 95–97%) is the most widely used serologic test in everyday practice. Modern MRI depicts accurately the details of a hepatic echinococcal cyst as well as the communication with the biliary tree. MRCP showing dilatation of the biliary tract and echinococcal material in it may be valuable. Surgery is the main treatment modality in the management of liver echinococcosis caused by echinococcus granulosus, especially in large solitary cysts. It includes the most demanding radical procedures (total pericystectomy or hepatectomy) and the more conservative procedures (cyst evacuation, partial cystectomy, and drainage or omentoplasty). Complete removal of the cyst ensures permanent cure and should be the treatment of first-choice. In contrast, liver echinococcosis caused by echinococcus multilocularis (alveolaris) is not usually amenable to surgical treatment, except in drug therapy by Albendazole. It is used at a dose of 10 mg/kg/day. One tablet of 400 mg twice daily is the usual therapeutic scheme. A cycle of 28 days is recommended, followed by a washout period of 14 days, and repetition again. "
[Collapse]
Tao Y, Wang YF, Wang J, Long S, Seyler BC, Zhong XF, Lu Q. Pictorial review of hepatic echinococcosis: Ultrasound imaging and differential diagnosis. World J Gastroenterol 2024; 30(37): 4115-4131
5
"This retrospective study provide a machine learning method using nomogram to present medical imaging features associated with clinical ..."
[Read more]
"This retrospective study provide a machine learning method using nomogram to present medical imaging features associated with clinical factors via univariate and multivariate analysis in patients with colon cancer. Maybe the results of CT imaging with 12 characteristics as author stated is interesting for readers in clinic diagnosis as well as these representative images can be shared by your database online. "
[Collapse]
Hu ZX, Li Y, Yang X, Li YX, He YY, Niu XH, Nie TT, Guo XF, Yuan ZL. Constructing a nomogram to predict overall survival of colon cancer based on computed tomography characteristics and clinicopathological factors. World J Gastrointest Oncol 2024; 16(10): 4104-4114
6
"This article has explained the effects of mesenchymal stem cells and their derivatives in the non-alcoholic fatty liver disease and ..."
[Read more]
"This article has explained the effects of mesenchymal stem cells and their derivatives in the non-alcoholic fatty liver disease and alcohol-associated liver disease using mouse models. Maybe it is meaningful to indicate the application of mesenchymal stem cells in fatty liver in the future. Hope that interaction between mesenchymal stem cells and human hepatic cell lines can be investigated to explore this effective role for further use in the clinic. "
[Collapse]
Gao FQ, Zhu JQ, Feng XD. Innovative mesenchymal stem cell treatments for fatty liver disease. World J Stem Cells 2024; 16(9): 846-853
7
"Through this meta-analysis, better guidance has been provided for the treatment of tenosynovitis. USG-guided PRP with percutaneous ..."
[Read more]
"Through this meta-analysis, better guidance has been provided for the treatment of tenosynovitis. USG-guided PRP with percutaneous needle tenotomy gives better outcome in DQT. which provides better pain management and stable improvement in functional outcomes in the long term. Ultrasonography-guided PRP with percutaneous needle tenotomy gives a better outcome. There are minimal side effects associated with PPR injection. "
[Collapse]
Hidajat NN, Magetsari RMSN, Steven G, Budiman J, Prasetiyo GT. Platelet-rich plasma for de Quervain’s tenosynovitis: A systematic review and meta-analysis. World J Orthop 2024; 15(9): 858-869
8
"1. The case in this article needs to be clarified whether thought reaches delusional and its duration. If there is delusion, the ..."
[Read more]
"1. The case in this article needs to be clarified whether thought reaches delusional and its duration. If there is delusion, the diagnosis also needs to differentiate with delusional disorder. Another name is Ekbom syndrome, in which comprises of visual hallucinations and delusional parasitosis. Delusional parasitosis, which is characterized by a fixed and persistent belief of having a pathogenic infection despite objective evidence to the contrary. 2. The authors described the diagnosis of early dementia. However, the article did not mention the clinical course and symptoms of typical dementia in this patient, such as the patient's memory complaints, cognitive function deterioration, instrumental and basic activities of daily livings, and executive functions. The results of cognitive function assessment should be provided. 3. The case history mentioned that the patient had gait problems. The reader may wonder what the patient's neurological examination, especially the evaluation of the limbs and gait. A type of dementia called Lewy body dementia (DLB), and its core symptoms contain parkinsonism. DLB is also considered to be likely to have vivid visual hallucinations. 4. Authors can discuss the pathophysiology of psychotic symptoms in dementia and late life and review associated reports on the use of antipsychotics in such clinical situation. 5. If the patient meets the diagnosis of early dementia, the use of AchEI can be considered and discussed. Compared with antipsychotics, the advantage of using AchEI to treat psychiatric symptoms in dementia patients is that it does not affect cognitive function and has fewer extrapyramidal side effects. 6. Thanks for the author's paper. "
[Collapse]
Xu T, Mei X, Zhao Z, Liu YH, Zheng CY. Effectiveness of anti-psychiatric treatment on visual and haptic perceptual disorder for a patient with Alzheimer’s disease: A case report. World J Psychiatry 2024; 14(9): 1404-1410
9
"In this manuscript, the method of network pharmacology was used to explore the specific mechanism of Xiaojianzhong decoction treating ..."
[Read more]
"In this manuscript, the method of network pharmacology was used to explore the specific mechanism of Xiaojianzhong decoction treating gastric cancer, and the drug target network and gastric cancer differential genes were creatively used to analyze the potential therapeutic target, providing a new possibility for the treatment of gastric cancer. However, a fly in the ointment is that only GSE118916 is used for the differentially expressed gene related to gastric cancer, which makes its application value relatively insufficient. It should be understood that cancer is a complex disease related to multiple genes and multiple targets, and the use of multiple GEO chips to screen common pathogenic genes will make the study more universal. Using a single chip amplifies potential disease-causing genes and reduces the confidence of drug targets. "
[Collapse]
Chen GQ, Nan Y, Ning N, Huang SC, Bai YT, Zhou ZY, Qian G, Li WQ, Yuan L. Network pharmacology study and in vitro experimental validation of Xiaojianzhong decoction against gastric cancer. World J Gastrointest Oncol 2024; 16(9): 3932-3954
10
"The authors' proposed study aims to investigate the association between nutritional and inflammatory markers and the prognosis of ..."
[Read more]
"The authors' proposed study aims to investigate the association between nutritional and inflammatory markers and the prognosis of patients with CRC-PM. The article argues for the predictive role of NLR with respect to patients' OS, based on blood sampling performed one week before surgery regardless of the treatment the patient receives. It also constructs a nomogram on NLR, Hb and PCI (dividing patients into only two groups PCI > or 15 also, some studies consider a PCI>20 to be outside the chances of benefiting from any treatment), achievement of optimal surgical cytoreduction (CC0-CC1), type of peri-operative chemotherapy received by the patient, and tumor biology. the role played by HIPEC (and the various application protocols) is a matter of debate. The population on which NRL is tested and then the nomogram constructed is heterogeneous in both staging and treatment received. Characteristics of pre-surgical extent of disease are not known. Any chemotherapy treatments received by patients are not known. The authors pool patients who received only palliative treatments and those who received radical therapy into the same population. In summary, despite a large number of papers in the literature advocating the importance of careful evaluation/selection of patients with CRC-PM and the impact of treatments on patients' OS the authors support the selection role of a single inflammatory marker and base the construction of a nomogram on this. There is a risk of providing non-expert clinicians with an inadequate assessment tool that could lead to incorrect treatment choices. "
[Collapse]
Wu ZJ, Lan B, Luo J, Ameti A, Wang H, Hu QY. Impact of preoperative inflammatory and nutritional markers on the prognosis of patients with peritoneal metastasis of colorectal cancer. World J Gastrointest Oncol 2024; 16(9): 3865-3874
11
"This study explores the potential of resveratrol, a natural polyphenol, in targeting pancreatic cancer by depleting senescent ..."
[Read more]
"This study explores the potential of resveratrol, a natural polyphenol, in targeting pancreatic cancer by depleting senescent tumor-associated fibroblasts (TAFs). Tumor-associated fibroblasts play a key role in the tumor microenvironment, promoting cancer cell proliferation and metastasis. By depleting senescent TAFs, resveratrol disrupts this supportive environment, leading to inhibited cancer growth and spread. The findings suggest that resveratrol could be an effective therapeutic strategy for pancreatic cancer, especially in limiting metastasis. This study highlights the importance of targeting the tumor microenvironment and opens the door to potential combination therapies involving resveratrol in cancer treatment. The limitations of this study include the need for further validation in clinical settings, as the effects of resveratrol were primarily observed in preclinical models, which may not fully replicate human pancreatic cancer biology. The dosage and bioavailability of resveratrol in humans could also differ, potentially limiting its therapeutic efficacy. Additionally, the study focuses on depleting senescent tumor-associated fibroblasts (TAFs) but does not fully explore the long-term consequences of this depletion on the tumor microenvironment or potential side effects. More comprehensive studies are required to determine resveratrol's safety and effectiveness as a standalone or combination therapy. "
[Collapse]
Jiang H, Wang GT, Wang Z, Ma QY, Ma ZH. Resveratrol inhibits pancreatic cancer proliferation and metastasis by depleting senescent tumor-associated fibroblasts. World J Gastrointest Oncol 2024; 16(9): 3980-3993
12
"The subject with autologous conditioned serum (ACS) as a therapeutic agent for spine pathology is very interesting and the outcomes ..."
[Read more]
"The subject with autologous conditioned serum (ACS) as a therapeutic agent for spine pathology is very interesting and the outcomes from meta-analysis was great. Actually, the ACS method has not been widely used so far, so the kind of analysis could make it the feasibility and safety for spreading its use. However, the article has some minor limitations for the general use. Most of all, the articles used at the meta-analysis were made from duplicated institutes (just 3 different hospitals) and in the meta-analysis some statistical results were lacking, so it is hard to believe that the outcomes can be generalized. Nevertheless, the study has a strong point that only a few article have handled the ACS for confirming clinical effectiveness for spinal disease. Thus, the article can be a cornerstone of ACS use for spine pathology, and further studies regarding the ACS are necessary to greater define the effectiveness and safety. "
[Collapse]
Rajkovic CJ, Merckling ML, Lee AW, Subah G, Malhotra A, Thomas ZD, Zeller SL, Wainwright JV, Kinon MD. Conservative management of spinal pathology with autologous conditioned serum: A systematic review of the literature. World J Orthop 2024; 15(9): 870-881
13
"We recognize the innovation and practical value of this article, which comprehensively summarizes the bone marrow mesenchymal stem ..."
[Read more]
"We recognize the innovation and practical value of this article, which comprehensively summarizes the bone marrow mesenchymal stem cells (BMSCs) biological properties, outlines the role and mechanism of BMSCs in alleviating PNI, and suggests that transplantation of BMSCs for the treatment of PNI has a broad prospect. We are very grateful to the authors for their commitment to the study of BMSCs for alleviating nerve injury, which will help to elucidate the biological mechanisms related to the amelioration of PNI by BMSCs, and provide a solid foundation for basic and clinical research. 1.The article is a bit thin in terms of pictures and tables, and it would be more beautiful if we could add a table and a picture in moderation. Because pictures can illustrate specific things at a glance and are more vivid than words. 2.Bioengineering and nanotechnology have been hot directions for MSCs in recent years, with broad application potentials and a crucial role in PNI recovery, but the study has been depicted somewhat, but not in great depth. 3.The clinical trials section is poorly discussed and lacks in-depth exploration of their progress and potential. If there are few, then at least clinical trials for neurologically related diseases or other similar diseases should be added to elucidate the current progress of clinical research on MSCs, such as routes of administration, dosage of administration, and safety. 4.The biology of BMSCs (in terms of structure, origin, homing, targeting, etc.) is poorly characterized, and these are critical for the cells to perform their physiological functions for the treatment of PNI. 5.The multidirectional differentiation characteristics, immunomodulatory effects and simplicity of in vitro isolation, culture and expansion of BMSCs have laid the foundation for their clinical application. However, in the process of specific clinical application, the safety and effectiveness of BMSCs must be affirmed, based on which attention should be paid to the standardization of cell culture, the survival of implanted cells, and the inherent differentiation characteristics of the cells as well as immune rejection, etc.; the prospects and challenges of the clinical trials in this study have not yet been elucidated in depth. 6.In addition, the bibliography of the article is somewhat outdated, and it would have been better if more than 70 per cent of the bibliography had been from the last three years, so that at least the currency of the article could have been ensured. "
[Collapse]
Zou XF, Zhang BZ, Qian WW, Cheng FM. Bone marrow mesenchymal stem cells in treatment of peripheral nerve injury. World J Stem Cells 2024; 16(8): 799-810
14
"The most significant contribution of this editorial is the clear establishment of sarcopenia and myosteatosis as independent ..."
[Read more]
"The most significant contribution of this editorial is the clear establishment of sarcopenia and myosteatosis as independent prognostic factors that significantly impact the outcomes of gastric cancer patients treated with immune checkpoint inhibitors (ICIs). While the authors reference studies that confirm these associations, the editorial falls short in providing sufficient details on the mechanisms and implications of sarcopenia and myosteatosis. Expanding on these aspects would enhance understanding and underscore the importance of addressing these conditions in clinical practice. "
[Collapse]
Yang YN, Wang LS, Dang YQ, Ji G. Evaluating the efficacy of immunotherapy in gastric cancer: Insights from immune checkpoint inhibitors. World J Gastroenterol 2024; 30(32): 3726-3729
15
"In their meta-analysis, the authors demonstrated that the clinical outcomes except mortality consistently showed a worsening trend ..."
[Read more]
"In their meta-analysis, the authors demonstrated that the clinical outcomes except mortality consistently showed a worsening trend in patients with NAFLD and concomitant COVID-19, although further research in conducting prospective longitudinal studies is essential for a more powerful conclusion. The results are not unexpected given the numerous sources for COVID-19 detrimental development in patients with chronic liver and other concomitant diseases. As a slight limitation I consider the results section in the abstract, it could be more efficiently presented. "
[Collapse]
Moeed A, Larik MO, Fahim MAA, Rahman HAU, Najmi L, Changez MIK, Javed MM, Hasibuzzaman MA. Impact of non-alcoholic fatty liver disease on coronavirus disease 2019: A systematic review. World J Hepatol 2024; 16(8): 1185-1198
16
"Dear Editor, We would like to submit the enclosed manuscript entitled “Microvesicles derived from mesenchymal stem cells: a promising ..."
[Read more]
"Dear Editor, We would like to submit the enclosed manuscript entitled “Microvesicles derived from mesenchymal stem cells: a promising therapeutic strategy for acute respiratory distress syndrome-related pulmonary fibrosis?”, which we wish to be considered for publication in World Journal of Stem cells. This is an invited manuscript and my ID is 07415442. It is submitted to be considered for publication as a EDITORIAL in your journal. This paper is new. Neither the entire paper nor any part of its content has been published or has been accepted elsewhere. It is not being submitted to any other journal. Pulmonary fibrosis is a significant predictor of poor outcomes in patients with acute respiratory distress syndrome (ARDS). Currently, there is a lack of effective therapeutic options for pulmonary fibrosis in clinical practice. Therefore, there is an urgent need to identify safe and effective treatment strategies. This article provides a concise overview of the role of mesenchymal stem cells (MSCs), microvesicles (MVs), and hepatocyte growth factor (HGF) in pulmonary fibrosis, with a focus on their implications in both basic research and clinical practice. Furthermore, it examines the potential applications and challenges associated with the use of MSC-MVs as a novel therapeutic approach. Because your journal welcomes manuscripts in stem cells, we feel that this work is of general interest and is suitable for publication in World Journal of Stem cells. Thank you very much for considering our manuscript for potential publication. We are looking forward to hearing from you soon. "
[Collapse]
Chen QH, Zhang Y, Gu X, Yang PL, Yuan J, Yu LN, Chen JM. Microvesicles derived from mesenchymal stem cells inhibit acute respiratory distress syndrome-related pulmonary fibrosis in mouse partly through hepatocyte growth factor. World J Stem Cells 2024; 16(8): 811-823
17
"The paper offers valuable insights into lymphocyte phenotypes in patients with liver cirrhosis, contributing significantly to our ..."
[Read more]
"The paper offers valuable insights into lymphocyte phenotypes in patients with liver cirrhosis, contributing significantly to our understanding of immune alterations in this condition. However, a mild critique lies in the abstract, which, unfortunately, does not adequately reflect the depth and specificity of the results presented. This omission may inadvertently limit the paper's reach and impact by not fully engaging potential readers. Despite this, the study is commendable for its rigorous and well-detailed methodology, which ensures the validity of its findings. The results are not only statistically significant but also hold considerable practical relevance for clinical applications and further research in the field. "
[Collapse]
Li Y, Quan X, Tai Y, Wu YT, Wei B, Wu H. Causal association between 731 immunocyte phenotypes and liver cirrhosis: A bidirectional two-sample mendelian randomization analysis. World J Hepatol 2024; 16(8): 1156-1166
18
"The title of "Retrospective study evaluating association of colorectal tumors and hepatitis C virus" paper seems meaningful in the ..."
[Read more]
"The title of "Retrospective study evaluating association of colorectal tumors and hepatitis C virus" paper seems meaningful in the clinical analysis of both outcomes of HCV and pathogenic factors of colorectal tumors. Maybe author can discuss the effects of viral pathogens such as HBV, HIV besides HCV in the development of colorectal tumors. "
[Collapse]
Gogtay M, Yadukumar L, Singh Y, Suresh MG, Soni A, Yekula A, Bullappa A, Abraham GM. Retrospective study evaluating association of colorectal tumors and hepatitis C virus. World J Virol 2024; 13(3): 92647
19
"There are some methodological concerns that we would highlight. In their exclusion criteria, we note that the authors excluded ..."
[Read more]
"There are some methodological concerns that we would highlight. In their exclusion criteria, we note that the authors excluded patients with serious underlying disease, The extent of severity of comorbidities to warrant exclusion was not defined. Furthermore, patients with immediate postoperative complications were also excluded from final analysis. These exclusions may introduce an element of selection bias into the analysis, as only the fittest patients who had an uneventful postoperative course were included in the final analysis. It is also concerning that there is no mention of provision of neoadjuvant or perioperative systemic therapy for these gastric cancer patients, as is the standard of care in locally advanced gastric cancer throughout the world. It would have been interesting to know if there was an association between receiving perioperative chemotherapy, such as FLOT, and survival outcomes, or with the presence of vascular tumour thrombosis. There would have been a subset of patients with early gastric cancer that would have had upfront surgery as well, which would have opened the door to a subgroup analysis of patients that received neoadjuvant therapy vs. those that didn’t. The completeness of this study would have benefited from reporting mean or median follow up durations, as well completeness of follow up. There was no discussion regarding recurrence or disease-free intervals. Ultimately, this study adds to an already sizeable pool of knowledge that suggests that the presence of microvascular invasion in gastric cancer is associated with poorer survival outcomes. "
[Collapse]
Chen GY, Ren P, Gao Z, Yang HM, Jiao Y. Analysis of vascular thrombus and clinicopathological factors in prognosis of gastric cancer: A retrospective cohort study. World J Gastrointest Oncol 2024; 16(8): 3436-3444
20
Fernandez CJ, Shetty S, Pappachan JM. Diabetic cardiomyopathy: Emerging therapeutic options. World J Diabetes 2024; 15(8): 1677-1682
855 items Read more >>
- ALL AUTHOR RESOURCES
- Appeals and Complaints
- Article Processing Charge
- Common Usage of Quantities and Units
- Copyright License Agreement
- Create an Account
- Criteria for Authorship
- Ethics Committee of Baishideng
- Guidelines for Authors
- Guidelines for Manuscript Type and Related Ethics Documents
- Guidelines on Methods of Post-Publication Debate
- Journals
- Language Editing Process for Manuscripts Submitted by Non-Native Speakers of English
- Open-Access
- Policies on Handle Allegations from Whistleblowers
- Publication Misconduct
- Quality of Publications
- Steps for Submitting Manuscripts
- Submit a Manuscript
- ALL PEER-REVIEWER RESOURCES
- Manuscript Decision
- Peer-Review Process
- Peer-Reviewer Tracking for Manuscripts
- Reviewer Acknowledgment
- REFERENCE CITATION ANALYSIS
- Find a Category
- Find a Journal
- Find a Scholar
- Find an Academic Assistant
- Find an Article
- Find an Article PDF
- Subscribe
- Today's Articles
© 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
California Corporate Number: 3537345