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Contents Volume 27 Issue 43 November 21, 2021

Frontier

Antimicrobial peptides and the gut microbiome in inflammatory bowel disease

John Gubatan, Derek R Holman, Christopher J Puntasecca, Danielle Polevoi, Samuel JS Rubin, Stephan Rogalla

World J Gastroenterol 27(43):7402-7422. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7402

Abstract (788) | Core Tip (1000) | Full Article (HTML) (6889) | Tables (1-3) (607) | Full Article (PDF)-875K (636) | Audio-924K (10) | Peer-Review Report-243K (103) | Answering Reviewers-402K (109) | Received: 03/19/2021 | Revised: 05/13/2021 | Accepted: 11/15/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (59) | Total Visits (13396) | Similar Articles (628) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Idiopathic chronic pancreatitis: Beyond antioxidants

Rajiv M Mehta, Stephen J Pandol, Prachi R Joshi

World J Gastroenterol 27(43):7423-7432. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7423

Abstract (990) | Core Tip (711) | Full Article (HTML) (3704) | Figures (1-3) (327) | Full Article (PDF)-873K (394) | Audio-807K (4) | Peer-Review Report-196K (107) | Answering Reviewers-44K (114) | Received: 03/30/2021 | Revised: 07/05/2021 | Accepted: 10/27/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (6) | Total Visits (8610) | Similar Articles (98) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Opinion Review

COVID-19 as a trigger of irritable bowel syndrome: A review of potential mechanisms

Carlo Romano Settanni, Gianluca Ianiro, Francesca Romana Ponziani, Stefano Bibbò, Jonathan Philip Segal, Giovanni Cammarota, Antonio Gasbarrini

World J Gastroenterol 27(43):7433-7445. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7433

Abstract (829) | Core Tip (1076) | Full Article (HTML) (7147) | Figures (1-1) (560) | Full Article (PDF)-904K (863) | Audio-1199K (15) | Peer-Review Report-230K (200) | Answering Reviewers-122K (168) | Received: 03/04/2021 | Revised: 05/10/2021 | Accepted: 11/15/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (38) | Total Visits (14131) | Similar Articles (903) | Timeline of Article Publication (2) | Authors Evaluation (2) | Article Quality Tracking (3) | What about the content of this article? (0) | Cite |

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Review

Overview of the microbiota in the gut-liver axis in viral B and C hepatitis

Maria Adriana Neag, Andrei Otto Mitre, Adrian Catinean, Anca Dana Buzoianu

World J Gastroenterol 27(43):7446-7461. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7446

Abstract (734) | Core Tip (693) | Full Article (HTML) (3508) | Figures (1-2) (456) | Tables (1-2) (659) | Full Article (PDF)-1404K (452) | Audio-472K (9) | Peer-Review Report-304K (152) | Answering Reviewers-260K (130) | Received: 03/18/2021 | Revised: 08/13/2021 | Accepted: 11/03/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (12) | Total Visits (10004) | Similar Articles (7) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Hepatocellular carcinoma locoregional therapies: Outcomes and future horizons

Mina S Makary, Stuart Ramsell, Eric Miller, Eliza W Beal, Joshua D Dowell

World J Gastroenterol 27(43):7462-7479. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7462

Abstract (983) | Core Tip (631) | Full Article (HTML) (4080) | Figures (1-1) (338) | Tables (1-2) (445) | Full Article (PDF)-946K (530) | Audio-1281K (7) | Peer-Review Report-143K (147) | Answering Reviewers-74K (133) | Received: 04/23/2021 | Revised: 07/09/2021 | Accepted: 10/27/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (40) | Total Visits (9964) | Similar Articles (1688) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Minireviews

Recent advances in artificial intelligence for pancreatic ductal adenocarcinoma

Hiromitsu Hayashi, Norio Uemura, Kazuki Matsumura, Liu Zhao, Hiroki Sato, Yuta Shiraishi, Yo-ichi Yamashita, Hideo Baba

World J Gastroenterol 27(43):7480-7496. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7480

Abstract (808) | Core Tip (716) | Full Article (HTML) (3964) | Figures (1-2) (366) | Tables (1-1) (372) | Full Article (PDF)-1564K (521) | Audio-1725K (6) | Peer-Review Report-342K (178) | Answering Reviewers-92K (132) | Supplementary Material-119K (160) | Received: 04/03/2021 | Revised: 08/02/2021 | Accepted: 11/15/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (18) | Total Visits (10636) | Similar Articles (250) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Hepatitis B: Who should be treated?-managing patients with chronic hepatitis B during the immune-tolerant and immunoactive phases

Miwa Kawanaka, Ken Nishino, Hirofumi Kawamoto, Ken Haruma

World J Gastroenterol 27(43):7497-7508. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7497

Abstract (723) | Core Tip (678) | Full Article (HTML) (3527) | Tables (1-3) (438) | Full Article (PDF)-783K (464) | Audio-1531K (7) | Peer-Review Report-221K (137) | Answering Reviewers-78K (112) | Received: 04/23/2021 | Revised: 07/31/2021 | Accepted: 10/31/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (14) | Total Visits (8163) | Similar Articles (180) | Timeline of Article Publication (5) | Article Quality Tracking (2) | What about the content of this article? (0) | Cite |

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Basic Study

Liver injury changes the biological characters of serum small extracellular vesicles and reprograms hepatic macrophages in mice

Xiu-Fang Lv, An-Qi Zhang, Wei-Qi Liu, Min Zhao, Jing Li, Li He, Li Cheng, Yu-Feng Sun, Gang Qin, Peng Lu, Yu-Hua Ji, Ju-Ling Ji

World J Gastroenterol 27(43):7509-7529. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7509

Abstract (785) | Core Tip (817) | Article Highlights (575) | Full Article (HTML) (2804) | Figures (1-7) (604) | Tables (1-1) (321) | Full Article (PDF)-24863K (299) | Full Article (XML)-181K (46) | Audio-622K (8) | Peer-Review Report-201K (93) | Answering Reviewers-328K (100) | Supplementary Material-789K (176) | Received: 04/21/2021 | Revised: 07/21/2021 | Accepted: 09/16/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (8934) | Similar Articles (100) | Timeline of Article Publication (8) | Authors Evaluation (4) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Genome-wide map of N⁶-methyladenosine circular RNAs identified in mice model of severe acute pancreatitis

Jun Wu, Xiao-Hui Yuan, Wen Jiang, Yi-Chen Lu, Qi-Lin Huang, Yi Yang, Hua-Ji Qie, Jiang-Tao Liu, Hong-Yu Sun, Li-Jun Tang

World J Gastroenterol 27(43):7530-7545. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7530

Abstract (658) | Core Tip (624) | Article Highlights (668) | Full Article (HTML) (2899) | Figures (1-8) (288) | Tables (1-2) (613) | Full Article (PDF)-10938K (357) | Audio-663K (7) | Peer-Review Report-201K (144) | Answering Reviewers-892K (122) | Supplementary Material-118K (120) | Received: 05/19/2021 | Revised: 07/05/2021 | Accepted: 09/16/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (9) | Total Visits (8797) | Similar Articles (66) | Timeline of Article Publication (7) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Survivin-positive circulating tumor cells as a marker for metastasis of hepatocellular carcinoma

Jing Yu, Zhan Wang, Hua Zhang, Yi Wang, Dong-Qing Li

World J Gastroenterol 27(43):7546-7562. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7546

Abstract (688) | Core Tip (581) | Article Highlights (611) | Full Article (HTML) (2568) | Figures (1-10) (449) | Tables (1-1) (300) | Full Article (PDF)-20772K (313) | Audio-1027K (8) | Peer-Review Report-205K (96) | Answering Reviewers-2134K (109) | Supplementary Material-115K (119) | Received: 05/23/2021 | Revised: 07/19/2021 | Accepted: 10/27/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (9) | Total Visits (9695) | Similar Articles (1836) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (2) | What about the content of this article? (0) | Cite |

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Prospective Study

Immunoglobulin G in non-alcoholic steatohepatitis predicts clinical outcome: A prospective multi-centre cohort study

Marianne Anastasia De Roza, Mehul Lamba, George Boon-Bee Goh, Johnathan Huey-Ming Lum, Mark Chang-Chuen Cheah, Jing Hieng Jeffrey Ngu

World J Gastroenterol 27(43):7563-7571. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7563

Abstract (779) | Core Tip (644) | Article Highlights (952) | Full Article (HTML) (2447) | Figures (1-2) (337) | Tables (1-2) (309) | Full Article (PDF)-915K (309) | Audio-1547K (8) | Peer-Review Report-144K (94) | Answering Reviewers-119K (81) | Received: 04/19/2021 | Revised: 07/20/2021 | Accepted: 11/03/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (11) | Total Visits (8582) | Similar Articles (47) | Timeline of Article Publication (3) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Systematic Reviews

Minimum sample size estimates for trials in inflammatory bowel disease: A systematic review of a support resource

Morris Gordon, Svetlana Lakunina, Vasiliki Sinopoulou, Anthony Akobeng

World J Gastroenterol 27(43):7572-7581. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7572

Abstract (942) | Core Tip (765) | Article Highlights (641) | Full Article (HTML) (2155) | Figures (1-1) (297) | Tables (1-2) (674) | Full Article (PDF)-891K (310) | Audio-689K (3) | Peer-Review Report-242K (93) | Answering Reviewers-91K (112) | Supplementary Material-136K (129) | Received: 03/04/2021 | Revised: 06/30/2021 | Accepted: 10/31/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (11) | Total Visits (8789) | Similar Articles (604) | Timeline of Article Publication (0) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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