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Contents Volume 27 Issue 43 November 21, 2021

Frontier

Antimicrobial peptides and the gut microbiome in inflammatory bowel disease

John Gubatan, Derek R Holman, Christopher J Puntasecca, Danielle Polevoi, Samuel JS Rubin, Stephan Rogalla

World J Gastroenterol 27(43):7402-7422. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7402

Abstract (823) | Core Tip (1070) | Full Article (HTML) (7295) | Tables (1-3) (739) | Full Article (PDF)-875K (646) | Audio-924K (10) | Peer-Review Report-243K (110) | Answering Reviewers-402K (115) | Received: 03/19/2021 | Revised: 05/13/2021 | Accepted: 11/15/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (64) | Total Visits (14153) | Similar Articles (632) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Idiopathic chronic pancreatitis: Beyond antioxidants

Rajiv M Mehta, Stephen J Pandol, Prachi R Joshi

World J Gastroenterol 27(43):7423-7432. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7423

Abstract (1065) | Core Tip (755) | Full Article (HTML) (3867) | Figures (1-3) (371) | Full Article (PDF)-873K (403) | Audio-807K (4) | Peer-Review Report-196K (116) | Answering Reviewers-44K (121) | Received: 03/30/2021 | Revised: 07/05/2021 | Accepted: 10/27/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (6) | Total Visits (9037) | Similar Articles (98) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Opinion Review

COVID-19 as a trigger of irritable bowel syndrome: A review of potential mechanisms

Carlo Romano Settanni, Gianluca Ianiro, Francesca Romana Ponziani, Stefano Bibbò, Jonathan Philip Segal, Giovanni Cammarota, Antonio Gasbarrini

World J Gastroenterol 27(43):7433-7445. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7433

Abstract (869) | Core Tip (1142) | Full Article (HTML) (7313) | Figures (1-1) (629) | Full Article (PDF)-904K (873) | Audio-1199K (16) | Peer-Review Report-230K (209) | Answering Reviewers-122K (178) | Received: 03/04/2021 | Revised: 05/10/2021 | Accepted: 11/15/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (38) | Total Visits (14604) | Similar Articles (906) | Timeline of Article Publication (2) | Authors Evaluation (2) | Article Quality Tracking (3) | What about the content of this article? (0) | Cite |

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Review

Overview of the microbiota in the gut-liver axis in viral B and C hepatitis

Maria Adriana Neag, Andrei Otto Mitre, Adrian Catinean, Anca Dana Buzoianu

World J Gastroenterol 27(43):7446-7461. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7446

Abstract (790) | Core Tip (736) | Full Article (HTML) (3851) | Figures (1-2) (503) | Tables (1-2) (731) | Full Article (PDF)-1404K (465) | Audio-472K (9) | Peer-Review Report-304K (158) | Answering Reviewers-260K (136) | Received: 03/18/2021 | Revised: 08/13/2021 | Accepted: 11/03/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (12) | Total Visits (10703) | Similar Articles (7) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Hepatocellular carcinoma locoregional therapies: Outcomes and future horizons

Mina S Makary, Stuart Ramsell, Eric Miller, Eliza W Beal, Joshua D Dowell

World J Gastroenterol 27(43):7462-7479. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7462

Abstract (1068) | Core Tip (679) | Full Article (HTML) (4299) | Figures (1-1) (381) | Tables (1-2) (513) | Full Article (PDF)-946K (544) | Audio-1281K (8) | Peer-Review Report-143K (157) | Answering Reviewers-74K (144) | Received: 04/23/2021 | Revised: 07/09/2021 | Accepted: 10/27/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (41) | Total Visits (10570) | Similar Articles (1701) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Minireviews

Recent advances in artificial intelligence for pancreatic ductal adenocarcinoma

Hiromitsu Hayashi, Norio Uemura, Kazuki Matsumura, Liu Zhao, Hiroki Sato, Yuta Shiraishi, Yo-ichi Yamashita, Hideo Baba

World J Gastroenterol 27(43):7480-7496. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7480

Abstract (854) | Core Tip (767) | Full Article (HTML) (4246) | Figures (1-2) (411) | Tables (1-1) (445) | Full Article (PDF)-1564K (530) | Audio-1725K (7) | Peer-Review Report-342K (188) | Answering Reviewers-92K (139) | Supplementary Material-119K (168) | Received: 04/03/2021 | Revised: 08/02/2021 | Accepted: 11/15/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (18) | Total Visits (11280) | Similar Articles (254) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Hepatitis B: Who should be treated?-managing patients with chronic hepatitis B during the immune-tolerant and immunoactive phases

Miwa Kawanaka, Ken Nishino, Hirofumi Kawamoto, Ken Haruma

World J Gastroenterol 27(43):7497-7508. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7497

Abstract (760) | Core Tip (721) | Full Article (HTML) (3662) | Tables (1-3) (495) | Full Article (PDF)-783K (473) | Audio-1531K (7) | Peer-Review Report-221K (144) | Answering Reviewers-78K (118) | Received: 04/23/2021 | Revised: 07/31/2021 | Accepted: 10/31/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (14) | Total Visits (8535) | Similar Articles (180) | Timeline of Article Publication (5) | Article Quality Tracking (2) | What about the content of this article? (0) | Cite |

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Basic Study

Liver injury changes the biological characters of serum small extracellular vesicles and reprograms hepatic macrophages in mice

Xiu-Fang Lv, An-Qi Zhang, Wei-Qi Liu, Min Zhao, Jing Li, Li He, Li Cheng, Yu-Feng Sun, Gang Qin, Peng Lu, Yu-Hua Ji, Ju-Ling Ji

World J Gastroenterol 27(43):7509-7529. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7509

Abstract (853) | Core Tip (884) | Article Highlights (622) | Full Article (HTML) (2916) | Figures (1-7) (656) | Tables (1-1) (361) | Full Article (PDF)-24863K (306) | Full Article (XML)-181K (57) | Audio-622K (8) | Peer-Review Report-201K (101) | Answering Reviewers-328K (107) | Supplementary Material-789K (186) | Received: 04/21/2021 | Revised: 07/21/2021 | Accepted: 09/16/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (9455) | Similar Articles (101) | Timeline of Article Publication (8) | Authors Evaluation (4) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Genome-wide map of N⁶-methyladenosine circular RNAs identified in mice model of severe acute pancreatitis

Jun Wu, Xiao-Hui Yuan, Wen Jiang, Yi-Chen Lu, Qi-Lin Huang, Yi Yang, Hua-Ji Qie, Jiang-Tao Liu, Hong-Yu Sun, Li-Jun Tang

World J Gastroenterol 27(43):7530-7545. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7530

Abstract (712) | Core Tip (667) | Article Highlights (717) | Full Article (HTML) (3003) | Figures (1-8) (324) | Tables (1-2) (676) | Full Article (PDF)-10938K (369) | Audio-663K (7) | Peer-Review Report-201K (152) | Answering Reviewers-892K (129) | Supplementary Material-118K (126) | Received: 05/19/2021 | Revised: 07/05/2021 | Accepted: 09/16/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (9) | Total Visits (9275) | Similar Articles (66) | Timeline of Article Publication (7) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Survivin-positive circulating tumor cells as a marker for metastasis of hepatocellular carcinoma

Jing Yu, Zhan Wang, Hua Zhang, Yi Wang, Dong-Qing Li

World J Gastroenterol 27(43):7546-7562. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7546

Abstract (732) | Core Tip (641) | Article Highlights (669) | Full Article (HTML) (2671) | Figures (1-10) (508) | Tables (1-1) (326) | Full Article (PDF)-20772K (324) | Audio-1027K (8) | Peer-Review Report-205K (106) | Answering Reviewers-2134K (121) | Supplementary Material-115K (133) | Received: 05/23/2021 | Revised: 07/19/2021 | Accepted: 10/27/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (9) | Total Visits (10302) | Similar Articles (1850) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (2) | What about the content of this article? (0) | Cite |

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Prospective Study

Immunoglobulin G in non-alcoholic steatohepatitis predicts clinical outcome: A prospective multi-centre cohort study

Marianne Anastasia De Roza, Mehul Lamba, George Boon-Bee Goh, Johnathan Huey-Ming Lum, Mark Chang-Chuen Cheah, Jing Hieng Jeffrey Ngu

World J Gastroenterol 27(43):7563-7571. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7563

Abstract (837) | Core Tip (698) | Article Highlights (1028) | Full Article (HTML) (2551) | Figures (1-2) (378) | Tables (1-2) (353) | Full Article (PDF)-915K (317) | Audio-1547K (8) | Peer-Review Report-144K (101) | Answering Reviewers-119K (89) | Received: 04/19/2021 | Revised: 07/20/2021 | Accepted: 11/03/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (11) | Total Visits (9084) | Similar Articles (48) | Timeline of Article Publication (3) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Systematic Reviews

Minimum sample size estimates for trials in inflammatory bowel disease: A systematic review of a support resource

Morris Gordon, Svetlana Lakunina, Vasiliki Sinopoulou, Anthony Akobeng

World J Gastroenterol 27(43):7572-7581. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7572

Abstract (1016) | Core Tip (830) | Article Highlights (685) | Full Article (HTML) (2221) | Figures (1-1) (342) | Tables (1-2) (737) | Full Article (PDF)-891K (317) | Audio-689K (3) | Peer-Review Report-242K (99) | Answering Reviewers-91K (119) | Supplementary Material-136K (133) | Received: 03/04/2021 | Revised: 06/30/2021 | Accepted: 10/31/2021 | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (11) | Total Visits (9243) | Similar Articles (608) | Timeline of Article Publication (0) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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