Analysis of ocular structural parameters and higher-order aberrations in Chinese children with myopia

Table 1 Comparison of ocular structure parameters among children with low, middle, and high myopia

	Low myopia (mean ± SD)	Middle myopia (mean ± SD)	High myopia (mean ± SD)	F	P value
Spherical equivalent (D)	-1.69 ± 0.70	-3.86 ± 0.69	-7.55 ± 1.12	1572.765	< 0.001
AL (mm)	23.83 ± 0.75	24.63 ± 0.69	26.00 ± 0.94	259.188	< 0.001
R (mm)	7.77 ± 0.25	7.73 ± 0.24	7.74 ± 0.27	1.809	0.165
AL/R	3.07 ± 0.07	3.19 ± 0.08	3.37 ± 0.10	468.348	< 0.001
K1 (D)	42.95 ± 1.36	43.17 ± 1.27	43.07 ± 1.61	0.503	0.605
K2 (D)	43.89 ± 1.49	44.21 ± 1.37	44.46 ± 1.74	4.925	< 0.001
Km (D)	43.43 ± 1.42	43.69 ± 1.31	43.77 ± 1.67	1.933	0.146
CCT (μm)	561.52 ± 32.11	559.15 ± 23.58	552.85 ± 36.26	2.684	0.070
ACD (mm)	3.30 ± 0.17	3.33 ± 0.15	3.34 ± 0.17	2.450	0.088
ACA (°)	60.73 ± 5.84	59.19 ± 6.69	59.89 ± 7.27	1.253	0.287

AL: Axial length; CCT: Central corneal thickness; ACD: Anterior chamber depth; ACA: Anterior chamber angle.

Table 2 Comparison of higher-order aberrations among children with low, middle, and high myopia

	Total higher-order aberration (μm)	Spherical aberration (μm)	Coma aberration (μm)	Trefoil aberration (μm)
Low myopia	0.24 ± 0.12	0.06 ± 0.04	0.14 ± 0.07	0.13 ± 0.11
Middle myopia	0.24 ± 0.09	0.09 ± 0.04	0.13 ± 0.07	0.12 ± 0.07
High myopia	0.25 ± 0.13	0.07 ± 0.04	0.13 ± 0.06	0.14 ± 0.10
F	0.115	6.735	0.536	0.650
P value	0.891	< 0.001	0.585	0.523

Table 3 Analysis of correlation factors between diopter and structural parameters in low, middle, and high myopia

	Age	AL (mm)	K1 (D)	K2 (D)	Km (D)	ACD (mm)	CCT (mm)	ACA (°)
Low myopia
r	-0.153	-0.123	-0.251	-0.163	-0.204	0.193	0.075	-0.008
P value	0.073	0.148	0.003a	0.055	0.016a	0.023a	0.378	0.923
Middle myopia
r	-0.199	-0.388	-0.040	-0.137	-0.093	-0.242	0.017	-0.065
P value	0.131	0.002a	0.764	0.302	0.484	0.065	0.899	0.625
High myopia
r	-0.336	-0.405	-0.035	-0.094	-0.069	0.046	0.062	0.001
P value	< 0.001	< 0.001	0.662	0.240	0.387	0.565	0.438	0.986

^aP < 0.05. AL: Axial length; CCT: Central corneal thickness; ACD: Anterior chamber depth; ACA: Anterior chamber angle.