Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 26, 2021; 9(27): 8035-8043
Published online Sep 26, 2021. doi: 10.12998/wjcc.v9.i27.8035
Analysis of ocular structural parameters and higher-order aberrations in Chinese children with myopia
Xue Li, Qi Hu, Qian-Ru Wang, Zi-Qing Feng, Fan Yang, Chun-Yu Du
Xue Li, Fan Yang, Chun-Yu Du, Department of Ophthalmology, The Center of Optometry of The First Affiliated Hospital of Harbin Medical University, Harbin 150000, Heilongjiang Province, China
Qi Hu, Department of Ophthalmology, The Second Hospital of Shanxi Medical University, Taiyuan 030000, Shanxi Province, China
Qian-Ru Wang, Zi-Qing Feng, Department of Ophthalmology, Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen University, Guangzhou 510000, Guangdong Province, China
Author contributions: Li X and Hu Q contributed equally to this article and should be considered as co-first authors; Li X and Hu Q designed this retrospective study; Wang QR and Feng ZQ wrote this paper; Yang F and Du CY were responsible for sorting the data.
Supported by Scientific Research Project of Heilongjiang Health Commission, China, No. 2020-141.
Institutional review board statement: The study was reviewed and approved by the Center of Optometry of the First Affiliated Hospital of Harbin Medical University Institutional Review Board.
Informed consent statement: Informed consent was obtained from the patients.
Conflict-of-interest statement: No conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Xue Li, MD, Attending Doctor, Department of Ophthalmology, The Center of Optometry of The First Affiliated Hospital of Harbin Medical University, No. 23 Postal Street, Nangang District, Harbin 150000, Heilongjiang Province, China.
Received: April 15, 2021
Peer-review started: April 15, 2021
First decision: May 11, 2021
Revised: May 15, 2021
Accepted: July 26, 2021
Article in press: July 26, 2021
Published online: September 26, 2021
Research background

Patients with high myopia account for 0.5%-5.0% of the global population. Relevant studies predicted that by 2050, the global number of myopia and high-myopia patients will have reached 5 billion and 900 million, respectively.

Research motivation

An association between changes in ocular structural parameters and the development of myopia and their role in the development of myopia require elucidation.

Research objectives

To explore the progression of high myopia.

Research methods

This study included 195 children aged 6–17 years with myopia who underwent eye examination conducted by an ophthalmologist.

Research results

The diopter of high myopia was correlated with age and axial length (AL), and AL of high myopia was negatively correlated with K1, K2, and Km, and positively correlated with age and anterior chamber depth.

Research conclusions

There are differences in AL/R values between high myopia and low-middle myopia, which can be used for the classification of ametropia. The degree of myopia has some influence on higher-order aberrations.

Research perspectives

Changes in ocular structure parameters are closely related to the progression of myopia.