Value of optical coherence tomography measurement of macular thickness and optic disc parameters for glaucoma screening in patients with high myopia

Table 1 Comparison of baseline data between the three patient groups (mean ± SD, n)

Group	Age (yr)	Gender (male/female)	Equivalent sphere diameter (D)	Mean refraction (D)
Group A (n = 60)	36.45 ± 3.78	22/38	-1.78 ± 2.21	-0.44 ± 1.56
Group B (n = 66)	35.48 ± 3.24	30/36	-2.16 ± 2.15	0.65 ± 2.45
Group C (n = 70)	36.15 ± 3.12	36/34	-2.57 ± 2.45	-1.05 ± 2.15
F/χ2 value	1.384	2.858	1.949	1.430
P value	0.253	0.240	0.145	0.242

Table 2 Comparison of contrast sensitivity, color vision, and best-corrected visual acuity levels among three groups (mean ± SD, n)

Group	CS	CV	BCVA
Group A (n = 60)	96.45 ± 1.78	0.94 ± 0.08	0.97 ± 0.08
Group B (n = 66)	87.48 ± 1.24a	0.81 ± 0.05a	0.87 ± 0.15a
Group C (n = 70)	89.15 ± 1.12a,b	0.87 ± 0.02a,b	0.91 ± 0.11a,b
F value	32.163	90.314	11.430
P value	0.000	0.000	0.000

^aP < 0.05 vs group A.

^bP < 0.05 vs group B.

CS: Contrast sensitivity; CV: Color vision; BCVA: Best-corrected visual acuity.

Table 3 Comparison of weekly parameters in the three groups (mean ± SD, n)

Group	Optic cup area (mm)	Optic disc area (mm)	Cup/disc area ratio	Cup/disc diameter ratio
Group A (n = 60)	1.02 ± 0.81	2.82 ± 0.88	0.34 ± 0.21	0.56 ± 0.05
Group B (n = 66)	1.31 ± 0.75a	3.87 ± 0.87a	0.37 ± 0.22	0.61 ± 0.06a
Group C (n = 70)	1.42 ± 0.65a	3.45 ± 0.75a,b	0.35 ± 0.18	0.59 ± 0.04a,b
F value	4.890	25.691	0.369	15.672
P value	0.009	0.000	0.692	0.000

^aP < 0.05 vs group A.

^bP < 0.05 vs group B.

Table 4 Retinal nerve fiber layer thickness in each of the three groups (mean ± SD, n)

Group	Complete cycle (μm)	Upper quadrant (μm)	Lower quadrant (μm)	Temporal side (μm)	nasal side (μm)
Group A (n = 60)	109.12 ± 10.54	133.23 ± 7.87	130.23 ±5.54	111.23 ± 5.36	60.45 ± 3.45
Group B (n = 66)	102.78 ± 9.23a	125.65 ± 7.54a	121.32 ± 5.45a	123.45 ± 5.21a	56.45 ± 2.98a
Group C (n = 70)	106.45 ± 10.21a,b	129.87 ± 8.56a,b	127.63 ± 5.78a,b	115.46 ± 5.14a,b	58.45 ± 2.12a,b
F value	4.212	14.177	42.888	89.611	30.552
P value	0.016	0	0	0	0

^aP < 0.05 vs group A.

^bP < 0.05 vs group B.

Table 5 Comparison of mean ganglion cell layer thickness and general loss of volume and focal loss of volume in the three groups (mean ± SD, n)

Group	Upper GCC (μm)	Bottom GCC (μm)	Mean GCC (μm)	GLV (%)	FLV (%)
Group A (n = 60)	94.15 ± 6.78	92.45 ± 7.45	92.56 ± 7.45	5.16 ± 4.12	1.36 ± 1.12
Group B (n = 66)	71.45 ± 6.56a	78.26 ± 11.65a	73.66 ± 8.12a	23.15 ± 8.97a	7.54 ± 4.85a
Group C (n = 70)	83.54 ± 5.54a,b	82.64 ± 8.78a,b	82.43 ± 8.26a,b	15.05 ± 8.78a,b	3.88 ± 2.56a,b
F value	205.836	36.474	88.326	85.061	57.448
P value	0	0	0	0	0

^aP < 0.05 vs group A.

^bP < 0.05 vs group B.

GCC: Ganglion cell layer; GLV: General loss of volume; FLV: Focal loss of volume.