Huang YM, Zhuang Y, Tan ZM. Changes in rheumatoid arthritis under ultrasound before and after sinomenine injection. World J Clin Cases 2022; 10(1): 35-42 [PMID: 35071503 DOI: 10.12998/wjcc.v10.i1.35]
Corresponding Author of This Article
Zhi-Ming Tan, BM BCh, Chief Doctor, Department of Rheumatology and Immunology, Huizhou Central People’s Hospital, No. 41 Eling North Road, Huicheng District, Huizhou 516001, Guangdong Province, China. 3582027891@qq.com
Research Domain of This Article
Rheumatology
Article-Type of This Article
Case Control Study
Open-Access Policy of This Article
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World J Clin Cases. Jan 7, 2022; 10(1): 35-42 Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.35
Table 1 Comparison of therapeutic effects, n (%)
Group
Number of cases
Significantly effective
Improved
Ineffective
Total effective rate
Study group
47
29 (61.70)
15 (31.91)
3 (6.38)
44 (93.62)
Control group
47
21 (44.68)
16 (34.04)
10 (21.28)
37 (78.72)
χ2 value
4.374
P value
0.036
Table 2 Comparison of synovial membrane thickness and visual analog scale scores
Timing
Group
Number of cases
Synovial thickness (mm, mean ± SD)
VAS score (mean ± SD)
Before treatment
Study group
47
5.29 ± 1.44
7.01 ± 1.38
Control group
47
5.50 ± 1.32
6.89 ± 1.50
t value
0.737
0.404
P value
0.463
0.687
After treatment
Study group
47
2.05 ± 0.59
2.11 ± 0.62
Control group
47
2.87 ± 0.64
2.90 ± 0.79
t value
6.458
5.393
P value
0.000
0.000
Table 3 Comparison of blood flow classification, n (%)
Timing
Group
Number of cases
Grade 0
Grade I
Grade II
Grade III
Before treatment
Study group
47
25 (53.19)
12 (25.53)
7 (14.89)
3 (6.38)
Control group
47
23 (48.94)
15 (31.91)
5 (10.64)
4 (8.51)
χ2 value
0.170
0.468
0.382
0.000
P value
0.680
0.494
0.536
1.000
After treatment
Study group
47
36 (76.60)
5 (10.64)
5 (10.64)
1 (2.13)
Control group
47
27 (57.45)
15 (31.91)
3 (6.38)
2 (4.26)
χ2 value
3.899
6.351
0.545
0.000
P value
0.048
0.012
0.460
1.000
Table 4 Comparison of arthro-inflammatory indexes (mean ± SD)
Timing
Group
Number of cases
RF (U/mL)
CRP (mg/L)
ESR (mm/h)
Beforetreatment
Study group
47
161.39 ± 15.06
34.10 ± 6.99
80.71 ± 7.11
Control group
47
158.91 ± 12.79
32.63 ± 7.29
78.65 ± 6.70
t value
0.861
0.998
1.446
P value
0.392
0.321
0.152
Aftertreatment
Study group
47
55.61 ± 6.13
11.43 ± 3.59
29.60 ± 5.56
Control group
47
73.04 ± 9.23
15.07 ± 4.06
36.64 ± 6.10
t value
10.785
4.605
5.848
P value
0.000
0.000
0.000
Citation: Huang YM, Zhuang Y, Tan ZM. Changes in rheumatoid arthritis under ultrasound before and after sinomenine injection. World J Clin Cases 2022; 10(1): 35-42