Huang YM, Zhuang Y, Tan ZM. Changes in rheumatoid arthritis under ultrasound before and after sinomenine injection. World J Clin Cases 2022; 10(1): 35-42 [PMID: 35071503 DOI: 10.12998/wjcc.v10.i1.35]
Corresponding Author of This Article
Zhi-Ming Tan, BM BCh, Chief Doctor, Department of Rheumatology and Immunology, Huizhou Central People’s Hospital, No. 41 Eling North Road, Huicheng District, Huizhou 516001, Guangdong Province, China. 3582027891@qq.com
Research Domain of This Article
Rheumatology
Article-Type of This Article
Case Control Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jan 7, 2022; 10(1): 35-42 Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.35
Changes in rheumatoid arthritis under ultrasound before and after sinomenine injection
Yi-Min Huang, Yu Zhuang, Zhi-Ming Tan
Yi-Min Huang, Yu Zhuang, Zhi-Ming Tan, Department of Rheumatology and Immunology, Huizhou Central People’s Hospital, Huizhou 516001, Guangdong Province, China
Author contributions: Huang YM design the experiment; Zhuang Y drafted the work, Tan ZM collected the data; Huang YM analysed and interpreted data, Zhuang Y and Tan ZM wrote the article.
Institutional review board statement: This study was approved by the Huizhou Central People’s Hospital Ethics Committee.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declared that there is no conflict of interest between them.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement, and the manuscript was prepared and revised according to the STROBE Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhi-Ming Tan, BM BCh, Chief Doctor, Department of Rheumatology and Immunology, Huizhou Central People’s Hospital, No. 41 Eling North Road, Huicheng District, Huizhou 516001, Guangdong Province, China. 3582027891@qq.com
Received: August 26, 2021 Peer-review started: August 26, 2021 First decision: September 29, 2021 Revised: October 14, 2021 Accepted: November 26, 2021 Article in press: November 26, 2021 Published online: January 7, 2022 Processing time: 125 Days and 21.4 Hours
ARTICLE HIGHLIGHTS
Research background
Rheumatoid arthritis (RA) is a popular clinical autoimmune disease. Diclofenac and methotrexate are usually used for treatment. In recent years, the application of Chinese medicine in RA has received widespread attention. The role of alkali preparations in this field has also received attention.
Research motivation
Explore the treatment methods of RA and broaden the application of Chinese medicine treatment in the field of RA.
Research objectives
This study aimed to study the therapeutic value of sinomenine preparations for RA.
Research methods
A total of 94 RA patients who received treatment from January 2019 to January 2021 were selected for a case-control study.
Research results
The total effective rate of the study group was higher than that of the control group.
Research conclusions
Sinomenine administration of Zhengqing Fengtongning in the articular cavity with conventional treatment of RA can improve ultrasonographic blood flow and synovial thickness, reduce pain, regulate inflammation, and enhance therapeutic effect.
Research perspectives
Sinomenine preparations can have a wider range of applications in the treatment of RA.
