Case Control Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 7, 2022; 10(1): 35-42
Published online Jan 7, 2022. doi: 10.12998/wjcc.v10.i1.35
Changes in rheumatoid arthritis under ultrasound before and after sinomenine injection
Yi-Min Huang, Yu Zhuang, Zhi-Ming Tan
Yi-Min Huang, Yu Zhuang, Zhi-Ming Tan, Department of Rheumatology and Immunology, Huizhou Central People’s Hospital, Huizhou 516001, Guangdong Province, China
Author contributions: Huang YM design the experiment; Zhuang Y drafted the work, Tan ZM collected the data; Huang YM analysed and interpreted data, Zhuang Y and Tan ZM wrote the article.
Institutional review board statement: This study was approved by the Huizhou Central People’s Hospital Ethics Committee.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declared that there is no conflict of interest between them.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement, and the manuscript was prepared and revised according to the STROBE Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhi-Ming Tan, BM BCh, Chief Doctor, Department of Rheumatology and Immunology, Huizhou Central People’s Hospital, No. 41 Eling North Road, Huicheng District, Huizhou 516001, Guangdong Province, China. 3582027891@qq.com
Received: August 26, 2021
Peer-review started: August 26, 2021
First decision: September 29, 2021
Revised: October 14, 2021
Accepted: November 26, 2021
Article in press: November 26, 2021
Published online: January 7, 2022
Core Tip

Core Tip: Sinomenine administration of Zhengqing Fengtongning in the articular cavity can improve blood flow and synovial thickness, reduce pain, regulate inflammation, and enhance therapeutic effect. The drug preparation was administered with diclofenac and methotrexate. Comparison of outcomes was done between a study group and a matched control group.