Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2021; 9(8): 1989-1995
Published online Mar 16, 2021. doi: 10.12998/wjcc.v9.i8.1989
Laryngopharyngeal reflux disease management for recurrent laryngeal contact granuloma: A case report
Kai Li, Wen-Yong Chen, Yun-Ying Li, Tu-Lu Wang, Meng-Jia Tan, Zong Chen, Hai Chen
Kai Li, Wen-Yong Chen, Yun-Ying Li, Tu-Lu Wang, Meng-Jia Tan, Zong Chen, Hai Chen, Department of Otorhinolaryngology, The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong Province, China
Author contributions: Li K, Chen WY and Wang TL were the patient’s otolaryngologists, reviewed the literature and contributed to manuscript drafting; Li YY reviewed the literature and contributed to manuscript drafting; Tan MJ and Chen Z performed laryngoscopy for this patient; Chen H was responsible for revision of the manuscript for important intellectual content; All authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors have no funding, financial relationships, or conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hai Chen, MM, Assistant Professor, Doctor, Department of Otorhinolaryngology, The Second Clinical College of Guangzhou University of Chinese Medicine, Dade Road, Yuexiu District, Guangzhou 510000, Guangdong Province, China. cnchenhai@gzucm.edu.cn
Received: November 16, 2020
Peer-review started: November 16, 2020
First decision: December 24, 2020
Revised: January 5, 2021
Accepted: January 8, 2021
Article in press: January 8, 2021
Published online: March 16, 2021
Core Tip

Core Tip: Laryngeal contact granuloma (LCG) is difficult to treat and frequently associated with high persistence and recurrence. We describe a patient with recurrent LCG in which a good response was achieved through successful management of laryngopharyngeal reflux disease using a combination pharmacotherapeutic regimen consisting of anti-reflux therapy, pepsin secretion inhibition, bile acid neutralization, and lifestyle modifications. The drug regimen was discontinued after one year, and no recurrence was observed during the one-year follow-up period. This case report highlights the efficacy of combined pharmacotherapeutics and lifestyle modifications in managing laryngopharyngeal reflux disease to address recurring LCG.