Clinical Trials Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 16, 2021; 9(29): 8740-8748
Published online Oct 16, 2021. doi: 10.12998/wjcc.v9.i29.8740
Effects of mindful breathing combined with sleep-inducing exercises in patients with insomnia
Hui Su, Li Xiao, Yue Ren, Hui Xie, Xiang-Hong Sun
Hui Su, Li Xiao, Yue Ren, Hui Xie, Xiang-Hong Sun, Sleep Medicine Center, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Author contributions: Su H and Sun XH designed the research study; Su H, Xiao L and Ren Y performed the research; Su H, Xie H, and Sun XH analyzed the data and wrote the manuscript; All authors have read and approve the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Shengjing Hospital of China Medical University (approval No 2019PS582K).
Clinical trial registration statement: The study is registered at Chinese Clinical Trial Registry. The registration identification number is: ChiCTR2100049927 and URL for the registry is: https://www.chictr.org.cn/showproj.aspx?proj=131839.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No relevant conflicts of interest.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at sunxh@sj-hospital.org.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiang-Hong Sun, MD, Chief Nurse, Sleep Medicine Center, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110004, Liaoning Province, China. 750019113@qq.com
Received: April 21, 2021
Peer-review started: April 21, 2021
First decision: June 24, 2021
Revised: July 6, 2021
Accepted: August 23, 2021
Article in press: August 23, 2021
Published online: October 16, 2021
Processing time: 177 Days and 1.8 Hours
Core Tip

Core Tip: The adjunctive therapies of mindful breathing and a sleep-inducing exercise could improve the outcome of patients with insomnia by providing a simple, cost-effective, and easy-to-implement method that can be used both clinically and long-term in a home setting. The findings indicated that compared with the control group, the group that performed mindful breathing and a sleep-inducing exercise in conjunction with routine pharmacological and physical therapies exhibited significant improvements in sleep quality, daytime functioning, negative emotions, sleep latency, sleep duration, sleep efficiency, anxiety level, and insomnia severity at 1 and 3 mo after the intervention (P < 0.05).