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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 6, 2021; 9(25): 7372-7380
Published online Sep 6, 2021. doi: 10.12998/wjcc.v9.i25.7372
Published online Sep 6, 2021. doi: 10.12998/wjcc.v9.i25.7372
Mucin 1 and interleukin-11 protein expression and inflammatory reactions in the intestinal mucosa of necrotizing enterocolitis children after surgery
Hong-Xia Pan, Min-Min Chen, Department of Clinical Laboratory Medicine, Suzhou BenQ Medical Center, Affiliated BenQ Hospital of Nanjing Medical University, Suzhou 215011, Jiangsu Province, China
Chang-Song Zhang, Department of Clinical Laboratory Medicine, The Affiliated Suzhou Science and Technology Town Hospital, Nanjing Medical University, Suzhou 215153, Jiangsu Province, China
Chia-Hui Lin, General Manager's Office, Suzhou Gallant Biotech Biotechnology Co. Ltd, Suzhou 215163, Jiangsu Province, China
Xiao-Zhong Zhang, Department of Cardiology, National High Tech Development Zone Hospital, Suzhou 215129, Jiangsu Province, China
Nong Yu, Department of Laboratory Medicine, National High Tech Development Zone Hospital, Suzhou 215129, Jiangsu Province, China
Author contributions: Pan HX and Zhang CS have the same contribution to this article and should be regarded as co-first authors; Pan HX and Zhang CS design the experiment; Lin CH drafted the work, Chen MM, Zhang XZ and Yu N collected the data; Pan HX and Zhang CS interpreted data; Pan HX, Zhang CS and Yu N wrote the article.
Supported by Suzhou Science and Technology Program , No. SLT202005 ; Suzhou Municipal Commission of Health and Family Planning , No. LCZX202031 ; Suzhou New District Science and Technology Plan , No. 2019Z009 ; and Independent Innovation Project of National High Tech Development Zone Hospital , No. SGY2018C03 .
Institutional review board statement: This study was approved by the Affiliated BenQ Hospital of Nanjing Medical University Ethics Committee.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: No conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nong Yu, BM BCh, Chief Technician, Department of Laboratory Medicine, National High Tech Development Zone Hospital, No. 95 Huashan Road, Huqiu District, Suzhou 215129, Jiangsu Province, China. yunong78612@sina.com
Received: April 22, 2021
Peer-review started: April 22, 2021
First decision: May 24, 2021
Revised: June 28, 2021
Accepted: July 28, 2021
Article in press: July 28, 2021
Published online: September 6, 2021
Peer-review started: April 22, 2021
First decision: May 24, 2021
Revised: June 28, 2021
Accepted: July 28, 2021
Article in press: July 28, 2021
Published online: September 6, 2021
Core Tip
Core Tip: This study analyzed the expression changes of mucin 1 and interleukin-11 in intestinal mucosa after necrotizing enterocolitis operation in neonatal necrotizing enterocolitis. It may be related to the pathogenesis of the disease, and providing clinical guidance and basis.