Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 16, 2021; 9(23): 6810-6815
Published online Aug 16, 2021. doi: 10.12998/wjcc.v9.i23.6810
Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature
Lei Tian, Li-Ya He, Hong-Zhen Zhang
Lei Tian, Li-Ya He, Hong-Zhen Zhang, Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, Hebei Province, China
Author contributions: Tian L reviewed the literature and wrote the manuscript; He LY was the patient’s doctor in charge; Zhang HZ contributed to the literature review; and all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Zhen Zhang, PhD, Doctor, Department of Oncology, Hebei General Hospital, No. 348 Heping West Road, Shijiazhuang 050051, China. 1256596529@qq.com
Received: February 1, 2021
Peer-review started: February 1, 2021
First decision: April 25, 2021
Revised: May 6, 2021
Accepted: May 19, 2021
Article in press: May 19, 2021
Published online: August 16, 2021
Core Tip

Core Tip: Nedaplatin has been shown to be an effective drug in a variety of cancers. Due to its wide application, it is important to pay attention to its side effects, especially rare side effects. Here, we report a case of a severe, rare syndrome of inappropriate secretion of antidiuretic hormone after initiating nedaplatin chemotherapy. Timely diagnosis, fluid restriction and sodium supplementation may be the most appropriate treatments.