Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2021; 9(21): 6091-6101
Published online Jul 26, 2021. doi: 10.12998/wjcc.v9.i21.6091
Diagnosis and treatment discussion of congenital factor VII deficiency in pregnancy: A case report
Ying Yang, Ya-Chang Zeng, Pingkan Rumende, Chen-Guang Wang, Yue Chen
Ying Yang, Ya-Chang Zeng, Pingkan Rumende, Chen-Guang Wang, Yue Chen, Department of Obstetrics, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Author contributions: Zeng YC, Chen Y, and Wang CG were the patient’s obstetricians; Yang Y reviewed the literature and contributed to manuscript drafting; Zeng YC, Yang Y, Chen Y, and Rumende P were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.
Supported by Natural Science Foundation of Guangxi, No. 2018JJB140171; Medical Excellence Award Funded by the Creative Research Development Grant from the First Affiliated Hospital of Guangxi Medical University (2020); Development and Application of Appropriate Medical and Health Technologies in Guangxi, No. S2018111; and Self-funded Scientific Research Project of Guangxi Health Commission, No. Z20190512.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yue Chen, MD, Chief Doctor, Department of Obstetrics, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuang Yong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China. 1254500940@qq.com
Received: March 22, 2021
Peer-review started: March 22, 2021
First decision: April 29, 2021
Revised: May 9, 2021
Accepted: May 26, 2021
Article in press: May 26, 2021
Published online: July 26, 2021
Core Tip

Core Tip: The clinical manifestations of congenital factor VII deficiency vary greatly and range from a mild asymptomatic case to fatal bleeding. During pregnancy, predicting the risk of bleeding during and after childbirth of pregnant women with congenital factor VII deficiency is difficult, causing serious challenges to obstetricians and gynecologists. We hereby report a case of a pregnant woman with congenital factor VII deficiency and discuss the perinatal period and delivery management of this disease.