Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2021; 9(20): 5730-5736
Published online Jul 16, 2021. doi: 10.12998/wjcc.v9.i20.5730
Hemorrhagic transformation of ischemic cerebral proliferative angiopathy: A case report
Yu Xia, Xian-Feng Yu, Zhen-Juan Ma, Zhong-Wu Sun
Yu Xia, Xian-Feng Yu, Zhen-Juan Ma, Zhong-Wu Sun, Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China
Author contributions: Xia Y was the patient’s neurosurgeon, reviewed the literature and contributed to manuscript drafting; Yu XF reviewed the literature and contributed to manuscript drafting; Ma ZJ analyzed and interpreted the imaging findings; Sun ZW were responsible for the revision of the manuscript for important intellectual content; All authors issued final approval for the version to be submitted.
Supported by National Natural Science Foundation of China, No. 81771154.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhong-Wu Sun, MD, Doctor, Department of Neurology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei 230022, Anhui Province, China. sunzhwu@126.com
Received: March 11, 2021
Peer-review started: March 11, 2021
First decision: March 25, 2021
Revised: April 6, 2021
Accepted: May 6, 2021
Article in press: May 6, 2021
Published online: July 16, 2021
Core Tip

Core Tip: This article reports a very rare case of ischemic cerebrovascular disease, namely ischemic cerebral proliferative angiopathy. After consulting major databases, we found that cases of ischemic and hemorrhagic cerebral proliferative angiopathy have been reported, but the biggest feature of this case is the phenomenon of hemorrhagic transformation after ischemia. So far, there are few reports of such diseases globally, and their pathogenesis is currently unclear. The diagnosis and treatment methods are limited. Therefore, this article reviews relevant literature to better understand this rare disease and provides clues for further clinical research.