Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 6, 2021; 9(19): 5319-5324
Published online Jul 6, 2021. doi: 10.12998/wjcc.v9.i19.5319
Four-year-old anti-N-methyl-D-aspartate receptor encephalitis patient with ovarian teratoma: A case report
Cong-Ying Xue, Hui Dong, Hui-Xia Yang, Yu-Wu Jiang, Ling Yin
Cong-Ying Xue, Hui-Xia Yang, Ling Yin, Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China
Hui Dong, Yu-Wu Jiang, Department of Pediatrics, Peking University First Hospital, Beijing 100034, China
Author contributions: Xue CY wrote the manuscript; Dong H was the attending pediatrician for the patient and revised the manuscript; Yang HX designed the study and managed the writing; Jiang YW revised the manuscript; Yin L performed the surgical operation and revised the manuscript critically for important intellectual content; all authors read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the parents of the child for the surgery and publication of this case report.
Conflict-of-interest statement: The authors claim no conflict of interest related to this manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016) and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ling Yin, MD, Chief Doctor, Department of Obstetrics and Gynecology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China. yinling6565@sina.com
Received: February 27, 2021
Peer-review started: February 27, 2021
First decision: April 14, 2021
Revised: April 25, 2021
Accepted: May 7, 2021
Article in press: May 7, 2021
Published online: July 6, 2021
Processing time: 116 Days and 12.2 Hours
Core Tip

Core Tip: In this case report, we describe the successful treatment of anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis by early laparoscopic teratoma removal and immunotherapy in a 4-year-old female child. And to the best of our knowledge, this detailed case report is about the youngest patient to date with anti-NMDAR encephalitis who underwent laparoscopic ovarian cystectomy. We intend to increase awareness about the importance of early identification of anti-NMDAR encephalitis and once the disease is diagnosed, it should be screened for tumor, especially ovarian teratoma, and surgical intervention should be adopted as soon as possible.