Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2021; 9(16): 3951-3959
Published online Jun 6, 2021. doi: 10.12998/wjcc.v9.i16.3951
Rehabilitation and pharmacotherapy of neuromyelitis optica spectrum disorder: A case report
Xiao-Ju Wang, Peng Xia, Ting Yang, Kai Cheng, An-Liang Chen, Xue-Ping Li
Xiao-Ju Wang, Peng Xia, Ting Yang, Kai Cheng, An-Liang Chen, Xue-Ping Li, Department of Rehabilitation Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, Jiangsu Province, China
Author contributions: Wang XJ and Xia P contributed equally to this article; Wang XJ wrote the manuscript; Xia P contributed to the data acquisition; Yang T and Cheng K followed the patient during treatment; Li XP and Chen AL revised the manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue-Ping Li, PhD, Chief Doctor, Department of Rehabilitation Medicine, Nanjing First Hospital, Nanjing Medical University, No. 68 Changle Road, Nanjing 210006, Jiangsu Province, China. lixueping2020@njmu.edu.cn
Received: November 22, 2020
Peer-review started: November 22, 2020
First decision: December 24, 2020
Revised: January 2, 2021
Accepted: March 5, 2021
Article in press: March 5, 2021
Published online: June 6, 2021
Processing time: 160 Days and 19 Hours
Core Tip

Core Tip: Neuromyelitis optica spectrum disorder (NMOSD) is a demyelinating autoimmune disorder of the central nervous system. It typically manifests as optic neuritis or extensive longitudinal myelitis, with or without the presence of anti-aquaporin protein 4 autoantibodies (immunoglobulin G). We report the case of a 45-year-old woman with a history of Sjogren's syndrome who was diagnosed with NMOSD accompanied by spinal cord injury and left calf intermuscular vein thrombosis. The patient received hormone shock and gamma globulin therapy in the acute phase and standard rehabilitation treatment during convalescence.