Differential analysis revealing APOC1 to be a diagnostic and prognostic marker for liver metastases of colorectal cancer
Hai-Yu Shen, Fang-Ze Wei, Qian Liu, Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Author contributions: Shen HY, Wei FZ, and Liu Q designed the research, collected and analyzed the data, and drafted and revised the article; all authors have read and approved the final manuscript.
Supported by National Key Research and Development (R&D) Program Project, No. 2019YFC1315705.
Institutional review board statement: The study was reviewed and approved by the Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College Institutional Review Board (approval No. 17-116/1439).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that there is no conflict of interest in regard to this research.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at fcwpumch@163.com.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
http://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Qian Liu, MD, Chief Doctor, Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. fcwpumch@163.com
Received: January 22, 2021
Peer-review started: January 22, 2021
First decision: February 28, 2021
Revised: March 10, 2021
Accepted: March 23, 2021
Article in press: March 23, 2021
Published online: June 6, 2021
