Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 26, 2019; 7(6): 792-797
Published online Mar 26, 2019. doi: 10.12998/wjcc.v7.i6.792
Effective chemotherapy for submandibular gland carcinoma ex pleomorphic adenoma with lung metastasis after radiotherapy: A case report
Zhi-Yuan Chen, Yu Zhang, Yan Tu, Wei Zhao, Mei Li
Zhi-Yuan Chen, Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Yu Zhang, Oncology Department, the Second People’s Hospital of Yunnan Province, Kunming 650000, Yunan Province, China
Yan Tu, Radiology Department, Yunnan Tumor Hospital, Kunming 650000, Yunan Province, China
Wei Zhao, Pathology Department, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Mei Li, Department of Head & Neck Cancer, Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Li M designed the study; Tu Y and Zhao W contributed to the acquisition of data; Zhang Y and Chen ZY wrote the paper; Chen ZY and Zhang Y contributed equally to this work; all authors approved the final version of the manuscript.
Informed consent statement: Consent was obtained from the patient’s son for publication of this report and accompanying images.
Conflict-of-interest statement: All the authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Mei Li, MD, Associate Chief Physician, Department of Head & Neck Cancer, Cancer Center, West China Hospital, Sichuan University, No. 37, Guoxue Lane, Chengdu 610041, China. limeiscu78@163.com
Telephone: +86-28-85423278 Fax: +86-28-85423278
Received: December 13, 2018
Peer-review started: December 13, 2018
First decision: January 12, 2019
Revised: February 16, 2019
Accepted: February 26, 2019
Article in press: February 26, 2019
Published online: March 26, 2019
Processing time: 103 Days and 6.8 Hours
Core Tip

Core tip: The standard treatment for salivary gland carcinoma ex pleomorphic adenoma is surgical resection combined with postoperative radiotherapy, but the necessity of chemotherapy as well as the most appropriate treatment regimen for patients with distant metastasis after radiotherapy remains controversial. The positive clinical outcome in this case reveals that this chemotherapy regimen may be an alternative treatment for such a condition.