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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 26, 2019; 7(18): 2704-2711
Published online Sep 26, 2019. doi: 10.12998/wjcc.v7.i18.2704
Published online Sep 26, 2019. doi: 10.12998/wjcc.v7.i18.2704
Analgesic effect of parecoxib combined with ropivacaine in patients undergoing laparoscopic hepatectomy
Shan-Shan Huang, Shao-Zhong Yang, Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province, China
Wei-Wei Lv, Department of Radiology, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province, China
Yan-Feng Liu, Department of General Surgery, Qilu Hospital of Shandong University, Jinan 250012, Shandong Province, China
Author contributions: Huang SS and Lv WW contributed equally to this work and should be considered as co-first authors; Yang SZ and Liu YF designed and performed the research; Yang SZ and Lv WW analyzed the data and wrote the paper.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Qilu Hospital of Shandong University.
Informed consent statement: All the patients provided informed consent.
Conflict-of-interest statement: No conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Shao-Zhong Yang, MD, MSc, Attending Doctor, Department of Anesthesiology, Qilu Hospital of Shandong University, Cultural West Road, Lixia District, Jinan 250012, Shandong Province, China. yszyang@163.com
Telephone: +86-531-82166458 Fax: +86-531-82166471
Received: June 15, 2019
Peer-review started: June 18, 2019
First decision: July 30, 2019
Revised: August 19, 2019
Accepted: August 26, 2019
Article in press: August 26, 2019
Published online: September 26, 2019
Peer-review started: June 18, 2019
First decision: July 30, 2019
Revised: August 19, 2019
Accepted: August 26, 2019
Article in press: August 26, 2019
Published online: September 26, 2019
Core Tip
Core tip: Forty-eight patients undergoing laparoscopic hepatectomy were randomly divided into a combined group (parecoxib combined with ropivacaine) and a control group. A visual analogue scale at rest and during movement was used to compare the analgesic effect of the two groups. Preoperative intravenous injection of parecoxib combined with the long-acting local anesthetic ropivacaine for incision infiltration is a simple and effective method for postoperative analgesia in patients undergoing laparoscopic hepatectomy, which could relieve postoperative pain and promote postoperative recovery.