Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 16, 2023; 11(23): 5455-5461
Published online Aug 16, 2023. doi: 10.12998/wjcc.v11.i23.5455
Serum vascular endothelial growth factor and cortisol expression to predict prognosis of patients with hypertensive cerebral hemorrhage
Chao-Yong Zhang, Bin Wang, Xiang-Ting Hua, Kui Fan, Yu-Feng Li
Chao-Yong Zhang, Xiang-Ting Hua, Kui Fan, Yu-Feng Li, Department of Neurosurgery, Taihe Hospital Affiliated to Wannan Medical College, Taihe County People’s Hospital, Fuyang 236600, Anhui Province, China
Bin Wang, Department of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui Province, China
Author contributions: Zhang CY and Wang B contributed equally to this work; Zhang CY, Wang B, Hua XT, Fan K, and Li YF, designed the research study; Zhang CY, Wang B, Hua XT, and Fan K performed the research; Zhang CY, Wang B, and Li YF analyzed the data and wrote the manuscript; All authors have read and approve the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Taihe Hospital Affiliated to Wannan Medical College Institutional Review Board.
Informed consent statement: This study has signed an informed consent form with the patient.
Conflict-of-interest statement: All authors have no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bin Wang, Doctor, Chief Doctor, Department of Neurosurgery, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei 230000, Anhui Province, China. hulier888@163.com
Received: June 6, 2023
Peer-review started: June 6, 2023
First decision: June 21, 2023
Revised: June 26, 2023
Accepted: July 14, 2023
Article in press: July 14, 2023
Published online: August 16, 2023
Core Tip

Core Tip: Investigation of the correlation between vascular endothelial growth factor (VEGF) and cortisol (Cor) levels and the prognosis of patients with hypertensive intracerebral hemorrhage indicated that Cor and VEGF are associated with the occurrence and development of cerebral hemorrhage, as well as neurological impairment and patient prognosis. Thus, Cor and VEGF may act as potential biomarkers for predicting the prognosis of patients with hypertensive intracerebral hemorrhage.