Published online Aug 16, 2023. doi: 10.12998/wjcc.v11.i23.5455
Peer-review started: June 6, 2023
First decision: June 21, 2023
Revised: June 26, 2023
Accepted: July 14, 2023
Article in press: July 14, 2023
Published online: August 16, 2023
Cerebral hemorrhage is a common and serious complication of hypertension affecting middle-aged and elderly men. General anesthesia can easily induce complications such as cognitive dysfunction in such patients, which is not conducive to postoperative recovery.
To investigate the correlation between vascular endothelial growth factor (VEGF) and cortisol (Cor) and the prognosis of patients with hypertensive cerebral hemorrhage.
To provide a reference for the prognosis and anesthesia of clinically related operations.
Randomized controlled method and double-blinded method.
Cor and VGEF levels were statistically and significantly higher in patients with poor prognosis than in those with good prognosis (P < 0.05). Multifactor logistic regression analysis revealed that serum Cor and VGEF levels were independent factors influencing hypertensive cerebral hemorrhage.
Cor and VGEF are associated with the occurrence and development of hypertensive cerebral hemorrhage and are significantly associated with neurological impairment and prognosis of patients.
Future studies could focus on exploring the potential mechanisms underlying the correlation between serum Cor and VEGF levels and hypertensive intracerebral hemorrhage. Additionally, more clinical studies are needed to validate the potential of serum Cor and VEGF as biomarkers for predicting patient prognosis and guiding clinical treatment decisions. Finally, further research could aim to investigate potential therapeutic strategies targeting Cor and VEGF to improve patient outcomes.