Copyright
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2023; 11(17): 4035-4059
Published online Jun 16, 2023. doi: 10.12998/wjcc.v11.i17.4035
Published online Jun 16, 2023. doi: 10.12998/wjcc.v11.i17.4035
Acknowledging the use of botanicals to treat diabetic foot ulcer during the 21st century: A systematic review
Illora Narzary, Mrinal Kalita, Banjai Mochahary, Sudem Brahma, Jangila Basumatary, Arvind Kumar Goyal, Department of Biotechnology, Bodoland University, Kokrajhar 783370, Assam, India
Illora Narzary, Department of Zoology, Baosi Banikanta Kakati College, Barpeta 781311, Assam, India
Amit Swarnakar, Medical Unit, Bodoland University, Kokrajhar 783370, Assam, India
Sushil Kumar Middha, Department of Biotechnology, Maharani Lakshmi Ammanni College for Women, Bengaluru 560012, Karnataka, India
Talambedu Usha, Department of Biochemistry, Maharani Lakshmi Ammanni College for Women, Bengaluru 560012, Karnataka, India
Dinesh Babu, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta T6G 2E1, Canada
Author contributions: Goyal AK conceptualized the study; Narzary I, Swarnakar A, Kalita M, Middha SK, Usha T, Mochahary B, Brahma S, Basumatary J, and Goyal AK performed the literature search, analysed the data, created table and wrote the first draft of the manuscript; Babu D, Narzary I, Kalita M, Middha SK and Goyal AK performed the English editing and revision; and all the authors approved the manuscript for final submission.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Arvind Kumar Goyal, PhD, Assistant Professor, Department of Biotechnology, Bodoland University, Debargaon, Kokrajhar 783370, Assam, India.
Received: March 6, 2023
Peer-review started: March 6, 2023
First decision: April 10, 2023
Revised: April 24, 2023
Accepted: May 16, 2023
Article in press: May 16, 2023
Published online: June 16, 2023
Processing time: 98 Days and 5.8 Hours
Peer-review started: March 6, 2023
First decision: April 10, 2023
Revised: April 24, 2023
Accepted: May 16, 2023
Article in press: May 16, 2023
Published online: June 16, 2023
Processing time: 98 Days and 5.8 Hours
Core Tip
Core Tip: Due to the fact that diabetic foot ulcer (DFU) may result in osteomyelitis and lower limb amputation in diabetic patients, this exhaustive systematic review can offer clinically relevant treatments for DFU using natural remedies. This review focuses on metabolites from 19 medicinal plants that could contribute to DFU healing. The recovery time for DFU, the route of administration of medicinal plants, and a comparison of the treated group to the positive and negative control groups were also included in this study to better understand the beneficial effects of using botanicals in the management of DFU.