Retrospective Study
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 26, 2022; 10(9): 2733-2742
Published online Mar 26, 2022. doi: 10.12998/wjcc.v10.i9.2733
Perforating and nonperforating indications in repeated surgeries for Crohn’s disease
Wei-Song Shen, Xiao-Hui Huang, Rui-Qing Liu, Chen-Yang Li, Yi Li, Wei-Ming Zhu
Wei-Song Shen, Department of Gastrointestinal Surgery, Peking University People’s Hospital, Beijing 100044, China
Xiao-Hui Huang, Department of General Surgery, Chinese PLA General Hospital First Medical Center, Beijing 100853, China
Rui-Qing Liu, Department of General Surgery, The affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Chen-Yang Li, Peking University School of Nursing, Peking University School of Nursing, Beijing 100191, China
Yi Li, Wei-Ming Zhu, Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, Jiangsu Province, China
Author contributions: Shen WS, Huang XH, and Liu RQ contributed equally to this work, studied conception and design, and drafting of manuscript; Li CY contributed to acquisition of data; Li Y analysis and interpretation of data; Zhu WM contributed to critical revision.
Supported by Peking University Medicine Fund of Fostering Young Scholars’ Scientific& Technological Innovation Supported by the Fundamental Research Funds for the Central Universities, No. BMU2021PYB009; Peking University People’s Hospital Research and Development Funds, No. RDY2020-14; National Natural Science Foundation of China, No. 82100546.
Institutional review board statement: This study was approved by the Jinling Hospital Ethics Committee. All methods were carried out in accordance with relevant guidelines and regulations.
Informed consent statement: All patients were contacted by telephone and asked to participate in the study. All patients gave informed written consent.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei-Ming Zhu, MD, Chief Doctor, Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, No. 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China. zhuweimingnj@163.com
Received: July 12, 2021
Peer-review started: July 12, 2021
First decision: December 17, 2021
Revised: December 27, 2021
Accepted: February 19, 2022
Article in press: February 19, 2022
Published online: March 26, 2022
Processing time: 253 Days and 2.3 Hours
Core Tip

Core Tip: It was well-known that Crohn’s disease (CD) is a chronic disease characterized by progressive bowel destruction. Our findings suggest that CD becomes more severe and more extensive with the increase in number of surgeries. CD not only has stable characteristics, but also progresses chronically. Perforation is a progressive surgical indication for CD. For CD after operation, anastomosis may be a new classification of disease location.