Published online Mar 26, 2022. doi: 10.12998/wjcc.v10.i9.2733
Peer-review started: July 12, 2021
First decision: December 17, 2021
Revised: December 27, 2021
Accepted: February 19, 2022
Article in press: February 19, 2022
Published online: March 26, 2022
Processing time: 253 Days and 2.3 Hours
It was well-known that Crohn’s disease (CD) is a chronic disease characterized by progressive bowel destruction. Despite advances in medical therapy for CD, most patients with CD require repeated resection surgeries.
To delay postoperative recurrence, it is important to analyze the clinical characteristics and predict postoperative recurrence for surgical patients. Patients with risk factors for earlier postoperative recurrence should be considered for postoperative prophylaxis.
The aim of the current study was to analyze the perforating and nonperforating indications of repeated CD operations and identify the anastomosis characteristics for postoperative CD.
Clinical characteristics of each surgery were collected. Univariate and multivariate analyses were performed to determine risk factors for recurrence.
Even if the correlation of surgical indications between repeated operations, the rate of perforating indication for the second and third surgeries was significantly higher than that of the first surgery. Anastomosis might be a new type of disease location for the classification of postoperative CD.
CD not only has stable characteristics but also progresses chronically. Perforation is a progressive surgical indication for Crohn’s disease. For CD after surgery, anastomosis may be a new classification of disease location.
More study analyze the anastomosis characteristics for postoperative CD and develop new typing standardsfor postoperative CD.