Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2022; 10(8): 2644-2649
Published online Mar 16, 2022. doi: 10.12998/wjcc.v10.i8.2644
Synchronized early gastric cancer occurred in a patient with serrated polyposis syndrome: A case report
Ying-Ze Ning, Guan-Yi Liu, Xiao-Long Rao, Yong-Chen Ma, Long Rong
Ying-Ze Ning, Guan-Yi Liu, Xiao-Long Rao, Yong-Chen Ma, Long Rong, Department of Endoscopy Center, Peking University First Hospital, Beijing 100032, China
Author contributions: Ning YZ wrote the manuscript; Liu GY and Rao XL collected the data; Ma YC analyzed the data; Rong L designed the research study; all authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Long Rong, MD, Chief Doctor, Professor, Department of Endoscopy Center, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100032, China. ronglong8@sina.com
Received: October 25, 2021
Peer-review started: October 25, 2021
First decision: December 17, 2021
Revised: December 28, 2021
Accepted: February 10, 2022
Article in press: February 10, 2022
Published online: March 16, 2022
Processing time: 136 Days and 8.4 Hours
Core Tip

Core Tip: Serrated polyposis syndrome (SPS) is a relatively rare disease. Very little is known regarding the extracolonic cancers associated with SPS. The genetic basis of the process remains unknown. Here, we report a case that presented with SPS and synchronized early gastric cancer. Genetic mutations that were potentially responsible for this condition were sought by exome sequencing.