Li L, Chen HJ, Lian Y, Wang T. Comparison of dental pulp periodontal therapy and conventional simple periodontal therapy as treatment modalities for severe periodontitis. World J Clin Cases 2021; 9(33): 10098-10105 [PMID: 34904079 DOI: 10.12998/wjcc.v9.i33.10098]
Corresponding Author of This Article
Tuo Wang, MHSc, Doctor, Department of Stomatology, The Affiliated Hospital of North Sichuan Medical College, No. 1 Maoyuan South Road, Nanchong 637000, Sichuan Province, China. leeandwill@sina.cn
Research Domain of This Article
Dentistry, Oral Surgery & Medicine
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Nov 26, 2021; 9(33): 10098-10105 Published online Nov 26, 2021. doi: 10.12998/wjcc.v9.i33.10098
Comparison of dental pulp periodontal therapy and conventional simple periodontal therapy as treatment modalities for severe periodontitis
Lu Li, Hong-Jie Chen, Yi Lian, Tuo Wang
Lu Li, Tuo Wang, Department of Stomatology, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Hong-Jie Chen, Department of Stomatology, Wuhou District People's Hospital of Chengdu, Chengdu 610041, Sichuan Province, China
Yi Lian, Department of Stomatology, Chengdu Children Special Hospital, Chengdu 610041, Sichuan Province, China
Author contributions: Wang T designed the research study; Li L performed the research; Chen HJ and Lian Y analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Affiliated Hospital of North Sichuan Medical College Institutional Review Board.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: None.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tuo Wang, MHSc, Doctor, Department of Stomatology, The Affiliated Hospital of North Sichuan Medical College, No. 1 Maoyuan South Road, Nanchong 637000, Sichuan Province, China. leeandwill@sina.cn
Received: July 6, 2021 Peer-review started: July 6, 2021 First decision: July 26, 2021 Revised: July 28, 2021 Accepted: August 20, 2021 Article in press: August 20, 2021 Published online: November 26, 2021 Processing time: 139 Days and 1.4 Hours
ARTICLE HIGHLIGHTS
Research background
Periodontitis is an inflammatory disease of the supporting tissues of the teeth caused by microorganisms, resulting in the progressive destruction of the periodontal ligament.
Research motivation
Periodontitis impacts oral health and quality of life and is an important cause of tooth loss in adults.
Research objectives
We wanted to evaluate the effectiveness of dental pulp periodontal therapy in comparison to simple periodontal therapy for the treatment of severe periodontitis.
Research methods
We selected patients with severe periodontitis at our hospital who met the inclusion and exclusion criteria.
Research results
After treatment, the interleukin-1β (IL-1β) level of the study group was significantly lower than that of the control group, and the IL-10 level was significantly higher than that of the control group.
Research conclusions
Dental pulp periodontal treatment can improve periodontal condition and the overall treatment effect, and reduce the risk of complications to ensure the safety of treatment.
Research perspectives
The level of inflammatory factors reflects the prognosis of periodontitis treatment.
