Published online Apr 6, 2023. doi: 10.12998/wjcc.v11.i10.2246
Peer-review started: January 20, 2023
First decision: February 10, 2023
Revised: February 28, 2023
Accepted: March 3, 2023
Article in press: March 3, 2023
Published online: April 6, 2023
Processing time: 69 Days and 7 Hours
Coronary artery stenosis (CAS) is a common term for the buildup of plaque in the heart’s arteries that could lead to a heart attack. However, the relationship between various cardiac function indicators and CAS is rarely studied.
CAS is one of the major cardiovascular diseases affecting humans worldwide. This disease has been shown to be the leading cause of death in both developed and developing countries. Exploring the correlation between cardiac function indicators and CAS will benefit the patients.
The purpose of our study was to analyze the correlation between the left ventricular ejection fraction (LVEF), left ventricular strain (LVS), and coronary stenosis.
The control group comprised 93 healthy individuals, while the observation group comprised 97 patients with coronary artery disease who were hospitalized between July 2020 and September 2021. Coronary artery disease was assessed using the Gensini score, and LVEF and LVS were measured using magnetic resonance imaging. The interaction between LVEF and LVS was investigated using a linear regression model, while the relationship between LVEF and CAS was examined using Spearman’s correlation.
The LVEF of the observation group was lower than that of the control group. The left ventricular end-systolic volume (LVESV) and left ventricular end-diastolic volume (LVEDV) of the observation group were significantly higher than those of the control group. The longitudinal strain (LS) and circumferential strain (CS) of the observation group were significantly higher than those of the control group; however, the radial strain (RS) of the observation group was lower than that of the control group. LVS, LS, and CS were significantly negatively correlated with the LVEF, while RS was positively correlated with the LVEF. There were significant differences in the LVEF, LVESV, and LVEDV of patients with different Gensini scores. The LVEF significantly decreased and the LVESV and LVEDV increased with increasing Gensini scores. In the observation group, the LVEF was negatively correlated and the LVESV and LVEDV were positively correlated with coronary stenosis.
The LVEF showed a significant linear correlation with LVS and negative correlation with coronary stenosis.
This study did not follow patients over time and did not include patients from other institutions. Therefore, further exploration and research are necessary.