Clinicopathological significance of human leukocyte antigen F-associated transcript 10 expression in colorectal cancer

Table 1 Expression of human leukocyte antigen F-associated transcript 10 in colorectal cancer, n (%)

Group	Staining score	P value	FAT10		P value
			Negative	Positive
			(IS < 4)	(IS ≥ 4)
Normal	0.18 ± 0.72	0.000	60/61 (98.36)	1/61 (1.64)	0.000
Para-cancer	0.64 ± 1.46		55/61 (90.16)	6/61 (9.84)
Cancer	4.46 ± 2.97		22/61 (36.07)	39/61 (63.93)

IS: Immunoreactive score; FAT10: Human leukocyte antigen F-associated transcript 10.

Table 2 Relationship between human leukocyte antigen F-associated transcript 10 expression and clinicopathologic parameters of colorectal cancer

Clinicopathologic parameter	n	+	-	P value
Age, yr				0.095
< 50	8	3	5
≥ 50	53	36	17
Gender				0.476
Male	38	23	15
Female	23	16	7
Tumor size, mm				0.231
< 50	41	28	13
≥ 50	20	11	9
Tumor differentiation				0.325
High	46	31	15
Low	15	8	7
Clinical stage				0.000
I/II	22	7	15
III/IV	39	32	7
Lymph node metastasis				0.000
No	23	8	15
Yes	38	31	7

Table 3 Correlation between human leukocyte antigen F-associated transcript 10 and p53 expression in colorectal cancer

	FAT10 positive	FAT10 negative
p53 positive	30	4
p53 negative	9	18

r = 0.568, P = 0.000. FAT10: Human leukocyte antigen F-associated transcript 10.