Retrospective Study
Copyright ©The Author(s) 2021.
World J Clin Cases. Mar 6, 2021; 9(7): 1580-1591
Published online Mar 6, 2021. doi: 10.12998/wjcc.v9.i7.1580
Table 1 Baseline patient characteristics and short-term treatment responses
Number of patientsTotal patientsDisease progressionDeaths
48
31 (64.5%)
10 (20.8%)
Sex
Male44286
Female434
Age (years): 58 (37-89)
< 5823123
≥ 5825197
Tumour size (cm): 3.2 (1.2-6.6)
< 21120
≥ 2 and < 526212
≥ 51188
Tumour adjacent to the aorta, diaphragm, or digestive tract
Yes652
No42268
Barcelona Clinic Liver Cancer stage
A1882
B30238
C0--
D0--
Child-Pugh score
A483110
B0--
C0--
mRECIST–Post-RFA
CR38 (79.2%)226
PR10 (20.8%)94
SD0--
PD0--
mRECIST–final follow-up
CR16 (33.3%)--
PR1 (2.1%)--
SD0--
PD31 (64.6%)3110
Table 2 Univariate Cox regression analysis of factors related to overall survival
Variable
P value
Sex0.019
Age0.676
Tumour size
< 2 cm0.008
≥ 5 cm0.853
Tumour adjacent to the aorta, diaphragm, or digestive tract0.662
Barcelona Clinic Liver Cancer stage0.157
mRECIST–Post-RFA0.090
Table 3 Prognostic factors and predictors of disease progression according to Cox regression analysis
VariablemTTP (mo)Univariate analysis
Cox proportional hazards model (multivariate analysis)

P value
HR
P value
95%CI
Sex0.246
Male12.9
Female6.0
Age (years)0.0011.0520.0361.003-1.103
< 5835.2
≥ 5811.1
Tumour size (cm)
< 2-< 0.001
≥ 59.70.468
Tumour adjacent to the aorta, diaphragm, or digestive tract0.189
Yes13.9
No9.7
Barcelona Clinic Liver Cancer stage0.010
A35.2
B11.1
mRECIST–Post-RFA0.0034.0800.0211.231-13.524
CR14.1
PR6.4