Timing of convalescent plasma therapy-tips from curing a 100-year-old COVID-19 patient using convalescent plasma treatment: A case report

Table 1 Laboratory findings of patient infected with severe acute respiratory syndrome coronavirus 2 on admission to hospital

Hospital day	Reference range	Day 2	Day 3	Day 4	Day 5	Day 6	Day 7	Day 8	Day 9	Day 10	Day 11	Day 12	Day 13
		Feb 25, 2020	Feb 26, 2020	Feb 27, 2020	Feb 28, 2020	Feb 29, 2020	Mar 1, 2020	Mar 2, 2020	Mar 3, 2020	Mar 4, 2020	Mar 5, 2020	Mar 6, 2020	Mar 7, 2020
Nucleic acid testing					P				P	P		N	N
Antibody						IgG+			IgG+	Detection IgM+	-	IgM+
IL6 in pg/mL	0-10	-			24.63↑				66.21↑	21.47↑	-
BNP in pg/mL	0-100		78.8		135.4↑							242.1↑
Albumin in g/L	35-52	29.4		29.1			33.4	35	31.6			34.7	35.7
Blood clean	1-2.4	0.95↓		0.8↓			0.95	0.91	0.93			1.05	1.08
Globulin, A/GGlutamic pyruvic	0-55	49.3		34.2			17.4	20.7	16.4			13.7	17.3
Transaminase, ALT in U/L, GGT in U/L	12-64	96↑		75↑			57	52	42			35	34
TBA in μmol/L	0-9.67	4		2.5			19.3	14.5	29.7			42.8	11.2
CRE in μmol/L	64-104	73.1		62↓			50.8↓	55.1↓	53.2↓			42.6↓	48.4
UA in μmol/L	210-420	293		346			246	256	241			118↓	116
hs-cTn in pg/mL	0-34.2					19
MYO in ng/mL	0-106					498.7↑
CK-MB in ng/mL	0-3.1					11.1 ↑
D-Dimer in mg/L	0-0.55								3.17				4.38
LYM, %	20-50						12.1↓		14.9↓			12.8↓	14.4
LYM, × 109/L	1.1-3.2						0.63↓		0.69↓			0.84↓	1.08
RBC, × 1012/L	4.3-5.8						3.29↓		3.35↓			3.27↓	3.22
HGB in g/L	130-175						100↓		100↓			97↓	95
Red blood cell specific volume, HCT, %	40-50						29.3↓		29.7↓			29.3↓	28.7
hs-CRP in mg/L	0-10	108.43↑					49.18↑					27.03	24.97
tHb in g/L	117-174			70↓					94↓				115
Carbon monoxide	0.5-1.5			2.2↑					1.3				1.5
COHb, % un-ionized HHb, %	0--5			-0.4					0.6				0.2
Glucose in mmol/L	3.6-5.2			10.9↑					6.2↑				8.1
Base excess of blood in mmol/L	-2-3			-5.1↓					4.6↑				4.1
Beecf in mmol/L	-2-3			-5.6↓					5↑				4.7

-: Negative; +: Positive; ALT: Alanine aminotransferase; Beecf: Base excess of the extracellular fluid; CK-MB: Creatine kinase isoenzyme-MB; COHb: Hemoglobin; CRE: Creatinine; GGT: γ-Glutamyl transferase; HCT: Hematocrit; HGB: Hemoglobin; HHb: Hemoglobin; hs-CRP: Hypersensitive C-reactive protein; hs-cTn: High-sensitivity cardiac troponin; Ig: Immunoglobulin; IL6: Interleukin-6; LYM: Lymphocyte absolute value; MYO: Myoglobin; N: Negative; P: Positive; RBC: Red cell count; TBA: Total bile acid; tHb: Total hemoglobin; UA: Uric acid.