Mediastinal lymphadenopathy in COVID-19: A review of literature

Table 1 Summarization of included articles

Ref.	Country	Type of article	n	Age (yr)	Male (%)	Findings	n (%) of ML
Valette et al[29]	France	R	9	NA	NA	GGO, reticulation, or consolidation (100%)	6 (66)
Peng et al[20]	China	R	201	Median (range); 6 (3 h-15 yr)	118 (58.7)	GGO (69.7%), consolidation (37%)	0 (0)
Bayramoglu et al[21]	Turkey	R	37	Median (IQR); M 12.5 (8-15.5); F 15 (10-16)	18 (48.6)	GGO with/without consolidation (45.9%)	3 (8.1)
Grassi et al[24]	Italy	R	134	Mean (range); 69.3 (29-93)	89 (71)	GGO and consolidation (71%), crazy-paving pattern (75%)	69 (54.8)
Pakdemirli et al[30]	United Kingdom	R	18	mean (SD); 53.3 (NA)	9 (50)	GGO (44%), pleural thickening (50%), focal vascular engorgement (83%), B/L lesion (100%)	3 (17)
Li et al[31]	China	R	19	Mean (range); 63 (25-80)	11 (57.9)	GGO (100%), consolidation (73.7%), interlobular septal thickening (63.2%)	0
Gong et al[22]	China	R	10	Mean (range); 30 (26-40)	0 (0)	GGO (100%), B/L lesion (80%)	0
Sardanelli et al[25]	Italy	R	410	Median (IQR); 68 (57-78)	288 (70)	NA	76 (19)
Luo et al[32]	China	R	70	NA	NA	GGO (39%), GGO and consolidation (59%), B/L lesion (84%)	2 (2.8)
Huang et al[33]	China	C	7	Median (range); 56 (49-64)	3 (42.9)	GGO (100%)	0 (0)
Guan et al[34]	China	R	54	mean (SD); 44.8 (16.7)	25 (46)	GGO (100%), crazy-paving pattern (90%), B/L lesion (82%)	0 (0)
Doroudinia et al[35]	Iran	C	1	56	0 (0)	GGO both lungs	0 (0)
Lu et al[36]	China	C	9	mean (SD); 7.8 (5.3)	5 (55.6)	GGO (44.4%)	0 (0)
Lei et al[37]	China	R	14	mean (SD); 47 (19)	8 (57.1)	GGO (90%), irregular linear (90%), consolidation (90%)	0 (0)
Himoto et al[38]	Japan	R	6	Median (range); 58.5 (45-81)	5 (83.3)	B/L lesion (100%), GGO without consolidation (66.7%)	0 (0)
Guan et al[39]	China	R	53	Mean (range); 42 (1-86)	25 (47)	GGO (100%), crazy-paving pattern (89%), B/L lesion (79%)	0 (0)
Zhao et al[23]	China	R	80	mean (SD); 44 (11.7)	43 (54)	GGO (71%), B/L lesions (95%), subpleural lesion (90%)	1 (1.3)
Albarello et al[19]	China	C	2	66 and 67	1 (50%)	GGO and ML were found in both cases	NA
Chung et al[40]	China	R	21	mean (SD); 51(14)	13 (62)	GGO (57%), multi-lobar lesion (71%), B/L lesion (76%)	0 (0)

B/L: Bilateral; C: Case report/series; F: Female; GGO: Ground-glass opacities; IQR: Interquartile range; M: Male; ML: Mediastinal lymphadenopathy; n: Number of coronavirus disease 2019 case with chest imaging; NA: Not applicable; R: Retrospective review; SD: Standard deviation.