Healthy neonate born to a SARS-CoV-2 infected woman: A case report and review of literature

Table 1 The patient’s clinical laboratory examination results on January 30

Measure	Reference range	Patient
White blood cell count (per microliter)	4000-10000	8130
Absolute lymphocyte count (per microliter)	800-4500	510
Proportion of neutrophils (%)	50.0-70.0	90.7
Proportion of lymphocytes (%)	20.0-45.0	6.3
Random glucose (mmol/L)	4.40-6.70	11.55
Triglyceride (mmol/L)	0.60-1.70	2.73
Fibrinogen concentration (g/L)	2.00-4.00	6.24
Activated partial thromboplastin time (s)	28.0-43.5	46.0
Procalcitonin (ng/mL)	0-0.5	0.5
C reactive protein (mg/L)	0-5.0	80.2
Alkaline phosphatase (U/L)	30-162	113
Alanine aminotransferase (U/L)	0-55	30
D-dimer (mg/liter)	0-0.5	1.2
Analysis of blood gas
PCO2	35.0-45.0	27.1
pH	7.35-7.45	7.41
PO2	80.0-100.0	91.2
BE	± 3	-6
Toxoplasma antibody IgG		Positive
Mycoplasma pneumoniae antibody IgG (AU/mL)	0-36.0	86.6
Rubella antibody IgG		Positive
Toxoplasma antibody IgG		Positive

Table 2 Summary of reports on pregnancies associated with severe acute respiratory syndrome infection

Ref.	SS	Nationality	GAAI (wk)	ICUA	Maternal comorbid conditions	Maternal outcome	Fetal outcome	Delivery details	Journal
Wong et al[14], 2004	12	Hong Kong	First trimester 7; Second trimester 3; Third trimester 2	Unknown	Oligohydramnios and fetal growth restriction 2	Died 3; Survived 9	Survived 5; Ongoing pregnancy 2	Spontaneous miscarriage 4; Induced labor 2; Preterm 4; Ongoing 2	American J Obstet Gynecol
Shek et al[15], 2003	5	Hong Kong	Unknown	Yes 4; Unknown 1	Unknown	Died 2; Survived 2; Unknown 1	Survived 5	Preterm 4; Term 1	Pediatrics
Robertson et al[16], 2004	1	United States	Second trimester	Yes	Gestational diabetes	Survived	Survived	Term	Emerg Infect Dis
Stockman et al[17], 2004	1	United States	First trimester	No	Premature rupture of membranes	Survived	Survived	Delivery at 36 wks gestation	Emerg Infect Dis
Yudin et al[18], 2005	1	Canada	Third trimester	No	No	Survived	Survived	Term	Obstet. Gynecol
Wang et al[19], 2004	6	China	Second trimester 2; Third trimester 4	Unknown	Premature rupture of membranes 1; Nephrotic syndrome	Survived 6	Survived 7; Died 1	Preterm 3; Term 4	Chin J Perinat Med

SS: Sample size; GAAI: Gestational age at infection; ICUA: Intensive care unit admission.

Table 3 Summary of pregnancies associated with Middle East respiratory syndrome infection

Ref.	SS	Nationality	GAAI (wk)	ICUA	Maternal comorbid conditions	Maternal outcome	Fetal outcome	Delivery details	Journal
Memish et al[21], 2019	2	Saudi	First trimester 1; Second trimester 1	No	Hypertension 1	Survived	Survived 2	Term 2	J Microbiol, Immunol Infect
Assiri et al[22], 2016	5	Saudi	Second trimester 3; Third trimester 2	Yes 5	Preeclampsia 1; Asthma pulmonary fibrosis 1	Survived 3; Died 2	Died 2; Survived 3	Intrauterine fetal death at 34 wk 1; Preterm 1; Term 3	Clin Infect Dis
Payne et al[23], 2015	1	Jordanian	Second trimester	No	None	Survived	Still birth	Still birth at 5 mo	J Infect Dis
Malik et al[24], 2016	1	United Arab Emirates	Third trimester	Yes	None	Died	Survived	Caesarean section at 32 wk	Emerg Infect Dis
Jeong et al[25], 2017	1	South Korean	Third trimester	No	Gestational diabetes	Survived	Survived	Term	J Korean Med Sci
Alserehi et al[26], 2016	1	Saudi	Third trimester	Yes	Hypothyroidism	Survived	Survived	Caesarean section at 32 wk	BMC Infect Dis

Note: SS: Sample size; GAAI: Gestational age at infection; ICUA: Intensive care unit admission.