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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Healthy neonate born to a SARS-CoV-2 infected woman: A case report and review of literature
Rong-Yue Wang, Ke-Qiong Zheng, Bo-Zhong Xu, Wei Zhang, Jin-Ge Si, Chong-Yong Xu, Hua Chen, Zhang-Ye Xu, Xin-Mei Wu
Rong-Yue Wang, Hua Chen, Zhang-Ye Xu, Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China
Ke-Qiong Zheng, Bo-Zhong Xu, Wei Zhang, Department of Obstetrics and Gynecology, The Yueqing People’s Hospital, Wenzhou 325600, Zhejiang Province, China
Jin-Ge Si, Department of Obstetrics and Gynecology, The Zhongshan Affiliated Hospital of Sun Yat-Sen University, Zhongshan 528400, Guangdong Province, China
Chong-Yong Xu, Department of Radiology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China
Xin-Mei Wu, Department of Clinical Laboratory, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China
Author contributions: Wang RY, Zheng KQ, Xu BZ, and Wu XM made substantial contributions to the study ideas and design; Wu XM was responsible for the manuscript; Wang RY, Zheng KQ, Xu BZ, Zhang W, and Xu CY collected samples and confirmed data accuracy; Wang RY and Chen H participated in drafting the manuscript; Wang RY, Si JG, Xu ZY, and Wu XM made substantial revisions to the manuscript; all of the authors read and approved the final manuscript.
Supported by the Zhejiang Provincial Natural Science Foundations, No. LY19H040006 and LQ15H040006.
Informed consent statement: Written consent for publication was acquired from the patient, and the signed consent will be provided upon request.
Conflict-of-interest statement: The authors report no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
http://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Xin-Mei Wu, MSc, Technician, Department of Clinical Laboratory, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, No. 109 West Xueyuan Road, Wenzhou 325027, Zhejiang Province, China.
applewuxinmei@126.com
Received: May 12, 2020
Peer-review started: May 12, 2020
First decision: September 14, 2020
Revised: September 22, 2020
Accepted: October 12, 2020
Article in press: October 12, 2020
Published online: December 6, 2020
Processing time: 206 Days and 1.1 Hours
BACKGROUND
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly discovered coronavirus that has generated a worldwide outbreak of infections. Many people with coronavirus disease-2019 (COVID-19) have developed severe illness, and a significant number have died. However, little is known regarding infection by the novel virus in pregnant women. We herein present a case of COVID-19 confirmed in a woman delivering a neonate who was negative for SARS-CoV-2 and related it to a review of the literature on pregnant women and human coronavirus infections.
CASE SUMMARY
The patient was a 36-year-old pregnant woman in her third trimester who had developed progressive clinical symptoms when she was confirmed as infected with SARS-CoV-2. Given the potential risks for both the pregnant woman and the fetus, an emergency cesarean section was performed, and the baby and his mother were separately quarantined and cared for. As a result, the baby currently shows no signs of SARS-CoV-2 infection (his lower respiratory tract samples were negative for the virus), while the mother completely recovered from COVID-19.
CONCLUSION
Although we presented a single case, the successful result is of great significance for pregnant women with SARS-CoV-2 infection and with respect to fully understanding novel coronavirus pneumonia.
Core Tip: We achieved successful outcomes for both the severe acute respiratory syndrome coronavirus 2 infected mother and the neonate. Even though this is a single successful case, the identification, diagnosis, clinical course, and management are of significance for understanding the clinical manifestation, transmission, and related risks among special populations due to the ongoing outbreak of coronavirus disease-2019 pneumonia.
