Diffuse invasive signet ring cell carcinoma in total colorectum caused by ulcerative colitis: A case report and review of literature

Table 1 Mutations of gene detection results

Mutant gene	Abundance (%)	Exon	cDNA	Protein	Type
MTOR	0.61	47	c.6617A>G	p.N2206S	Non-synonymous
HRAS	0.85	2	c.81T>C	p.H27H	Synonymous
SLCO1B1	0.79	6	c.597C>T	p.F199F	Synonymous
AKT1	0.57	3	c.103T>C	p.F35L	Non-synonymous
TP53	0.5	8	c.840A>G	p.R280R	Synonymous
STK11	0.51	4	c.524A>T	p.K175M	Non-synonymous
	0.51	4	c.530T>C	p.I177T	Non-synonymous
XRCC1	0.66	10	c.1196A>G	p.Q399R	Non-synonymous
VHL	13.95	2	c.T355C	p.F119L	Non-synonymous
XRCC1	10.34	6	c.C580T	p.R194W	Non-synonymous

Table 2 Mutations of gene detection results

Gene	Mutation detection results
KRAS	Wild
NRAS	Wild
BRAF	Wild
NTRK	Not detected
BAT25	Not detected
BAT26	Not detected
NR21	Not detected
NR24	Not detected
NR27	Not detected