Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Feb 16, 2022; 10(5): 1729-1737
Published online Feb 16, 2022. doi: 10.12998/wjcc.v10.i5.1729
Diffuse invasive signet ring cell carcinoma in total colorectum caused by ulcerative colitis: A case report and review of literature
Zhi Zhang, Peng-Fei Yu, Guo-Li Gu, Yu-Hui Zhang, Yu-Ming Wang, Zhi-Wei Dong, Hai-Rui Yang
Zhi Zhang, Peng-Fei Yu, Guo-Li Gu, Yu-Hui Zhang, Zhi-Wei Dong, Hai-Rui Yang, Department of General Surgery, Air Force Medical Center, Chinese People's Liberation Army, Beijing 100142, China
Yu-Hui Zhang, Graduate School, Hebei North University, Zhangjiakou 075000, Hebei Province, China
Yu-Ming Wang, Health Team, 93656 Troop of Chinese People's Liberation Army, Beijing 101113, China
Author contributions: Gu GL, Zhang Z and Yu PF contributed equally to this study; Gu GL designed the research; Zhang Z, Yu PF, Wang YM, Zhang YH, Dong ZW and Yang HR collected and analyzed the clinical data; Gu GL and Zhang Z wrote the manuscript; Gu GL revised the manuscript; all authors issued final approval for the version to be submitted.
Supported by Beijing Capital Medical Development Research Fund, No. Shoufa2020-2-5122.
Informed consent statement: The study participants and their legal guardian provided informed written consent prior to study enrollment.
Conflict-of-interest statement: We state that there is no financial or other relationship that might be perceived as leading to a conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Guo-Li Gu, FRCS (Gen Surg), Chief Doctor, Department of General Surgery, Air Force Medical Center, Chinese People's Liberation Army, No. 30 Fucheng Road, Haidian District, Beijing 100142, China. kzggl@163.com
Received: October 15, 2021
Peer-review started: October 15, 2021
First decision: December 1, 2021
Revised: December 5, 2021
Accepted: December 28, 2021
Article in press: December 28, 2021
Published online: February 16, 2022
Processing time: 118 Days and 20 Hours
Core Tip

Core tip: Primary signet-ring cell carcinoma (SRCC) of the colorectum is extremely rare clinically. This type of colorectal cancer has certain clinical, pathological and biological characteristics that are different from ordinary colorectal cancer. We report a rare case of ulcerative colitis leading to diffuse infiltrating SRCC of the colorectum, and review the relevant literature studying the disease.