Atypical imaging features of the primary spinal cord glioblastoma: A case report

Table 1 Review of the literature on primary spinal cord glioblastoma with qualified magnetic resonance images

Case No.	Ref.	Age/sex	Symptoms	Lesion location	Intramedullary only	Imaging findings	Surgery/therapy	Survival in month
1	Ferrante et al[3], 2021	34 yr/F	MW, SD	Nearly entire cervical spinal cord and medulla oblongata	Yes	Isointense to hypointense on T1WI, isointense to hyperintense on T2WI, homogeneous enhancement	None	NR
		64 yr/M	MW, SD	Conus medullaris	Yes	Hyperintense on T2WI, peripheral enhancement, necrosis enhancing nodule	STR, radio/chemotherapy	33
		47 yr/M	Paresthesia, pain, MW, SD	Cervical and thoracic	Yes	Multifocal lesion (C5-C7) and (T3-T5), peripheral enhancement, necrotic center	Biopsy, radio/chemotherapy	10
2	Shen et al[4], 2020	47 yr/F	Paresthesia, paralysis	T12	Yes	T12 nodular, isointense to hyperintense on T2WI, central significant enhancement	surgical resection, NR	NR
3	Delgado et al[5], 2019	21 yr/F	Pain, weakness, paresthesia	T10-T12, L1	Yes	60 mm expansile mass, T10-T12 down to L1, nodular significant enhancement	NTR, radio/chemotherapy	Recurrence in 4 mo
4	Chanchotisatien et al[6], 2019	27 yr/F	Dysuria, numbness, weakness, back Pain	T4-T12, T5-T12, respectively	No	Homogenous, hyperintense T2WI, intra-/extramedullary regions from T4-T12 and T5-T12, respectively, homogenous enhancement	Biopsy, radio/chemotherapy	NR
5	Caro-Osorio et al[7], 2018	48 yr/F	Numbness, pain	C1-C3	Yes	Hypointense on T1WI, hyperintense on T2WI, heterogeneous enhancement	STR, radio/chemotherapy	8
6	Shen et al[1], 2017	15 yr/F	Numbness, weakness	C4-C7	Yes	Hyperintense on T2WI, inhomogeneous enhancement	NTR, radio/chemotherapy	13
7	Nunn et al[12], 2017	31 yr/M	MW, SD	T9-T2	Yes	Hyperintense on T2WI, spinal cord expanding, heterogeneous enhancement	Surgical resection, radio/chemotherapy	14
8	Prasad et al[13], 2012	15 yr/F	Paraparesis, dysesthesia, urinary incontinence, SD	C6-T7	Yes	Enlargement of cord, heterogeneously enhancing	STR, radio/chemotherapy	6
		35 yr/M	Pain, paraplegia, urinary incontinence, SD	T11-L1	Yes	Enlargement of cord, heterogeneously enhancing	NTR, radio/chemotherapy	15

F: Female; M: Male; MW: Motor weakness; NR: No relief; NTR: Near total resection; SD: Sensory disturbances; STR: Subtotal resection; WI: Weighted imaging.