Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2022; 10(22): 7950-7959
Published online Aug 6, 2022. doi: 10.12998/wjcc.v10.i22.7950
Atypical imaging features of the primary spinal cord glioblastoma: A case report
Xin-Yu Liang, Yao-Ping Chen, Qiao Li, Ze-Wang Zhou
Xin-Yu Liang, Ze-Wang Zhou, Department of Radiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China
Yao-Ping Chen, Department of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China
Qiao Li, Department of Endocrinology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China
Author contributions: Liang XY contributed to literature retrieval and screening, data reduction, and drafting of the manuscript; Chen YP contributed to literature retrieval and screening, and data analysis; Li Q contributed to acquisition of data and images, and data analysis; Zhou ZW contributed to study design and revising the manuscript critically for important intellectual content.
Supported by the “Excellent Doctoral Dissertation Incubation Grant of First Clinical School of Guangzhou University of Chinese Medicine”, No. YB201903.
Informed consent statement: The obtained informed consent is presented in the supplementary materials for the case report to be published.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
Corresponding author: Ze-Wang Zhou, MM, Doctor, Department of Radiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 12 Airport Road, Guangzhou 510405, Guangdong Province, China. zhouzewang666@163.com
Received: December 13, 2021
Peer-review started: December 13, 2021
First decision: April 8, 2022
Revised: April 29, 2022
Accepted: June 23, 2022
Article in press: June 23, 2022
Published online: August 6, 2022
Processing time: 221 Days and 3.1 Hours
Core Tip

Core Tip: This is the first literature review to summarize the imaging features of surgical and pathologically confirmed glioblastoma in the spinal cord. Lesions reported in previous cases were located in the spinal canal exclusively. Intramedullary glioma that extended beyond the spinal canal has not been reported before. In this case, the tumor grew across and beyond the spinal canal and appeared benign, which led to the misdiagnosis of neurogenic tumors. A definitive diagnosis requires histopathological confirmation. However, complete recognition of the imaging signs of the disease may facilitate early accurate diagnosis.