Relationship between Ki-67 and CD44 expression and microvascular formation in gastric stromal tumor tissues

Table 1 Relationship between the expression of different Ki-67 proteins and characteristics of gastric stromal tumors, n (%)

Index	Ki-67 Protein positive (n = 54)	Ki-67 Protein negative (n =32)	χ2	P value
Age (yr)			1.173	0.279
≥ 60	29 (53.70)	21 (65.63)
< 60	25 (46.30)	11 (34.38)
Gender			0.844	0.358
Male	24 (44.44)	11 (34.38)
Female	30 (55.56)	21 (65.63)
Lesion site			1.250	0.535
Gastric antrum	7 (12.96)	5 (15.63)
Body of stomach	14 (25.93)	5 (15.63)
Base of stomach	33 (61.11)	22 (68.75)
Risk classification			7.380	0.025
Very low risk	15 (27.78)	17 (53.13)
Low risk	26 (48.15)	13 (40.63)
Medium and high risk	13 (24.07)	2 (6.25)
Mitosis			5.156	0.023
≤ 5	33 (61.11)	27 (84.38)
> 5	21 (38.89)	5 (15.63)
Lesion diameter (cm)			1.764	0.184
> 2.0 cm	38 (70.37)	18 (56.25)
≤ 2.0 cm	16 (29.63)	14 (43.75)

Table 2 Relationship between the expression of different CD44 proteins and characteristics of gastric stromal tumors, n (%)

Index	CD44 protein positive (n = 59)	CD44 protein negative (n = 27)	χ2	P value
Age (yr)			1.176	0.278
≥ 60	32 (54.24)	18 (66.67)
< 60	27 (45.76)	9 (33.33)
Gender			0.884	0.347
Male	26 (44.07)	9 (33.33)
Female	33 (55.93)	18 (66.67)
Lesion site			1.283	0.256
Gastric antrum	7 (11.86)	5 (18.52)
Body of stomach	12 (20.34)	7 (25.93)
Base of stomach	40 (67.80)	15 (55.56)
Risk classification			6.534	0.038
Very low risk	18 (30.51)	14 (51.85)
Low risk	27 (45.76)	12 (44.44)
Medium and high risk	14 (23.73)	1 (3.70)
Mitosis			6.822	0.009
≤ 5	36 (61.02)	24 (88.89)
> 5	23 (38.98)	3 (11.11)
Lesion diameter (cm)			1.584	0.208
> 2.0 cm	41 (69.49)	15 (55.56)
≤ 2.0 cm	18 (30.51)	12 (44.44)

Table 3 Comparison of microvessel density in gastric stromal tumor tissues with different expression of Ki-67 and CD 44 protein (mean ± SD)

	n	MVD (/Hp)	t	P value
Ki-67 expression			0.889	0.377
Positive	54	15.41 ± 3.10
Negative	32	14.82 ± 2.75
CD44 expression			3.003	0.004
Positive	59	15.92 ± 2.94
Negative	27	13.86 ± 2.98

MVD: Microvessel density.