FGFR2-TSC22D1, a novel FGFR2 fusion gene identified in a patient with colorectal cancer: A case report

Figure 1 Pathological detection. A: Hematoxylin and eosin staining; B: Abdominal computed tomography showed a tumor lesion in the ascending colon.

Figure 2 Next-generation sequencing and droplet digital polymerase chain reaction findings for the primary tissue sample. A: A novel intergenic region between FGFR2 exons 1-17 and TSC22D1 exon 3 was identified; B: Next-generation sequencing results showing the breakpoint of the FGFR2-TSC22D1 fusion; C: Droplet digital polymerase chain reaction (ddPCR) amplification charts. Ch1 is FAM Channel (mutant type) and Ch2 is VIC channel (wild type). In these charts, black points represent PCR negative droplets, and blue and green points represent PCR positive droplets in FAM channel and VIC channel, respectively.