Histopathological classification and follow-up analysis of chronic atrophic gastritis

Figure 1 Histological analysis. A: Simple type chronic atrophic gastritis—only thinning mucosal and gland atrophy, no glandular hyperplasia or heterotypic and intestinal metaplasia. Magnification, 20 ×; B: Hyperplasia type chronic atrophic gastritis—inherent layer atrophy accompanied by glandular hyperplasia, mainly quantitative, with no epithelial atypical hyperplasia. Magnification, 20 ×; C: Intestinal metaplasia type chronic atrophic gastritis—intrinsic glandular atrophy accompanied by intestinal metaplasia, mainly small intestinal epithelial metaplasia. Magnification, 20 ×; D: Intraepithelial neoplasia type chronic atrophic gastritis—inherent layer atrophy with high grade intraepithelial neoplasia. Magnification, 20 ×.

Figure 2 Histopathological typing and follow-up time of chronic atrophic gastritis. CAG: Chronic atrophic gastritis; ESD: Endoscopic submucosal dissection.