Cronkhite-Canada syndrome with steroid dependency: A case report

Figure 1 Physical examination findings included alopecia, brown macular pigmentation over the facial region, palms and soles, and onychodystrophy of the fingernails and toenails. A: Facial region; B: Palms; C: Soles.

Figure 2 Gastroscopy. A: Gastroscopy revealed multiple polyps in the stomach; B: Endoscopic ultrasonography revealed diffuse thickening of the gastric mucosa of up to 8.5 mm in thickness; C: Colonoscopy revealed numerous polyps occupying the colonic and rectal mucosa.

Figure 3 Examination after treatment. A: The patient showed great improvement in his skin pigmentation after 6-8 mo of steroid therapy; B: The patient showed great improvement in his nail dystrophy after 6-8 mo of steroid therapy; C and D: After 14 mo of treatment, gastroscopy revealed several polyps with a diameter of 3-4 mm in the gastric antrum (C), and colonoscopy revealed polyp regression (D).