Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2021; 9(14): 3466-3471
Published online May 16, 2021. doi: 10.12998/wjcc.v9.i14.3466
Cronkhite-Canada syndrome with steroid dependency: A case report
Dan Jiang, Guo-Du Tang, Ming-Yu Lai, Zhen-Ning Huang, Zhi-Hai Liang
Dan Jiang, Guo-Du Tang, Ming-Yu Lai, Zhen-Ning Huang, Zhi-Hai Liang, Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Author contributions: Jiang D collected basic patient information and imaging data and wrote the main content of the manuscript; Tang GD reviewed the literature and made the diagnosis; Lai MY and Huang ZN were responsible for the analysis and interpretation of data; Liang ZH was responsible for the conception and design of the study and the final approval of the version of the article to be published; All authors have read and approve the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zhi-Hai Liang, MD, Professor, Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China. lzh@stu.gxmu.edu.cn
Received: December 15, 2020
Peer-review started: December 15, 2020
First decision: January 17, 2021
Revised: January 27, 2021
Accepted: March 15, 2021
Article in press: March 15, 2021
Published online: May 16, 2021
Processing time: 135 Days and 5.1 Hours
Core Tip

Core Tip: Cronkhite-Canada syndrome (CCS) is a rare gastrointestinal polyposis syndrome. Here, we report a case of CCS that has been followed for almost 4 years. The patient was treated with prednisone. After he discontinued prednisone, his clinical and endoscopic manifestations relapsed. The patient was given prednisone again, and it was effective in bringing about a second remission. It is necessary to extend the duration of prednisone maintenance therapy for CCS. Surveillance endoscopy at intervals of 1 year or less is recommended to assess mucosal disease activity.