Value of glucose transport protein 1 expression in detecting lymph node metastasis in patients with colorectal cancer

Figure 1 Immunohistochemical staining for glucose transport protein 1 in colorectal cancer. Glucose transport protein 1 expression was demonstrated as cytoplasmic or membranous staining. A-D: The score was assessed according to the intensity [0 = negative (A), 1 = weak (B), 2 = moderate (C), 3 = strong (D); × 100]. A score of 2 or higher was considered as positive.

Figure 2 Immunohistochemical staining for glucose transport protein 3, hexokinase-II, and hypoxia-inducible factor-1 in colorectal cancer. Glucose transport protein 3 (GLUT-3) and hexokinase-II expressions were demonstrated as cytoplasmic or membranous staining. A: GLUT-3 negative; B: GLUT-3 positive; C: Hexokinase-II negative; D: Hexokinase-II positive; E and F: Hypoxia-inducible factor-1 (HIF-1) expression was demonstrated as nuclear staining (E: HIF-1 negative, F: HIF-1 positive).