Triple hit to the kidney-dual pathological crescentic glomerulonephritis and diffuse proliferative immune complex-mediated glomerulonephritis: A case report

Figure 1 Light microscopy findings. A: Many glomeruli had active global cellular crescents with segmental necrotizing lesions and polymorphonuclear leukocytes in the glomeruli. Hematoxylin and eosin (H&E), magnification 200 ×; B: Rare glomeruli that were not involved by crescents showed mesangial hypercellularity. H&E, magnification 200 ×.

Figure 2 Immunofluorescence studies. A: No glomerular staining for albumin; B: Bright diffuse global linear staining for immunoglobulin (Ig)G was seen along the glomerular capillary loops; C: Moderate to prominent diffuse global granular staining for IgA was seen in the glomerular mesangium; D: Prominent diffuse global granular staining for C3 was seen in the glomerular mesangium.

Figure 3 Ultrastructural examination. A: Electron dense immune complex type deposits were seen in paramesangium (arrow); B: Electron dense immune complex type deposits were seen in the mesangium (arrow).