Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 16, 2022; 10(32): 11869-11876
Published online Nov 16, 2022. doi: 10.12998/wjcc.v10.i32.11869
Triple hit to the kidney-dual pathological crescentic glomerulonephritis and diffuse proliferative immune complex-mediated glomerulonephritis: A case report
Dalia Ibrahim, Sergey V Brodsky, Anjali A Satoskar, Laura Biederman, Natallia Maroz
Dalia Ibrahim, Sergey V Brodsky, Anjali A Satoskar, Laura Biederman, Department of Pathology, Ohio State University, Columbus, OH 43210, United States
Natallia Maroz, Department of Medicine, Wright State University, Dayton, OH 45409, United States
Author contributions: Ibrahim D wrote a draft of the manuscript and acquired the images; Brodsky SV interpreted the case, reviewed critically drafts and approved the final version; Maroz N wrote the clinical information and treatment parts, contributed to the discussion, and revised the manuscript critically and approved the final version; Satoskar AA and Biederman L reviewed drafts and gave their pathology input and modifications and approved the final version.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sergey V Brodsky, MD, PhD, Academic Research, Department of Pathology, Ohio State University, 333 w 10th Ave Graves Hall B078, Columbus, OH 43210, United States. sergey.brodsky@osumc.edu
Received: May 16, 2022
Peer-review started: May 16, 2022
First decision: June 27, 2022
Revised: July 25, 2022
Accepted: August 21, 2022
Article in press: August 21, 2022
Published online: November 16, 2022
Processing time: 175 Days and 10.2 Hours
Core Tip

Core Tip: Unusual constellation of morphologic findings in the kidney, that include anti-glomerular basement membrane disease, anti-neutrophilic antibody-associated crescentic and necrotizing glomerulonephritis and immune-complex mediated glomerulonephritis with unusual pathogenesis and grave outcome for the patient. Kidney biopsy is warranted in patients with rapidly progressive decline in kidney function and hematuria to reveal the diagnosis, pathogenesis and the optimal treatment course.