Diffuse uterine leiomyomatosis: A case report and review of literature

Figure 1 Pedigree diagram of the family.

Figure 2 Pelvic magnetic resonance imaging T2-weighted images before and after operations. A: Sagittal section before transabdominal myomectomy (TM); B: Coronal section before TM; C: Sagittal section before hysteroscopic myomectomy (HM); D: Coronal section before HM; E: Sagittal section after HM; F: Coronal section after HM.

Figure 3 Pathological features of diffuse uterine leiomyomatosis at 400 × original magnification. A: The lesion displayed typical spindle-shaped smooth muscle cells forming an interlacing fascicular arrangement with ill-defined cell borders, eosinophilic filamentous cytoplasm, cigar-shaped nuclei, and small nucleoli. Mitotic activity was uniformly low (HE staining); B: Immunohistochemistry: Progesterone receptor-positive, 50%-60%; C: Immunohistochemistry: Estrogen receptor-negative; D: Immunohistochemistry: Ki-67-positive, approximately 5%.