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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 26, 2022; 10(24): 8797-8804
Published online Aug 26, 2022. doi: 10.12998/wjcc.v10.i24.8797
Published online Aug 26, 2022. doi: 10.12998/wjcc.v10.i24.8797
Diffuse uterine leiomyomatosis: A case report and review of literature
Hui-Min Ren, Gang-Jie Hong, Department of Gynecology, Zhoushan Branch Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Zhoushan 316000, Zhejiang Province, China
Qing-Zhu Wang, Department of Obstetrics and Gynecology, Ningbo Hangzhou Bay Hospital, Ningbo 315336, Zhejiang Province, China
Jia-Nan Wang, Department of Pathology, Zhoushan Branch Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Zhoushan 316000, Zhejiang Province, China
Shuang Zhou, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200090, China
Jun-Yan Zhu, Shan-Ji Li, Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
Author contributions: Ren HM and Wang QZ contributed equally to this work; all authors contributed to the design and conduct of the study and approved the submission of this work for publication.
Informed consent statement: Informed consent was obtained from the patients for participation in this study and the publication of the results.
Conflict-of-interest statement: None of the authors have any conflicts of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shan-Ji Li, Doctor, MD, Associate Chief Physician, Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiaotong University School of Medicine, No. 160 Pujian Road, Pudong New Area, Shanghai 200127, China. 13524459739@163.com
Received: April 29, 2022
Peer-review started: April 29, 2022
First decision: May 12, 2022
Revised: May 24, 2022
Accepted: July 16, 2022
Article in press: July 16, 2022
Published online: August 26, 2022
Processing time: 108 Days and 16.9 Hours
Peer-review started: April 29, 2022
First decision: May 12, 2022
Revised: May 24, 2022
Accepted: July 16, 2022
Article in press: July 16, 2022
Published online: August 26, 2022
Processing time: 108 Days and 16.9 Hours
Core Tip
Core Tip: Diffuse uterine leiomyomatosis (DUL) is a benign uterine smooth muscle neoplasm with unknown etiology. Hysterectomy is the only curative therapy. We report a 27-year-old female with no sexual activity who was diagnosed with DUL. The patient was misdiagnosed with leiomyoma preoperatively, followed by treatment with transabdominal myomectomy (TM), a gonadotropin-releasing hormone analog, and hysteroscopic myomectomy plus hymen repair. This case highlights the importance of pelvic magnetic resonance imaging as a diagnostic tool. For women who want to preserve fertility, conservative surgery should be an option. When TM is chosen, a modified new myomectomy should be considered to avoid the drawbacks of traditional TM.