Serum-negative Sjogren's syndrome with minimal lesion nephropathy as the initial presentation: A case report

Figure 1 Kidney histological examination. A: Hematoxylin-eosin staining, ×20; B: Hematoxylin-eosin staining, ×20; C: Periodic acid-Schiff stain, ×20; D: Periodic acid-Schiff stain, ×40; B and C: Light microscopic analysis of a kidney biopsy sample showed no abnormalities in the glomeruli and occasional focal aggregation of interstitial inflammatory cells.

Figure 2 Electron microscopic analysis of a kidney biopsy sample revealed diffuse foot process effacement, a basement membrane thickness of 200-420 nm, and no electron-dense deposits. Transmission electron microscopy, ×4000.

Figure 3 Lower lip biopsy sample. Focal lymphocytic infiltration score > 1 (i.e., a 4 mm² tissue sample with at least 50 lymphocytes).