Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2021; 9(8): 1983-1988
Published online Mar 16, 2021. doi: 10.12998/wjcc.v9.i8.1983
Madelung disease: A case report
Ke-Ke Chen, Lian-Song Ni, Wei-Hui Yu
Ke-Ke Chen, Lian-Song Ni, Wei-Hui Yu, Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China
Author contributions: Chen KK collected clinical data, discussed the details, contributed to the writing; Ni LS contributed to the follow–up of the patient, and modified the manuscript; Yu WH modified the manuscript and was a major contributor in writing the manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei-Hui Yu, MD, PhD, Attending Doctor, Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, No. 2 Fuxue Alley, Wenzhou 325000, Zhejiang Province, China. shadow1201@163.com
Received: November 16, 2020
Peer-review started: November 16, 2020
First decision: December 13, 2020
Revised: January 3, 2020
Accepted: January 22, 2021
Article in press: January 22, 2021
Published online: March 16, 2021
Core Tip

Core Tip: Madelung disease (MD) is a rare disorder of fat metabolism, which results in diffuse and symmetrical deposition of adipose tissue in the subcutaneous superficial fascia space and/or deep fascia space in various parts of the body, such as the neck and shoulders, etc. Recently, a case of MD accompanied by type 2 diabetes was diagnosed and treated in our hospital. The clinical characteristics of MD are still under-recognized. Herein we discuss the pathogenesis, diagnosis and treatment of MD in order to improve the clinician’s understanding of the disease.